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Combination of ramucirumab and docetaxel fails to delay advanced breast cancer progression

Adding the antibody therapy ramucirumab to the chemotherapy drug docetaxel did not delay disease progression for patients with HER2-negative, advanced breast cancer, according to results of a placebo-controlled, randomized, phase III clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

16 Dec 2013

Study: Brain blood vessel cells may be therapeutic targets for Alzheimer's disease

A study in mice shows how a breakdown of the brain's blood vessels may amplify or cause problems associated with Alzheimer's disease. The results published in Nature Communications suggest that blood vessel cells called pericytes may provide novel targets for treatments and diagnoses.

14 Dec 2013

NIH names UTHealth as one of 25 regional stroke centers

The University of Texas Health Science Center at Houston has been named one of 25 regional stroke centers by the National Institutes of Health and the only one in Texas.

14 Dec 2013

Specialists use pioneering treatment to reduce high blood pressure in kidney patient

SPECIALISTS at Sheffield Teaching Hospitals NHS Foundation Trust have used a pioneering treatment to reduce high blood pressure in a kidney patient whose blood pressure could not be controlled with conventional medication.

13 Dec 2013

JHI released epic3 guidelines on infection prevention and control for range of healthcare professionals

The Journal of Hospital Infection (JHI) has just released the awaited epic3 guidelines on infection prevention and control for a range of healthcare professionals. They are freely available online on ScienceDirect and on the journal's website.

13 Dec 2013

NIH StrokeNet to revolutionize research on stroke

A network of 25 regional stroke centers working with nearby satellite facilities will span the country, have teams of researchers representing every medical specialty needed for stroke care and will address the three prongs of stroke research: prevention, treatment and recovery. The Centers were announced today by the National Institutes of Health.

13 Dec 2013

Researchers discover new therapeutic approach for hemophilia

Researchers at the UNC School of Medicine and the Medical College of Wisconsin found that a new kind of gene therapy led to a dramatic decline in bleeding events in dogs with naturally occurring hemophilia A, a serious and costly bleeding condition that affects about 50,000 people in the United States and millions more around the world.

12 Dec 2013

PPDC receives $1.5 million grant to advance pediatric medical devices

For medical devices, as with many medicines, the market for children is a small fraction of the adult market, and there are far fewer child-sized devices. But, of course, the need exists, even if proper devices may not.

12 Dec 2013

Lund University researcher explores why type 2 diabetes raises dementia risk later in life

It is well known that type 2 diabetes raises the risk of dementia. The reasons for this are less clear, but one explanation could be insulin resistance in the brain, according to Malin Wennstr-m, a researcher at Lund University's Molecular Memory Research Unit. She has received EUR 700,000 from the Swedish Research Council to investigate her theory.

12 Dec 2013

Inflating balloon inside artery after stent placement increases patients' risk of serious complications

Johns Hopkins surgeons say skipping one commonly taken step during a routine procedure to insert a wire mesh stent into a partially blocked carotid artery appears to prevent patients from developing dangerously low blood pressure, an extremely slow heart rate or even a stroke or heart attack.

12 Dec 2013

Avinger closes significant funding round to initiate clinical trial on peripheral atherectomy catheter

Avinger, Inc. producer of therapeutic devices incorporating intravascular imaging and pioneer of the lumivascular approach to treating vascular disease, announced today the closing of a significant funding round.

12 Dec 2013

Researchers awarded $25 million NIH grant to study critical limb ischemia treatment

A team of researchers from Brigham and Women's Hospital, Boston Medical Center and Massachusetts General Hospital has been awarded $25 million by the National Institutes of Health to conduct a four-year, randomized clinical trial-the BEST-CLI Trial (Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia). The trial will compare traditional bypass surgery with the less invasive alternative of endovascular treatment for patients with critical limb ischemia.

11 Dec 2013

FDA grants indication for GORE VIABAHN Endoprosthesis to treat thrombotic occlusion

W. L. Gore & Associates today announced that the Food and Drug Administration has granted indication for the GORE VIABAHN Endoprosthesis to treat stenosis or thrombotic occlusion at the venous anastomosis of synthetic arteriovenous access grafts.

11 Dec 2013

Low sodium levels linked to poor targeted therapy outcomes in RCC

Low serum sodium levels in patients receiving targeted therapy for metastatic renal cell carcinoma (mRCC) may signal a poor outcome, study findings indicate.

11 Dec 2013

Early tumor shrinkage predicts targeted therapy efficacy in RCC

Early tumor shrinkage in patients with metastatic renal cell carcinoma following vascular endothelial growth factor-targeted therapy may herald good long-term survival, research shows.

11 Dec 2013

Daiichi Sankyo presents subgroup analysis of Hokusai-VTE study at ASH annual meeting

Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced results of a prespecified subgroup analysis of 771 cancer patients enrolled in the phase 3 Hokusai-VTE study.

11 Dec 2013

Discovery could lead to new way to combat cancer

One way to defeat an opponent is to cut off its supply lines. Tumors are no different. The supply lines for tumors are the blood vessels that ferry oxygen and nutrients to the cells. Restricting the blood vessels that feed tumor cells can shrink the tumor. A cross-institutional international team of scientists recently discovered a new, important step of the process that grows new blood vessels, a discovery that could lead to a new way to combat cancer.

11 Dec 2013

Reverse Medical gets FDA clearance to market MVP-5 Micro Vascular Plug system in the US

Reverse Medical Corporation today announced FDA clearance for US commercialization of their MVP-5 Micro Vascular Plug system for peripheral vessel embolization, and the first US clinical case. The MVP-5 system is indicated for use to obstruct or reduce the rate of blood flow in the peripheral vasculature, in vessels measuring between 3.0 and 5.0 mm.

10 Dec 2013

UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

Like tiny construction workers, cells sculpt embryonic tissues and organs in 3D space. This task is complicated and requires constant communication between cells to coordinate their actions and generate the forces that will shape their environment into complex tissue morphologies.

10 Dec 2013

Two-armed approach to vascular risk prediction

People with different blood pressures in their left and right arms have an increased risk for cardiovascular events, even if they do not have hypertension, shows a population-based analysis.

9 Dec 2013

Vascular News and Research

Combination of ramucirumab and docetaxel fails to delay advanced breast cancer progression

Study: Brain blood vessel cells may be therapeutic targets for Alzheimer's disease

NIH names UTHealth as one of 25 regional stroke centers

Specialists use pioneering treatment to reduce high blood pressure in kidney patient

JHI released epic3 guidelines on infection prevention and control for range of healthcare professionals

NIH StrokeNet to revolutionize research on stroke

Researchers discover new therapeutic approach for hemophilia

PPDC receives $1.5 million grant to advance pediatric medical devices

Lund University researcher explores why type 2 diabetes raises dementia risk later in life

Inflating balloon inside artery after stent placement increases patients' risk of serious complications

Avinger closes significant funding round to initiate clinical trial on peripheral atherectomy catheter

Researchers awarded $25 million NIH grant to study critical limb ischemia treatment

FDA grants indication for GORE VIABAHN Endoprosthesis to treat thrombotic occlusion

Low sodium levels linked to poor targeted therapy outcomes in RCC

Early tumor shrinkage predicts targeted therapy efficacy in RCC

Daiichi Sankyo presents subgroup analysis of Hokusai-VTE study at ASH annual meeting

Discovery could lead to new way to combat cancer

Reverse Medical gets FDA clearance to market MVP-5 Micro Vascular Plug system in the US

UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

Two-armed approach to vascular risk prediction

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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