Microbiology News and Research

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New antibiotic beats superbugs at their own game

The problem with antibiotics is that, eventually, bacteria outsmart them and become resistant. But by targeting the gene that confers such resistance, a new drug may be able to finally outwit them.

7 Jul 2008

Scientists discover way to protect against death following plague infection

Bacteria that cause pneumonic plague can evade our first-line defences, making it difficult for the body to fight infection. In fact, a signature of the plague is the lack of an inflammatory response.

3 Jul 2008

New target for the potential treatment of tuberculosis

Scientists have uncovered a new target for the potential treatment of tuberculosis (TB), finally resolving a long-running debate about how the bacterial cell wall is built.

3 Jul 2008

New understanding of how herpes simplex virus 1 hides during inactive phase

Now that Duke University Medical Center scientists have figured out how the virus that causes cold sores hides out, they may have a way to wake it up and kill it.

3 Jul 2008

Cancer cells revert to normal at specific signal threshold

Cancer starts when key cellular signals run amok, driving uncontrolled cell growth. But scientists at the Stanford University School of Medicine report that lowering levels of one cancer signal under a specific threshold reverses this process in mice, returning tumor cells to their normal, healthy state. The finding could help target cancer chemotherapy to tumors while minimizing side effects for the body's healthy cells.

1 Jul 2008

Wound-cleaning laser kills harmful bacteria

A laser-activated antimicrobial offers hope for new treatments of bacterial infections, even those that are resistant to current drugs. Research published today in the open access journal BMC Microbiology describes the use of a dye, indocyanine green, which produces bacteria-killing chemicals when lit by a specific kind of laser light.

30 Jun 2008

Almonds may improve digestive health

Almonds, as well as being high in vitamin E and other minerals, are also thought to have other health benefits, such as reducing cholesterol. Recently published work by the Institute of Food Research has identified potential prebiotic properties of almonds that could help improve our digestive health by increasing levels of beneficial gut bacteria.

30 Jun 2008

New approach to HIV vaccine research taps Rochester expertise

A new national effort to create a vaccine against HIV will include work by a University of Rochester Medical Center rheumatologist who is an expert on a portion of the immune system that has sometimes gotten short shrift in the fight against HIV.

30 Jun 2008

Reaction to gastric bypass surgery kills mother who did it for her son

A young mother who wanted to lose weight for the sake of her son died from complications days after undergoing gastric bypass surgery.

26 Jun 2008

tRNA import occurs in humans - could lead to targeted therapies

Scientists have determined that human cells are able to shift important gene products into their own mitochondria, considered the power plants of cells. The finding could eventually lead to therapies for dozens of diseases.

24 Jun 2008

Neglected infections of poverty in the U.S. are disabling hundreds of thousands of Americans every year

An analysis published June 25th in the open-access journal PLoS Neglected Tropical Diseases highlights that diseases very similar to those plaguing Africa, Asia, and Latin America are also occurring frequently among the poorest people in the United States, especially women and children. These diseases - the "neglected infections of poverty" - are caused by chronic and debilitating parasitic, bacterial, and congenital infections.

24 Jun 2008

Radioimmunotherapy targeting viral antigens shows potential to treat or prevent viral cancers

A new study, presented at the Society of Nuclear Medicine's 55th Annual Meeting, shows that radioimmunotherapy (RIT) targeting viral antigens offers a novel option to treat-or even prevent-many viral cancers by targeting cancer cells expressing viral antigens or infected cells before they convert into malignancy.

16 Jun 2008

European researchers take lid off the genome

European researchers have made significant progress unravelling how genes are governed and why this sometimes goes wrong in disease.

15 Jun 2008

Scientist deciphers language bacterial cells use to 'talk' to each other - also discovers how to quell their conversation

Understanding the way bacterial cells "talk" to each other could lead to more effective methods for fighting the often persistent and serious infections caused by the biofilms they form, says a Texas A&M University professor of chemical engineering who not only has deciphered their language but also discovered how to quell their conversation.

11 Jun 2008

Mycobacterium tuberculosis can grow in surface-level bacteria clusters known as biofilms

University of Pittsburgh-led researchers discovered that the primary bacteria behind tuberculosis can grow on surfaces and that drug-tolerant strains flourish in these bacterial communities, the research team recently reported in Molecular Microbiology.

11 Jun 2008

New pathogen from pigs' stomach ulcers

Scientists have isolated a new bacterium in pigs' stomachs thanks to a pioneering technique, offering hope of new treatments to people who suffer with stomach ulcers, according to research published in the June issue of the International Journal of Systematic and Evolutionary Microbiology.

8 Jun 2008

New grant to enable University of Rochester to increase HIV research by 25 percent

The University of Rochester today announced that the National Institutes of Health (NIH) has awarded a team of more than 50 researchers a five-year, $3.2 million grant.

4 Jun 2008

Antibacterial wipes may spread bacteria

Antibacterial wipes which have become increasingly popular in many homes, nursing homes, schools and hospitals, may not it seems be the answer when it comes to getting rid of dangerous bacteria.

3 Jun 2008

A genetic tool for cleaner water

A genetic tool used by medical researchers may also be used in a novel approach to remove harmful microbes and viruses from drinking water.

3 Jun 2008

Despite vaccine, public should not get complacent about pneumococcal disease

Although the childhood pneumococcal conjugate vaccine has been a boon in reducing the incidence invasive pneumococcal disease (IPD), the public and the medical community must not get complacent, as non-vaccine strains, some resistant to antibiotics, are on the rise, say scientists at a meeting today in Boston.

3 Jun 2008