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Exhausted army of immune cells may damage the very body they are supposed to protect

An 'exhausted' army of immune cells may not be able to fight off infection, but if its soldiers fight too hard they risk damaging the very body they are meant to be protecting, suggests new research from the University of Cambridge.

30 Jun 2015

Scientists develop high-throughput strategy to build de novo genomes

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new approach to build nearly complete genomes by combining high-throughput DNA sequencing with genome mapping. The methodology enabled researchers to detect complex forms of genomic variation, critically important for their association with human disease, but previously difficult to detect.

30 Jun 2015

Study could point the way to new treatments for people with severe asthma

The immune response that occurs in patients with severe asthma is markedly different than what occurs in milder forms of the lung condition, according to researchers from the University of Pittsburgh School of Medicine. Those unique features could point the way to new treatments, they said in an article published online today in the Journal of Clinical Investigation.

30 Jun 2015

Two years may be a more practical survival goal for patients with follicular lymphoma

The goal for many cancer patients is to reach the five-year, disease-free mark, but new research from UR Medicine's Wilmot Cancer Institute suggests that two years might be a more practical survival goal for people with follicular lymphoma.

30 Jun 2015

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

Canada's first human gene therapy trial for eyes -- the replacement of a faulty gene with a healthy one -- is now underway at the Royal Alexandra Hospital to preserve and potentially restore vision for people with a genetic disorder that leaves them blind by middle age.

30 Jun 2015

Study on fruit flies, brewer's yeast may provide clues about cause of Spinal Muscular Atrophy

Scientists at the University of Malta and the Institut de Génétique Moléculaire de Montpellier (CNRS/Université de Montpellier) have shown that fruit flies and brewer's yeast can reveal clues about the cause of Spinal Muscular Atrophy (SMA), the most common genetic killer of infants.

30 Jun 2015

Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

The amphetamine-based drug Evekeo, given once or twice daily to children 6-12 years of age, is effective in treating attention-deficit/hyperactivity disorder (ADHD) symptoms and improving performance in a laboratory classroom setting, according to the results of a new study published in the Journal of Child and Adolescent Psychopharmacology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Jun 2015

Athletes need to drink when thirsty to avoid exercise-associated hyponatremia

For hikers, football players, endurance athletes, and a growing range of elite and recreational exercisers, the best approach to preventing potentially serious reductions in blood sodium level is to drink when thirsty, according to an updated consensus statement on exercise-associated hyponatremia (EAH).

30 Jun 2015

Residents’ participation does not increase patients’ risks of postoperative complications after brain and spine surgeries

An analysis of the results of more than 16,000 brain and spine surgeries suggests patients have nothing to fear from having residents — physicians-in-training — assist in those operations.

30 Jun 2015

Neighborhood physical and social environments may affect type 2 diabetes risk

Neighborhood resources to support greater physical activity and, to a lesser extent, healthy diets appear to be associated with a lower incidence of type 2 diabetes, although the results vary by the method of measurement used, according to an article published online by JAMA Internal Medicine.

30 Jun 2015

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1.

30 Jun 2015

Scientists examine rates of secondary mutations in biomarker genes

Many tests for predictive biomarkers in tumors focus on selected known mutations or regions (e.g. hotspot panels). In a new study, scientists at Molecular Health examined the rates of secondary mutations in known biomarker genes and their potential impact on the diagnostic reliability of specific single-nucleotide variant (SNV) biomarker testing.

29 Jun 2015

Elsevier announces highlights of 2014 Impact Factor performance

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the highlights of its journal Impact Factor performance in 2014. According to the 2014 Journal Citation Reports (JCR) published by Thomson Reuters, Elsevier saw 55% of its journal Impact Factors increase from 2013 to 2014, ahead of the aggregate across other journals.

29 Jun 2015

Researchers develop world's first prognosis scoring system for life expectancy of patients in hospitals

Researchers at the MedUni Vienna's University Department of Anaesthetics, General Intensive Care Medicine and Pain Therapy, the University Department of Internal Medicine III and the Centre for Medical Statistics, Information Technology and Intelligent Systems have developed the world's first prognosis scoring system (PANDORA score) for hospital patients and their life expectancy within the next 30 days.

29 Jun 2015

Artemisinin and the fight against malaria: an interview with Dr. Robert Sebbag, Sanofi

Since 2014, more than 16 million anti-malarial treatments derived from the Sanofi patented process for semi-synthetic artemisinin have been supplied to endemic countries in Africa.

From Sanofi 28 Jun 2015

Study proposes use of soft computing solutions to predict survival in multiple trauma patients

The NUP/UPNA-Public University of Navarre has developed a piece of work that applies soft computing solutions to predicting survival in multiple trauma patients.

27 Jun 2015

SNSF’s special programme aims to support clinical studies initiated by researchers

Physicians and drug developers do not always have the same research questions. The new special programme Investigator Initiated Clinical Trials (IICT) will enable independent clinical researchers to answer questions that are important for patients.

27 Jun 2015

Two physician-scientists in search for better Alzheimer's disease treatment

Two of the nation's leading physician-scientists in the search to better understand and treat Alzheimer's disease - William Mobley, MD, PhD, and Michael Rafii, MD, PhD - have been named interim co-directors of the Alzheimer's Disease Cooperative Study (ADCS), a major initiative formed in 1991 as a cooperative agreement between the National Institute on Aging (NIA) and the University of California, San Diego.

27 Jun 2015

Study: Disconnect between patients and physicians on use of online communication tools

A large number of patients use online communication tools such as email and Facebook to engage with their physicians, despite recommendations from some hospitals and professional organizations that clinicians limit email contact with patients and avoid "friending" patients on social media, new research suggests.

27 Jun 2015

Implementation of public health strategies can improve survival rates of cardiac arrest in US

The Institute of Medicine Committee on the Treatment of Cardiac Arrest is announcing results of a new report that examines current statistics and survival rates of cardiac arrest in the United States, assesses evidence on existing lifesaving therapies, and recommends public health strategies that – if implemented – will improve cardiac arrest survival rates. Additionally, the report explores cardiopulmonary resuscitation (CPR) and the use of

27 Jun 2015

Medicine News and Research

Exhausted army of immune cells may damage the very body they are supposed to protect

Scientists develop high-throughput strategy to build de novo genomes

Study could point the way to new treatments for people with severe asthma

Two years may be a more practical survival goal for patients with follicular lymphoma

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

Study on fruit flies, brewer's yeast may provide clues about cause of Spinal Muscular Atrophy

Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

Athletes need to drink when thirsty to avoid exercise-associated hyponatremia

Residents’ participation does not increase patients’ risks of postoperative complications after brain and spine surgeries

Neighborhood physical and social environments may affect type 2 diabetes risk

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Scientists examine rates of secondary mutations in biomarker genes

Elsevier announces highlights of 2014 Impact Factor performance

Researchers develop world's first prognosis scoring system for life expectancy of patients in hospitals

Artemisinin and the fight against malaria: an interview with Dr. Robert Sebbag, Sanofi

Study proposes use of soft computing solutions to predict survival in multiple trauma patients

SNSF’s special programme aims to support clinical studies initiated by researchers

Two physician-scientists in search for better Alzheimer's disease treatment

Study: Disconnect between patients and physicians on use of online communication tools

Implementation of public health strategies can improve survival rates of cardiac arrest in US

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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