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Study assesses the impact of tic suppression on brain functional connectivity in Tourette syndrome

Tourette syndrome, a neurodevelopmental disorder, causes motor and phonic "tics" or uncontrollable repeated behaviors and vocalizations. People affected by Tourette syndrome can often suppress these tics for some time before the urges become overwhelming, and researchers have long wondered at the neural underpinnings of the suppression effort.

7 Jul 2021

Baseline frailty can help better predict survival after critical care

Frailty is a better predictor than factors such as age when determining how older adults fare one year after receiving critical care.

7 Jul 2021

Aging immigrant population in the United States poses health policy challenges

A team led by Dr. Arturo Vargas Bustamante, UCLA Fielding School of Public Health professor of health policy and management and director of faculty research at the UCLA Latino Policy and Politics Initiative (LPPI), has found the United States faces a potential crisis in terms of health care for documented and undocumented immigrants.

7 Jul 2021

CDC grant aims to improve care and outcomes for stroke patients throughout Kentucky

UK HealthCare, UofL Health, the Kentucky Department for Public Health's Heart Disease and Stroke Prevention Program (KHDSP), and other state partners have been awarded the prestigious Paul Coverdell National Acute Stroke Program Grant by the Centers for Disease Control and Prevention.

7 Jul 2021

New drug can significantly reduce flashbacks and nightmares in PTSD patients

Post-traumatic stress disorder (PTSD) rings a bell for many, due to its rampant references in pop culture, and more, importantly, its prevalence in today's society. It is only probable that this disorder, which develops after shocking or dangerous events, would unfortunately affect the lives of many people.

7 Jul 2021

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Together with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called APOBEC proteins are important factors in the body's immune response and offer fast and effective protection against a large number of DNA and RNA viruses.

7 Jul 2021

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

From the bark of a puppy to the patter of rain against the window, our brains receive countless signals every second. Most of the time, we tune out inconsequential cues--the buzz of a fly, the soft rustle of leaves in the tree--and pay attention to important ones--the sound of a car horn, a bang on the door.

7 Jul 2021

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Peptide: N-glycanase (NGLY1) is an evolutionarily conserved enzyme for removing N-linked glycans (N-glycans) from glycoproteins and is involved in proteostasis of N-glycoproteins in the cytosol. In 2012, a rare genetic disorder called NGLY1 deficiency was discovered by an exome analysis.

7 Jul 2021

Mindfulness-based therapy could be a viable treatment for insomnia

Sleep problems are common in the general population with up to half of Singaporean adults reporting insufficient or unsatisfying sleep. Sleep quality tends to worsen with age and poor sleep is a modifiable risk factor for multiple disorders, including cardiovascular disease and cognitive impairment.

7 Jul 2021

Uncovering cellular mechanism related to gene silencing therapies

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

A recent study by scientists from Japanese universities has shown that the shape of cell-derived nanoparticles, known as "extracellular vesicles" (EVs), in body fluids could be a biomarker for identifying types of cancer.

7 Jul 2021

Adults with ADHD at higher risk of many physical conditions, finds study

Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry.

7 Jul 2021

Study unravels the link between chromosomal instability and cellular senescence

Chromosomal instability is a feature of solid tumours such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence.

7 Jul 2021

Study explores the intersection of culture and health among Mexican women and children

As we move through life, our bodies get older. Aging is inevitable, but how fast it happens can vary considerably. Physical and environmental stressors can accelerate the process, and culture may interact with biology in ways that are not fully explored.

7 Jul 2021

Skin pigmentation mechanism confers major protection against UV-related cancers

A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).

7 Jul 2021

Vaccinate big cats? New report shows SARS-CoV-2 Delta variant infecting endangered lions

There is evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infecting animals such as ferrets, fruit bats, and cats. New research led by Vijendra Pal Singh from the ICAR-National Institute of High Security Animal Disease in India suggests it might be time to vaccinate the big cats as well. Their report details SARS-CoV-2 infection in nine Asiatic lions caused by the SARS-CoV-2 Delta variant (B.1.617.2).

7 Jul 2021

University of Liverpool signs option agreement with BARD1 for type 3C diabetes test

The University of Liverpool has signed a two year option agreement with the Australian diagnostics company, BARD1 Life Sciences Ltd (ASX: BD1), for a type 3c diabetes (T3cDM) blood test. The test uses patented technology developed by researchers in the University of Liverpool's Institute of Systems, Molecular and Integrative Biology.

7 Jul 2021

SARS-CoV-2 Lambda variant spreading rapidly in South America, report reveals

A new research paper by researchers in Peru describes a new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) known as the Lambda variant (C.37). The Lambda variant was first reported in Lima, Peru, in December 2020, and from April 2021, nearly all the coronavirus infections in the country are caused by it.

7 Jul 2021

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.

7 Jul 2021

Inventor gender gap partially responsible for many missing female-focused inventions

Necessity is the father of invention, but where is its mother? According to a new study published in Science, fewer women hold biomedical patents, leading to a reduced number of patented technologies designed to address problems affecting women.

7 Jul 2021

Research News and Research

Study assesses the impact of tic suppression on brain functional connectivity in Tourette syndrome

Baseline frailty can help better predict survival after critical care

Aging immigrant population in the United States poses health policy challenges

CDC grant aims to improve care and outcomes for stroke patients throughout Kentucky

New drug can significantly reduce flashbacks and nightmares in PTSD patients

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Mindfulness-based therapy could be a viable treatment for insomnia

Uncovering cellular mechanism related to gene silencing therapies

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

Adults with ADHD at higher risk of many physical conditions, finds study

Study unravels the link between chromosomal instability and cellular senescence

Study explores the intersection of culture and health among Mexican women and children

Skin pigmentation mechanism confers major protection against UV-related cancers

Vaccinate big cats? New report shows SARS-CoV-2 Delta variant infecting endangered lions

University of Liverpool signs option agreement with BARD1 for type 3C diabetes test

SARS-CoV-2 Lambda variant spreading rapidly in South America, report reveals

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Inventor gender gap partially responsible for many missing female-focused inventions

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