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Penn researchers identify major genetic factor that keeps moles in non-cancerous, no-growth state

Moles are benign tumors found on the skin of almost every adult. Scientists have known for years that a mutation in the BRAF gene makes them start growing, but until now haven't understood why they stop. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania have identified a major genetic factor that keeps moles in their usual non-cancerous, no-growth state.

6 Aug 2015

Clinical study shows two-drug combination can prolong survival in men with metastatic prostate cancer

Newly diagnosed patients with metastatic, hormone-sensitive prostate cancer gained a dramatic survival benefit when started on two drugs simultaneously, rather than delaying the second drug until the cancer began to worsen, according to results of a clinical trial led by a Dana-Farber Cancer Institute scientist.

6 Aug 2015

Genetic test may help identify better treatment option for HER2-positive breast cancer patients

A genetic test for PIK3CA mutations may help to identify patients with HER2-positive breast cancer who are less likely to benefit from combination anti-HER2 therapy, according to a study published in The Oncologist on August 5, 2015.

6 Aug 2015

AACN selects Linda L. Chlan as 2016 Distinguished Research Lecturer

The American Association of Critical-Care Nurses recently selected Linda L. Chlan, RN, PhD, FAAN, as its 2016 Distinguished Research Lecturer.

6 Aug 2015

New research shows gastric bypass surgery lowers alcohol tolerance in women

Women who have gastric bypass surgery to lose weight should keep a close eye on their alcohol consumption, according to new research at Washington University School of Medicine in St. Louis.

6 Aug 2015

Meniscal transplant surgery reduces pain, improves knee function in most patients younger than age 50

Most patients younger than age 50 with a torn or severely damaged meniscus experienced reduced pain and improved knee function following transplant surgery, according to a study in the August 5 issue of the Journal of Bone and Joint Surgery. However, many patients required additional surgery within 10 years.

6 Aug 2015

Penn research reveals additional pathway for origin of colon cancer

Cancer researchers already know of some oncogenes and other factors that promote the development of colon cancers, but they don't yet have the full picture of how these cancers originate and spread. Now researchers from the Perelman School of Medicine at the University of Pennsylvania have illuminated another powerful factor in this process.

6 Aug 2015

Johns Hopkins researchers report on more effective way to spot patients at risk of septic shock

For a patient with sepsis - which kills more Americans every year than AIDS and breast and prostate cancer combined - hours can make the difference between life and death.

6 Aug 2015

Hospital physicians rarely identify or address overweight/obesity in children

Physicians and physician trainees fail to identify or address overweight/obesity in over 90 percent of hospitalized children, according to new research from a Saint Louis University pediatric hospitalist.

6 Aug 2015

Researchers show how realistic environments affect growth of cancer tumors in bones

Researchers at Rice University and University of Texas MD Anderson Cancer Center have developed a way to mimic the conditions under which cancer tumors grow in bones.

6 Aug 2015

Diets high in sodium could be a novel risk factor in development of multiple sclerosis

Here's another reason to put the salt shaker down: New research in mice shows that diets high in sodium may be a novel risk factor in the development of multiple sclerosis (MS) by influencing immune cells that cause the disease. Although this research does implicate salt intake as a risk factor, it is important to note that dietary salt is likely just one of the many environmental factors contributing to this complex disease, and very much influenced by one's genetic background.

6 Aug 2015

Mylan announces launch of Esomeprazole Magnesium Delayed-release Capsules USP in U.S.

Mylan N.V. today announced the U.S. launch of Esomeprazole Magnesium Delayed-release Capsules USP, 20 mg and 40 mg, which is the generic version of AstraZeneca's Nexium.

6 Aug 2015

Autoantibody status fails to predict death risk in systemic sclerosis with PAH

Anticentromere and isolated nucleolar autoantibodies are prevalent in systemic sclerosis patients with pulmonary arterial hypertension, but they do not predict survival, US research shows.

5 Aug 2015

Poor relapse recovery heralds progressive MS

Multiple sclerosis patients with poor recovery from relapses develop the progressive form faster than those with good recovery, research shows.

5 Aug 2015

Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

Half of patients referred to a specialist centre with a diagnosis of chronic inflammatory demyelinating polyneuropathy do not actually have the condition, report researchers.

5 Aug 2015

Charity and uncompensated care spending vary greatly among not-for-profit hospitals

While not-for-profit hospitals receive substantial tax benefits, some do not provide free or subsidized care for a higher percentage of patients living in poverty than their for-profit counterparts, according to a study of California medical centers.

5 Aug 2015

In vitro testing provides proof of concept for osteopathic manipulative therapy

In vitro studies of the cellular effects of modeled osteopathic manipulative therapy (OMT) provide proof of concept for the manual techniques practiced by doctors of osteopathic medicine (DOs), according to researchers from the University of Arizona College of Medicine - Phoenix.

5 Aug 2015

MSK and LVHN collaborate to improve patients’ access to innovative cancer treatments

Memorial Sloan Kettering Cancer Center (MSK) and Lehigh Valley Health Network (LVHN) announced today the beginning of a unique and forward-thinking collaboration aimed at improving patient access to the latest and most effective cancer treatment advances and highest-caliber cancer care.

5 Aug 2015

Children increase parents’ risk for viral infection

The BIG LoVE (Utah Better Identification of Germs-Longitudinal Viral Epidemiology) study, led by scientists at the University of Utah School of Medicine, finds that each bundle of joy puts the entire household at increased risk for infection with viruses that cause colds, flu, and other respiratory illnesses.

5 Aug 2015

Circadian factors, host gender could help understand microbiome and its effect on inflammatory bowel disease

By now, the old saw, "You are what you eat," has been well-used in describing the microbiome. However axiomatic that phrase may be, a new study has also found that who and when that consumption is done can affect microbiome make-up.

5 Aug 2015

Medicine News and Research

Penn researchers identify major genetic factor that keeps moles in non-cancerous, no-growth state

Clinical study shows two-drug combination can prolong survival in men with metastatic prostate cancer

Genetic test may help identify better treatment option for HER2-positive breast cancer patients

AACN selects Linda L. Chlan as 2016 Distinguished Research Lecturer

New research shows gastric bypass surgery lowers alcohol tolerance in women

Meniscal transplant surgery reduces pain, improves knee function in most patients younger than age 50

Penn research reveals additional pathway for origin of colon cancer

Johns Hopkins researchers report on more effective way to spot patients at risk of septic shock

Hospital physicians rarely identify or address overweight/obesity in children

Researchers show how realistic environments affect growth of cancer tumors in bones

Diets high in sodium could be a novel risk factor in development of multiple sclerosis

Mylan announces launch of Esomeprazole Magnesium Delayed-release Capsules USP in U.S.

Autoantibody status fails to predict death risk in systemic sclerosis with PAH

Poor relapse recovery heralds progressive MS

Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

Charity and uncompensated care spending vary greatly among not-for-profit hospitals

In vitro testing provides proof of concept for osteopathic manipulative therapy

MSK and LVHN collaborate to improve patients’ access to innovative cancer treatments

Children increase parents’ risk for viral infection

Circadian factors, host gender could help understand microbiome and its effect on inflammatory bowel disease

Everything there is to know about biosimilars eBook

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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