Immune Response News and Research

RSS

New technique may yield insights on the immune response to intestinal parasite infections

A new technique may help scientists study the body's immune response to intestinal parasite infections one gut cell at a time, according to a study published today in eLife.

11 Feb 2020

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.

11 Feb 2020

Developing enhanced personalized cancer vaccines

Therapeutic cancer vaccines were first developed 100 years ago and have remained broadly ineffective to date. Before tangible results can be achieved, two major obstacles must be overcome.

11 Feb 2020

Free radicals from immune cells linked to salt-sensitive hypertension

In salt-sensitive hypertension, immune cells gather in the kidneys and shoot out free radicals, heightening blood pressure and damaging this pair of vital organs, scientists report.

11 Feb 2020

Finding a cure for canine gliomas may help find treatment for human brain cancer

Cancer research using experimental models--everything from cancer cells in a dish to patient tumors transplanted in mice--has been extremely useful for learning more about the disease and how we might treat it.

10 Feb 2020

Bats' fierce immune response to viruses could drive zoonotic emergence

It's no coincidence that some of the worst viral disease outbreaks in recent years -- SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus -- originated in bats.

10 Feb 2020

Researchers simulate leaky gut conditions using 3D models of human intestines

Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut" -- in which microbes and other molecules seep out of the intestines -- may be more common, and more harmful, than previously thought.

10 Feb 2020

Powerful vaccine could boost the effectiveness of cancer immunotherapy

Supercharging the mutation rate in cancer cells can create a powerful vaccine that is able to boost the effectiveness of immunotherapy, a major new study reports.

9 Feb 2020

New strategy uses iPSCs to regulate immune reaction to transplanted tissues

Scientists suggest a new strategy that uses induced pluripotent stem cells (iPSCs) to regulate immune reaction to transplanted tissues.

9 Feb 2020

Coronavirus - pandemic or not?

The coronavirus strain called 2019-nCoV has been causing widespread illness in China, with 28,276 affected by the virus and over 565 deaths worldwide, mostly in China. As of now, it is already more deadly than the SARS epidemic that raged between 2002 and 2004.

6 Feb 2020

Study may suggest new therapeutic approaches to control immune responses

Researchers have provided new insight on the role of cyclic AMP (cAMP) in regulating the immune response.

5 Feb 2020

Making it all work: brain-dependent immune activation in embryos

How does the immune system develop its functionality? This has been an ongoing area of research for biologists. Now, a new study published in the journal NPJ Regenerative Medicine in February 2020 shows that in very early fetal life the brain must signal directions to the developing immune system to help it defend the body from infectious agents. This signaling markedly improves the capability of the embryo to survive when faced with bacterial infection.

4 Feb 2020

Promising HIV vaccine fails in a large-scale clinical trial

The human immune deficiency virus (HIV) is an infectious disease that can lead to immunosuppression called acquired immunodeficiency syndrome (AIDS). For decades, scientists race to discover a vaccine that can help prevent the spread of the virus. The latest trial testing a new experimental vaccine in South Africa end in disappointment after deeming ineffective in preventing infection.

4 Feb 2020

FDA-approved OIT product marks major milestone in management of peanut allergies

In February 2020, the U.S. Food and Drug Administration (FDA) approved Palforzia, the first peanut powder product designed to help reduce the risk of severe peanut-induced allergic reactions through desensitization over time.

4 Feb 2020

Flickering light triggers the brain to release signaling chemicals that may help fight Alzheimer's

For over a century, Alzheimer's disease has confounded all attempts to treat it. But in recent years, perplexing experiments using flickering light have shown promise.

4 Feb 2020

Researchers develop novel therapeutic approach to cure chronic hepatitis B

Researchers at Helmholtz Zentrum München, Technical University of Munich (TUM) and the German Center for Infection Research have developed a novel therapeutic approach to cure chronic hepatitis B.

3 Feb 2020

Investigational HIV vaccine not effective in preventing HIV

The National Institute of Allergy and Infectious Diseases), part of the National Institutes of Health, has stopped administration of vaccinations in its HVTN 702 clinical trial of an investigational HIV vaccine.

3 Feb 2020

HIV antibody therapy improves immune function

A new study published in the journal Nature Medicine in February 2020 reports that the administration of neutralizing antibodies against HIV improve the recipient’s specific T cell responses against the virus.

3 Feb 2020

FDA gives clearance to IND application for Calibr's 'switchable' CAR-T cell therapy

Calibr, the drug discovery and development division of Scripps Research, today announced that the U.S. Food and Drug Administration has given clearance to the Investigational New Drug (IND) application for Calibr's "switchable" CAR-T cell therapy, which is being evaluated for the treatment of certain cancers, including relapsed/refractory B-cell malignancies such as non-Hodgkin lymphoma and chronic lymphocytic leukemia.

3 Feb 2020

Experimental vaccine prevents infection of lung and nasal cavity

Researchers have found that viruses causing human respiratory infections called human metapneumovirus (HMPV) have a special ability to hide itself from the body’s immune system. This prevents the body from fighting the infection off. This very strategy has been used in development of a vaccine against HMPV say the researchers.

3 Feb 2020