Blood Vessels News and Research

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Research highlighting treatment for pediatric SCD, malaria presented at ASH 2010

Red blood cells have the very important role of carrying oxygen from the lungs to the rest of the body; therefore, disorders that affect RBCs can have a significant impact on quality of life. Sickle cell disease and malaria are two common RBC diseases that affect a significant portion of the U.S. and global populations. Sickle cell disease, a genetic blood disorder that causes deformed and dysfunctional red blood cells, affects an estimated 70,000 to 100,000 Americans, while malaria affects approximately 1,500 Americans annually and 190 to 311 million people worldwide.

6 Dec 2010

Conference focuses on new molecular, mechanical solutions to improve surgeries

A two-day conference at the University of Chicago Medical Center is designed to offer surgeons a peek at the profession's future by focusing on new molecular and mechanical solutions to three age-old problems: preventing the breakdown of anastomoses (the surgically created connections between blood vessels), improving tissue healing after surgery and developing new tools to test and sharpen surgical skills.

4 Dec 2010

New clues into mechanisms underlying antiphospholipid syndrome

Thanks to findings by UT Southwestern Medical Center researchers, individuals with a potentially life-threatening condition predisposing them to blood clots, or thrombosis, might someday receive therapy to prevent the condition.

4 Dec 2010

Dysfunction in blood vessels plays a role in Alzheimer's disease development

A dysfunction in the lining of blood vessels that is linked to cardiovascular illness also appears to play a role in the development of Alzheimer's disease, according to a study published in Circulation Research: Journal of the American Heart Association.

3 Dec 2010

New analysis of stenting vs. endarterectomy for carotid occlusive disease

Doctors have long known that patients with carotid artery stenosis, narrowed blood vessels in the neck, are at significant risk for a stroke. The condition has severe implications. Annually, in the United States, 795,000 patients have strokes that often result in long-term disability or death. For years, however, researchers in North America and Europe have tried to determine the most effective method to treat narrowed or partially blocked carotid vessels.

2 Dec 2010

Noncancerous cells from primary site appear to facilitate tumor growth: Study

The process of metastasis requires that cancer cells traveling from a primary tumor find a hospitable environment in which to implant themselves and grow. A new study from Massachusetts General Hospital (MGH) Cancer Center researchers finds that circulating tumor cells prepare this environment by bringing along from their original site noncancerous cells that support tumor growth. The report has been published online in PNAS Early Edition.

1 Dec 2010

Cordis to distribute OSTIAL PRO Stent Positioning System worldwide

Cordis Corporation has entered into a distribution agreement with Ostial Solutions for the worldwide distribution of the OSTIAL PRO Stent Positioning System™. The OSTIAL PRO™ is the world's first and only aorto-ostial stent positioning system for coronary and peripheral applications. The OSTIAL PRO™ is intended to optimize the treatment of patients who require a stent implantation for treatment for aorto-ostial blockages.

30 Nov 2010

New ultrasound-based treatment for varicose veins

Rowena Cheng, RN, has spent most of her 34-year career on her feet. Standing for long periods of time comes with the job of being a nurse. For Cheng, however, it exacted a physical toll: knotted, swollen blood vessels in the calf of her left leg.

30 Nov 2010

Photoacoustic tomography and gold nanobeacons help researchers view blood vessel formation

See it for yourself: a new breakthrough in imaging technology using a combination of light and sound will allow health care providers to see microscopic details inside the body. Access to this level of detail potentially eliminates the need for some invasive biopsies, but it also has the potential to help health care providers make diagnoses earlier than ever before-even before symptoms arise. Details describing this advance are published online in the FASEB Journal (http://www.fasebj.org/content/early/2010/11/19/fj.10-171728.abstract).

23 Nov 2010

Researchers investigate ways to counteract unhealthy effects of fat

A fat yet muscular mouse is helping researchers learn whether more muscle improves the cardiovascular health of obese individuals. We are looking for ways to counteract the unhealthy effects of fat, said Dr. David Stepp, vascular biologist at the Medical College of Georgia Vascular Biology Center and co-director of MCG's Diabetes & Obesity Discovery Institute.

23 Nov 2010

Acthar Gel may be a viable treatment option for resistant nephrotic syndrome

On November 20 at the American Society of Nephrology 43rd Annual Meeting, Columbia University Assistant Professor of Clinical Medicine Andrew Bomback, MD, presented results from a patient case series assessing the potential therapeutic value of H.P. Acthar Gel (repository corticotropin injection) as a treatment for patients with nephrotic syndrome, a kidney disorder characterized by excessive loss of urinary protein.

22 Nov 2010

Alexion's Soliris Phase 2 clinical study for aHUS meets primary, secondary endpoints

Alexion Pharmaceuticals, Inc. announced today that a Phase 2 clinical study investigating Soliris (eculizumab) as a treatment for patients with atypical Hemolytic Uremic Syndrome (aHUS) who are resistant to plasma therapy met primary and key secondary endpoints with high levels of statistical and clinical significance, according to results presented today at the American Society of Nephrology (ASN) annual meeting in Denver.

21 Nov 2010

CSU invents artificial body parts that look, feel, behave, and bleed like real skin, muscles and vessels

In the last 50 years, modern medicine has made astounding advances in surgery, yet many of today's veterinary and human medicine students still hone basic surgical and suturing skills on carpet pads and pig's feet before transitioning to a live patient. An invention by Colorado State University veterinarians provides students with artificial body parts that look, feel, behave, and even bleed just like real skin, muscles and vessels.

20 Nov 2010

K.U.Leuven researchers receive ERC Advanced Grants

K.U.Leuven researchers Peter Carmeliet and Bart De Strooper have both been awarded Advanced Grants from the European Research Council. ERC Advanced Grants are the most prestigious European research grants, spanning a period of 5 years. Peter Carmeliet of the VIB Vesalius Research Centre, K.U.Leuven, will receive approximately 2.5 million euro for research focused on stopping the energy supply into blood vessels.

20 Nov 2010

Scientists discover Notch pathway may play a role in alcohol's protective effects

Many studies support the assertion that moderate drinking is beneficial when it comes to cardiovascular health, and for the first time scientists have discovered that a well-known molecule, called Notch, may be behind alcohol's protective effects. Down the road, this finding could help scientists create a new treatment for heart disease that mimics the beneficial influence of modest alcohol consumption.

20 Nov 2010

High CRP and low protein albumin levels associated with increased risk of death after PEG-operations

The combination of high CRP and low levels of the protein albumin in the blood, is associated with an increased risk of death after a PEG-operation; implantation of a nutritional catheter into the stomach through the abdominal wall. This was shown in a new study from the Swedish medical university Karolinska Institutet, published in the scientific journal Gastrointestinal Endoscopy. Of the PEG patients in the study that showed both current indicators, 20 percent died within 30 days.

20 Nov 2010

Fifth gene defect, 47 DNA regions linked to thoracic aortic disease: Researchers

Discovery of a fifth gene defect and the identification of 47 DNA regions linked to thoracic aortic disease are the subject of studies released this month involving researchers at The University of Texas Health Science Center at Houston.

19 Nov 2010

ImmunoGen presents positive data on IMGN388 anticancer compound at EORTC-NCI-AACR Symposium

ImmunoGen, Inc., a biotechnology company that develops antibody-based anticancer products using its Targeted Antibody Payload (TAP) technology, today announced the presentation of encouraging clinical data for the Company's IMGN388 anticancer compound at the 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics taking place in Berlin, Germany.

19 Nov 2010

Research suggests new therapeutic approach to prevent transplant rejection

UCLA researchers have pinpointed the culprit behind chronic rejection of heart, lung and kidney transplants. Published in the Nov. 23 edition of Science Signaling, their findings suggest new therapeutic approaches for preventing transplant rejection and sabotaging cancer growth.

19 Nov 2010

ACE-041 drug may provide new option to treat cancer

Researchers have found that a newly developed drug, which is aimed at a particular receptor involved in the development of blood vessels that sustain tumour growth, is active in patients with advanced cancers and, in some cases, has halted the progress of the disease. The drug, ACE-041, targets a different molecular pathway to other anti-angiogenesis drugs and may provide a new option to treat cancer.

19 Nov 2010

Blood Vessels News and Research

Research highlighting treatment for pediatric SCD, malaria presented at ASH 2010

Conference focuses on new molecular, mechanical solutions to improve surgeries

New clues into mechanisms underlying antiphospholipid syndrome

Dysfunction in blood vessels plays a role in Alzheimer's disease development

New analysis of stenting vs. endarterectomy for carotid occlusive disease

Noncancerous cells from primary site appear to facilitate tumor growth: Study

Cordis to distribute OSTIAL PRO Stent Positioning System worldwide

New ultrasound-based treatment for varicose veins

Photoacoustic tomography and gold nanobeacons help researchers view blood vessel formation

Researchers investigate ways to counteract unhealthy effects of fat

Acthar Gel may be a viable treatment option for resistant nephrotic syndrome

Alexion's Soliris Phase 2 clinical study for aHUS meets primary, secondary endpoints

CSU invents artificial body parts that look, feel, behave, and bleed like real skin, muscles and vessels

K.U.Leuven researchers receive ERC Advanced Grants

Scientists discover Notch pathway may play a role in alcohol's protective effects

High CRP and low protein albumin levels associated with increased risk of death after PEG-operations

Fifth gene defect, 47 DNA regions linked to thoracic aortic disease: Researchers

ImmunoGen presents positive data on IMGN388 anticancer compound at EORTC-NCI-AACR Symposium

Research suggests new therapeutic approach to prevent transplant rejection

ACE-041 drug may provide new option to treat cancer

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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