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Viewpoint: Could infectious pathogens play a role in Alzheimer's disease?

For researchers investigating Alzheimer's Disease (AD), a devastating neurodegenerative illness afflicting close to 6 million Americans, it is the best and worst of times.

18 Mar 2020

Using 'organs-on-a-chip' to study chronic inflammatory diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

18 Mar 2020

Bacterial extracellular vesicles could combat antibiotic resistance

Children's National Hospital researchers for the first time have isolated bacterial extracellular vesicles from the blood of healthy donors, a critical step to better understanding the way gut bacteria communicate with the rest of the body via the bloodstream.

18 Mar 2020

Immune mechanism in the brain appears to play key role in the development of Alzheimer's

An immune reaction in the brain seems to play a major role in the development of Alzheimer's disease. In a way, it "adds fuel to the fire" and apparently causes an inflammation that, in a sense, keeps kindling itself. The study has now been published in the journal Cell Reports.

18 Mar 2020

MCL1 protein essential in protecting the intestine against cancer development

An international team of researchers from the University of Zurich, the University Hospital Zurich, Heidelberg and Glasgow has identified a novel function for the cell death regulating protein MCL1: It is essential in protecting the intestine against cancer development – independent of bacterial-driven inflammation.

18 Mar 2020

Engineered botox more effective

A new study reports on an engineered botulinum neurotoxin (botox) that is more effective as well as safer to use in various medical procedures. The study was published in March 2020 in the open-access journal PLOS Biology.

17 Mar 2020

Changes in cellular degradation hubs can lead to cancer

A team of scientists at Uppsala University has revealed that alterations in cells’ lysosomes underly abnormal cell growth.

17 Mar 2020

Scientists use artificial intelligence to create new proteins unseen in nature

Researchers have presented a artificial intelligence method for developing new proteins that have never been seen in nature.

17 Mar 2020

Scientists engineer silkworms to produce different variants of adhesion molecules

Silkworms are useful for more than just making strong and absorbent strings of silky thread for the textiles industry.

16 Mar 2020

Key antibiotic used for treating drug-resistant TB does not work as expected

Crick and Imperial researchers have found that a key antibiotic widely used to treat drug-resistant tuberculosis does not work as expected - a finding which could be used to develop new drugs.

16 Mar 2020

Breast milk may help protect preemies from developing sepsis

A component of breast milk may help protect premature babies from developing sepsis, a fast-moving, life-threatening condition triggered by infection.

16 Mar 2020

Clinicians urged to reconsider controversial acne treatment

Acne treatment including the highly effective acne medication isotretinoin should be made more readily available despite reports of its association with depression and teen suicide.

16 Mar 2020

New, rubber-like material could act as replacement for human tissue

Researchers from Chalmers University of Technology, Sweden, have created a new, rubber-like material with a unique set of properties, which could act as a replacement for human tissue in medical procedures.

16 Mar 2020

Bacteria multiply and grow into biofilms like settlers form cities

Microbiologists have long adopted the language of human settlement to describe how bacteria live and grow: They "invade" and "colonize." Relations dwelling in close proximity are "colonies."

13 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

New method will enable production of tailor-made vaccines

Vaccines can be far more targeted and effective than they are today. A new method will allow us to develop new vaccines more cheaply and efficiently and perhaps get one step ahead of bacteria.

13 Mar 2020

Fecal Microbiota Transplants highly successful in treating patients with C.diff infection

A new study from the University of Birmingham has shown that Fecal Microbiota Transplants (FMT) are highly successful in treating patients with Clostridioides difficile (C.diff) infection.

13 Mar 2020

Gut microbiota generate bursts of diversity at unprecedented amounts

Scientists lead by Isabel Gordo, catch in real time the emergence of bursts of diversity in the microbiota, caused by bacterial cells with mutation rates similar to those of cancer.

12 Mar 2020

New nano strategy for 'trapping and zapping' antibiotic resistant genes

It's not enough to take antibiotic-resistant bacteria out of wastewater to eliminate the risks they pose to society. The bits they leave behind have to be destroyed as well.

12 Mar 2020

Air pollution exposure takes a heavy toll on gut bacteria, boosting risk of chronic illnesses

Breathing dirty air takes a heavy toll on gut bacteria, boosting risk of obesity, diabetes, gastrointestinal disorders and other chronic illnesses, new University of Colorado Boulder research suggests.

11 Mar 2020