Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

BioTime obtains license from Wistar Institute for technology related to SP100 gene

BioTime, Inc. today announced that it has obtained an exclusive license from The Wistar Institute in Philadelphia, PA for technology related to a gene designated as SP100.

25 Jan 2012

Cytori's ADRCs safe and feasible for patients with AMI

Cytori Therapeutics announced today the publication of previously reported six-month outcomes from APOLLO, the Company's European clinical trial evaluating adipose-derived stem and regenerative cells (ADRCs) in patients with acute myocardial infarction, as Research Correspondence in the Journal of the American College of Cardiology.

25 Jan 2012

Takeda receives FDA approval for VELCADE sNDA to treat MM

Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today announced that the U.S. Food and Drug Administration (FDA) has approved a supplemental new drug application (sNDA) for VELCADE(bortezomib), which updates the label to include the subcutaneous method of administration in all approved indications: multiple myeloma and mantle cell lymphoma after at least one prior therapy.

24 Jan 2012

Ikaria receives FDA orphan drug designation for use of iNO in PAH

Ikaria, Inc., a critical care company focused on developing and commercializing innovative therapies for critically ill patients, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for the use of inhaled nitric oxide (iNO) with the INOpulse DS drug-delivery system as a combination product for pulmonary arterial hypertension.

23 Jan 2012

Scientists discover finely tuned mechanism associated with CHD

Scientists at the Gladstone Institutes have identified a finely tuned mechanism by which fetal heart muscle develops into a healthy and fully formed beating heart-offering new insight into the genetic causes of congenital heart disease and opening the door to one day developing therapies to fight this chronic and potentially fatal disorder.

23 Jan 2012

Sex declared safe for heart patients

A doctors’ group on Thursday suggested that sex may be safe for most heart patients. The American Heart Association added that having sex only slightly raises the chance for a heart attack. And that’s true for people with and without heart disease. Despite the higher risk for a heart patient to have a second attack, there’s no evidence that they have more sex-related heart attacks than people without cardiac disease. The updated advice was released online Thursday in the heart association journal, Circulation.

22 Jan 2012

EMA CHMP issues positive opinion to MSD's REMICADE for treatment of pediatric UC

MSD today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion recommending the use of REMICADE (infliximab) in the treatment of severely active ulcerative colitis (UC) in pediatric patients ages 6 to 17 years, who have had an inadequate response to conventional therapy, including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies.

21 Jan 2012

New book focuses on improving care for chronic diseases

Why does health care need to be redesigned? First - the current system is broken. It costs too much, and too often yields little value for patients and society. Second - it's fixable. The editors and authors of Great Health Care - Making It Happen are convinced of it.

20 Jan 2012

$Coexisting comorbidities increase treatment costs for older adults with hip fractures$

Coexisting comorbidities increase treatment costs for older adults with hip fractures

More than 250,000 hip fractures occur every year in the U.S., often resulting in hospitalization, surgery, nursing-home admission, long-term disability, and/or extended periods of rehabilitation. Independent existing medical conditions significantly increase the treatment cost and length of hospitalization for older adults who have sustained a hip fracture, according to a new study recently published in the Journal of Bone and Joint Surgery.

19 Jan 2012

Henry Ford to conduct Apnex HGNS System clinical trial in OSA

A clinical trial is underway at Henry Ford Hospital to evaluate the safety and effectiveness of the Apnex Hypoglossal Nerve Stimulation System to treat obstructive sleep apnea.

19 Jan 2012

Minimally invasive renal denervation performed for the first time in Canada

Doctors at the Peter Munk Cardiac Centre today performed a minimally invasive surgical procedure to treat high blood pressure, called renal denervation, for the first time in Canada.

18 Jan 2012

Peter Munk Cardiac Centre doctors perform renal denervation in first Canadian patient

Doctors at the Peter Munk Cardiac Centre today performed a minimally invasive surgical procedure to treat high blood pressure, called renal denervation, for the first time in Canada. The procedure can significantly reduce high blood pressure in patients who cannot effectively treat their hypertension through drugs. These patients, numbering approximately 250,000 Canadians, have to endure an especially high risk of heart attacks and stroke, which continues to kill thousands of Canadians every year.

18 Jan 2012

State roundup: State lawmakers, governors planning health legislation; Some Pa. kids losing Medicaid

Iowa House and Senate Republicans could support legislation requiring lawmakers to contribute to the cost of their state-provided health-care benefits, party leaders told the Des Moines Register's editorial board this morning. The health-care packages now offered by the state - in which most employees, including legislators, are not required to make contributions from their salaries - are "out of touch" with the plans available to average Iowans, ... House Speaker Kraig Paulsen, R-Hiawatha, said.

18 Jan 2012

Four Loyola anesthesiologists have written chapters for Manual of Clinical Anesthesiology

Four Loyola anesthesiologists have written chapters for the Manual of Clinical Anesthesiology, a popular reference and teaching tool used in hospitals across the nation.

13 Jan 2012

Care for Asian-American heart attack patients gets better

Care for Asian-American heart attack patients improved between 2003 and 2008, according to a study published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

11 Jan 2012

Cardiologist measures risk factors associated with CR

The cardiologist Aitor Jim-nez has managed to gather and characterise in detail 110 cases of cardiac rupture (CR), after spending 22 years (1978-2000) gathering data at the Hospital de Cruces, near Bilbao. It is one of the broadest anatomical series described in this respect. CR is the most serious complication of acute myocardial infarction; it is not very common, but when it does occur, it is mortal in practically all cases. So prevention, although difficult, seems more feasible than cure.

10 Jan 2012

Cardio3BioSciences raises €3.1M in non-dilutive funding

The Belgian biotechnology company, Cardio3BioSciences, a leader in the discovery and development of regenerative and protective therapies for the treatment of cardiovascular diseases, today announces it has secured a total of €3.1 million in non-dilutive funding from the Walloon Region and the European Commission's Seventh Framework Programme.

10 Jan 2012

CMS assigns permanent J-code for Savient's KRYSTEXXA to treat RCG

Savient Pharmaceuticals, Inc. today announced that a product-specific billing code, or permanent J-code, for KRYSTEXXA (pegloticase) became available on January 1, 2012.

7 Jan 2012

Isis announces results from ISIS-TTRRx Phase 1 study on TTR amyloidosis

Isis Pharmaceuticals, Inc. announced today results from a Phase 1 study with ISIS-TTRRx. The results demonstrated that treatment with ISIS-TTRRx produced dose-dependent statistically significant reductions of greater than 80 percent in transthyretin (TTR) protein.

6 Jan 2012

CRF sponsors Seventh International Conference on Cell Therapy for Cardiovascular Disease

The Seventh International Conference on Cell Therapy for Cardiovascular Disease sponsored by the Cardiovascular Research Foundation (CRF) is a comprehensive program dedicated to the evolving field of cell-based therapies for the repair and regeneration of cardiac and vascular disease, as well as related diseases such as diabetes and stroke.

5 Jan 2012