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Researchers start Phase I clinical trial of implantable vaccine for treatment of melanoma

A cross-disciplinary team of scientists, engineers, and clinicians announced today that they have begun a Phase I clinical trial of an implantable vaccine to treat melanoma, the most lethal form of skin cancer.

7 Sep 2013

Thrombogenics, Bicycle Collaborate On Drugs Targeting Eye Diseases

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5 Sep 2013

Hokusai-VTE findings provide fresh insight into patients with pulmonary embolism

In the treatment of venous thromboembolism (VTE), the oral anticoagulant edoxaban resulted in equal efficacy and better safety compared to standard warfarin when either drug was used with initial low molecular weight heparin (LMWH), according to the results of the Hokusai-VTE trial.

5 Sep 2013

ThromboGenics, Bicycle to develop and commercialize novel drugs for ophthalmic diseases

ThromboGenics NV, a biopharmaceutical company focused on developing and commercializing innovative ophthalmic medicines, today announces that it has entered into a collaboration and license agreement with Bicycle Therapeutics to develop and commercialize novel drugs inhibiting a specific target for the treatment of ophthalmic diseases, such as diabetic macular edema.

5 Sep 2013

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Case Western Reserve researchers have identified a genetic factor that blocks the blood vessel inflammation that can lead to heart attacks, strokes and other potentially life-threatening events.

5 Sep 2013

Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia

Resveratrol, a polyphenolic compound, is synthesized in several plants and possesses beneficial biological effects, which include anti-oxidant, anti-inflammatory and anti-carcinogenic properties.

5 Sep 2013

Increased risk caused by smoking is completely reversed after smoking cessation

Dr Dohi said: "Smokers are twice as likely to have a heart attack as people who have never smoked. Quitting smoking is the most important thing people can do to reduce their risk of cardiovascular disease. But until now, studies have not examined whether the increased risk caused by smoking is completely reversed after smoking cessation."

4 Sep 2013

Obese people with high insulin levels likely to experience better blood vessel function following weight loss

Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have found that among obese people who had lost considerable weight, those with high insulin levels--a marker of insulin resistance in the body--were the most likely to experience better blood vessel function following the weight loss. These findings appear online in the Journal of the American College of Cardiology.

4 Sep 2013

Women are 25% less likely to die post TAVI than men, says doctor

Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

2 Sep 2013

Combination of music and exercise training improves endothelial function in CAD patients

Professor Deljanin Ilic said: "In the setting of cardiovascular risk factors and cardiovascular disease the endothelium loses its normal function.1 Since endothelium derived nitric oxide is necessary to maintain an adequate vascular response, correction of endothelial dysfunction has become a goal of therapy."

2 Sep 2013

Study finds that high potency statins can beat dementia

Dr Lin said: "Statins are widely used in the older population to reduce the risk of cardiovascular disease. But recent reports of statin-associated cognitive impairment have led the US Food and Drug Administration (FDA) to list statin-induced cognitive changes, especially for the older population, in its safety communications."

2 Sep 2013

Findings could alter ways in which doctors use platelets to treat traumatic injuries

A new finding could lead to novel treatments to reduce bleeding in trauma and severe infections.

2 Sep 2013

Urinary protein may be early warning sign regarding patients' cognitive abilities

The presence of protein in the urine may be a marker of risk for future cognitive decline in patients with type 2 diabetes and normal kidney function, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

30 Aug 2013

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

Tumor vessel density linked to mRCC treatment response

Changes in tumor vessel density correlate with response and resistance to anti-angiogenic therapy in patients with metastatic renal cell carcinoma, study findings suggest.

28 Aug 2013

Muscle density improves mRCC prognosis prediction

Patients with metastatic renal cell carcinoma treated with targeted therapies have a better prognosis if they also have a high quality of muscle, study findings indicate.

28 Aug 2013

UTHealth researchers find cause for rare type of bleeding disorder

Fifteen years ago, a hematologist came to Dianna Milewicz, M.D., Ph.D., with a puzzle: Multiple generations of an East Texas family suffered from a moderately severe bleeding disorder, but it wasn't hemophilia.

28 Aug 2013

Researchers develop therapeutic algorithm to study outcomes in epistaxis management

Approximately 60 percent of people experience epistaxis, commonly known as nosebleed, at least once in their lifetime. Of those who experience nosebleed, six percent require medical treatment. A study in the September 2013 issue of Otolaryngology-Head and Neck Surgery, explores which nosebleed treatment options demonstrate the best outcomes.

27 Aug 2013

Ability to draw spontaneously may be preserved in brains of artists even after vascular dementia

The ability to draw spontaneously as well as from memory may be preserved in the brains of artists long after the deleterious effects of vascular dementia have diminished their capacity to complete simple, everyday tasks, according to a new study by physicians at St. Michael's Hospital.

26 Aug 2013

Innovative memory aid system for dementia patients

A NEW ‘home help’ website giving dementia patients timely reminders and reassuring them of key visits of family, relatives, social activities and carers is being trialled in a care home in Sheffield.

23 Aug 2013

Vascular News and Research

Researchers start Phase I clinical trial of implantable vaccine for treatment of melanoma

Thrombogenics, Bicycle Collaborate On Drugs Targeting Eye Diseases

Hokusai-VTE findings provide fresh insight into patients with pulmonary embolism

ThromboGenics, Bicycle to develop and commercialize novel drugs for ophthalmic diseases

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia

Increased risk caused by smoking is completely reversed after smoking cessation

Obese people with high insulin levels likely to experience better blood vessel function following weight loss

Women are 25% less likely to die post TAVI than men, says doctor

Combination of music and exercise training improves endothelial function in CAD patients

Study finds that high potency statins can beat dementia

Findings could alter ways in which doctors use platelets to treat traumatic injuries

Urinary protein may be early warning sign regarding patients' cognitive abilities

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

Tumor vessel density linked to mRCC treatment response

Muscle density improves mRCC prognosis prediction

UTHealth researchers find cause for rare type of bleeding disorder

Researchers develop therapeutic algorithm to study outcomes in epistaxis management

Ability to draw spontaneously may be preserved in brains of artists even after vascular dementia

Innovative memory aid system for dementia patients

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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