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EORTC study: Irradiation of regional nodes in breast cancer patients has marginal effect on overall survival

At a median follow-up of 10.9 years, an EORTC study has shown that irradiation of regional nodes in patients with stage I, II, or III breast cancer has a marginal effect on overall survival, the primary endpoint (at 10 years, overall survival was 82.3 % for regional irradiation versus 80.7% for no regional irradiation, (HR=0.87 (95%CI: 0.76, 1.00), p=0.06).

4 Aug 2015

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix Corp. is pleased to announce the formation of an international Clinical Steering Committee for the RVX-208 "apabetalone" Phase 3 clinical trial BETonMACE assessing major adverse cardiac events (MACE) in high-risk vascular patients with diabetes mellitus and a recent Acute Coronary Syndrome event. BETonMACE is expected to start in the fall of 2015.

4 Aug 2015

Imperial Innovations announces launch of pre-clinical spinout company, Orthonika

Imperial Innovations is pleased to announce the launch of Orthonika, a spinout company from Imperial College London that is developing a novel knee meniscus replacement, MenisciKnit.

4 Aug 2015

California Initiative to Advance Precision Medicine selects two demonstration projects

Two demonstration projects that aim to yield quick results for patients have been selected by the new California Initiative to Advance Precision Medicine, a public-private effort launched by Governor Edmund G. Brown Jr.

4 Aug 2015

Ironshore partners with Restore Health to participate in HLD-200 clinical trial to treat ADHD

Ironshore Pharmaceuticals & Development, Inc. has signed an agreement with Restore Health, a company specializing in personalized medicine, to participate in the fulfillment of a double-blind clinical trial, designed to evaluate the safety and efficacy of HLD-200, a new drug in development to treat Attention-deficit/hyperactivity disorder (ADHD).

4 Aug 2015

Breakthroughs against Plasmodium falciparum pave way for latest advancement

When the highly-influential European Medicines Agency announced its recommendation to approve what could be the world's first licensed vaccine against malaria in infants and children, there was much celebrating in the research community at NYU Langone Medical Center.

4 Aug 2015

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

Ethiopians have lived at high altitudes for thousands of years, providing a natural experiment for studying human adaptations to low oxygen, a condition known as hypoxia. One factor that may enable Ethiopians to tolerate high altitudes and hypoxia is the endothelin receptor type B (EDNRB) gene.

4 Aug 2015

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.

4 Aug 2015

People with chronic insomnia may be able to get relief from half of standard sleeping pills

The roughly nine million Americans who rely on prescription sleeping pills to treat chronic insomnia may be able to get relief from as little as half of the drugs, and may even be helped by taking placebos in the treatment plan, according to new research published today in the journal Sleep Medicine by researchers from the Perelman School of Medicine at the University of Pennsylvania.

4 Aug 2015

Academic stress increases injury risk among college football players

Coaches and trainers strive to keep their players healthy so they can perform at their maximum potentials. Injury restrictions, or limits on athletes' physical activity due to illnesses or injuries, can keep athletes on the bench for a game or even an entire season. Now, University of Missouri researchers have found college football players are more likely to experience injuries during test weeks than during training camp.

4 Aug 2015

New ACMG Scope of Practice of the Specialty of Medical Genetics document released

The field of medical genetics is swiftly evolving. It's a period of rapid scientific discovery, new technologies and subsequent translation into medical practice, public policy and public health. But what role should the Medical Genetics specialist have since genetics impacts all patients and specialties in some way? In an effort to clearly define the changing role of the specialty of Medical Genetics and the distinction between Medical Geneticists and other genetics healthcare professionals, the American College of Medical Genetics and Genomics has has just released a new "Scope of Practice of the Specialty of Medical Genetics" document, revising its earlier 2008 Policy Statement.

4 Aug 2015

New article proposes creation of $2 billion global vaccine-development fund to prevent infectious diseases

Ebola is a preventable disease, and yet a safe and effective vaccine has not been deployed. As with many vaccines, financial barriers persist: pharmaceutical companies see high costs with limited market potential, and government support is lacking. But there may be a solution to this vaccine crisis with the ability to save at-risk populations, according to a perspective piece written by physicians based at Princeton University, University of Pennsylvania and the Wellcome Trust.

4 Aug 2015

Northwestern gets $17.5 million NIH grant to invent, develop implantable drug delivery system for HIV prevention

Northwestern Medicine scientists have received a five-year, $17.5 million grant from the National Institutes of Health for an interdisciplinary project that aims to invent, develop and test an implantable drug delivery system to protect high-risk individuals from HIV infection for up to a year at a time.

4 Aug 2015

Study examines how local factors increase odds of smoking during pregnancy

Women are more likely to smoke during pregnancy when they live in areas where socio-economic resources are lower but also where smoking is more socially accepted, according to new study from Rice University's Kinder Institute for Urban Research.

4 Aug 2015

Penn Medicine devises new approach to develop vaccines against lethal diseases

Researchers at the Perelman School of Medicine at the University of Pennsylvania have devised an entirely new approach to vaccines - creating immunity without vaccination.

4 Aug 2015

NYSCF scientists design new robotic platform to automate generation of patient-specific stem cells

Scientists at The New York Stem Cell Foundation Research Institute successfully designed a revolutionary, high-throughput, robotic platform that automates and standardizes the process of transforming patient samples into stem cells.

4 Aug 2015

NAM, FDA's CTP name 2015-2016 class of FDA Tobacco Regulatory Science Fellows

The National Academy of Medicine, formerly the Institute of Medicine, along with the Food and Drug Administration's Center for Tobacco Products (CTP) have named the 2015-2016 class of the FDA Tobacco Regulatory Science Fellows. The five individuals were chosen through a highly selective national competition based on their exceptional, diverse professional qualifications to contribute to the work of CTP.

4 Aug 2015

New Tel Aviv University study sheds light on precise trigger of deadly melanoma

Skin cancer is the most common of all cancers, and melanoma, which accounts for 2% of skin cancer cases, is responsible for nearly all skin cancer deaths. Melanoma rates in the US have been rising rapidly over the last 30 years, and although scientists have managed to identify key risk factors, melanoma's modus operandi has eluded the world of medical research.

4 Aug 2015

Pitt investigators to lead $5 million initiative to monitor resistance to HIV prevention drugs in sub-Saharan Africa

Infectious diseases researchers from the University of Pittsburgh School of Medicine are leading a five-year, $5 million initiative to monitor drug resistance during the rollout of HIV prevention drugs in sub-Saharan Africa.

4 Aug 2015

First biodegradable gene delivery system efficiently penetrates human airway mucus barrier of lung tissue

Researchers at the Johns Hopkins University School of Medicine, Johns Hopkins University Department of Chemical and Biomolecular Engineering, and Federal University of Rio de Janeiro in Brazil have designed a DNA-loaded nanoparticle that can pass through the mucus barrier covering conducting airways of lung tissue — proving the concept, they say, that therapeutic genes may one day be delivered directly to the lungs to the levels sufficient to treat cystic fibrosis (CF), chronic obstructive pulmonary disease, asthma and other life-threatening lung diseases.

4 Aug 2015

Medicine News and Research

EORTC study: Irradiation of regional nodes in breast cancer patients has marginal effect on overall survival

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Imperial Innovations announces launch of pre-clinical spinout company, Orthonika

California Initiative to Advance Precision Medicine selects two demonstration projects

Ironshore partners with Restore Health to participate in HLD-200 clinical trial to treat ADHD

Breakthroughs against Plasmodium falciparum pave way for latest advancement

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

People with chronic insomnia may be able to get relief from half of standard sleeping pills

Academic stress increases injury risk among college football players

New ACMG Scope of Practice of the Specialty of Medical Genetics document released

New article proposes creation of $2 billion global vaccine-development fund to prevent infectious diseases

Northwestern gets $17.5 million NIH grant to invent, develop implantable drug delivery system for HIV prevention

Study examines how local factors increase odds of smoking during pregnancy

Penn Medicine devises new approach to develop vaccines against lethal diseases

NYSCF scientists design new robotic platform to automate generation of patient-specific stem cells

NAM, FDA's CTP name 2015-2016 class of FDA Tobacco Regulatory Science Fellows

New Tel Aviv University study sheds light on precise trigger of deadly melanoma

Pitt investigators to lead $5 million initiative to monitor resistance to HIV prevention drugs in sub-Saharan Africa

First biodegradable gene delivery system efficiently penetrates human airway mucus barrier of lung tissue

Everything there is to know about biosimilars eBook

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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