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HemoShear announces milestone in development of predictive drug safety systems

HemoShear, LLC, a leading developer of human-relevant systems for drug development and discovery, today announced an important milestone in the development of systems that predict safety of new drugs and chemicals.

19 Jul 2013

Inovio's electroporation technology enhances ability of DNA therapy to stimulate blood vessel growth

Inovio Pharmaceuticals, Inc. announced today that the use of its proprietary electroporation technology significantly enhanced the ability of a DNA therapy to stimulate blood vessel growth, which may be beneficial for the treatment of critical limb ischemia and other forms of peripheral arterial disease.

18 Jul 2013

Poor sleep during pregnancy can disrupt immune processes and lead to lower birth weights

Poor sleep quality and quantity during pregnancy can disrupt normal immune processes and lead to lower birth weights and other complications, finds a University of Pittsburgh School of Medicine study published today in the journal Psychosomatic Medicine. Women with depression also are more likely than non-depressed women to suffer from disturbed sleep and to experience immune system disruption and adverse pregnancy outcomes.

18 Jul 2013

Spectrum researchers closer to predicting patients’ risk for heart attacks

We may be closer to predicting who is at risk for a heart attack, according to a recently published Spectrum Health study. Researchers with Spectrum Health's Frederik Meijer Heart & Vascular Institute used new imaging technology on patients being treated for heart attacks.

18 Jul 2013

Researchers discover new protein that encourages ‘bad’ blood vessel growth

The discovery of a protein that encourages blood vessel growth, and especially 'bad' blood vessels - the kind that characterise diseases as diverse as cancer, age-related macular degeneration and rheumatoid arthritis - has been reported in the journal Nature.

18 Jul 2013

Study shows CMEs can predict risk of cancer in type 2 diabetes patients

Certain chromosomal abnormalities of the preleukemic type appear to be over-represented in patients with type 2 diabetes (T2D) who are suffering from vascular complications. This finding may provide a partial explanation for the higher rates of cancer-related mortality observed among patients with this type of diabetes.

18 Jul 2013

Progress made in understanding Pulmonary Arterial Hypertension

The next step has been made into isolating the origin of cells linked to the progressive disorder Pulmonary Arterial Hypertension.

17 Jul 2013

Magnets could be used for directing stem cells, may help treat heart and vascular diseases

Magnets could be a tool for directing stem cells' healing powers to treat conditions such as heart disease or vascular disease.

17 Jul 2013

Standardized vascular health checks may improve health and cost-effectiveness outcomes

Archimedes Inc., a healthcare modeling company, today announced the results of a two-year long collaboration with Novo Nordisk A/S, a world leader in diabetes care, which evaluated the effects of standardized vascular health checks on expected health outcomes.

17 Jul 2013

Blood vessels grown from pluripotent stem cells able to function inside mice

Researchers at Johns Hopkins have coaxed stem cells into forming networks of new blood vessels in the laboratory, then successfully transplanted them into mice. The stem cells are made by reprogramming ordinary cells, so the new technique could potentially be used to make blood vessels genetically matched to individual patients and unlikely to be rejected by their immune systems, the investigators say.

17 Jul 2013

Alize Pharma initiates AZP-531 Phase I clinical trial for treatment of type 2 diabetes

Alize Pharma, a company specialized in the development of drugs for the treatment of metabolic diseases and rare diseases, announces today the launch of the first Phase I clinical trial for AZP-531, its unacylated ghrelin analog, in type 2 diabetes.

16 Jul 2013

Study explores mechanisms of chemotherapy-induced neurological side effects

Chemotherapy is one of the primary treatments for cancer. However, one of the most disturbing findings of recent studies of cancer survivors is the apparent prevalence of chemotherapy-associated adverse neurological effects, including vascular complications, seizures, mood disorders, cognitive dysfunctions, and peripheral neuropathies.

16 Jul 2013

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

These scientists under the leadership of Martin Bilban from the Clinical Institute of Laboratory Medicine at the MedUni Vienna discovered a chain of molecular mechanisms, which is kick-started by the formation of glucocorticoids.

12 Jul 2013

Protein that triggers blood clotting plays critical role in growth of pancreatic and breast cancer

A recently discovered form of the protein that triggers blood clotting plays a critical role in promoting the growth of metastatic pancreatic cancer and primary breast cancer, according to the cumulative findings from two new scientific manuscripts published online ahead of print in the International Journal of Cancer and PNAS (Proceedings of the National Academy of Sciences).

12 Jul 2013

Research shows proton pump inhibitors may cause cardiovascular problems

Drugs that help millions of people cope with acid reflux may also cause cardiovascular disease, report scientists from Houston Methodist Hospital and two other institutions in an upcoming issue of Circulation (now online). It is the first time researchers have shown how proton pump inhibitors, or PPIs, might cause cardiovascular problems.

11 Jul 2013

New approach delivers RNA drugs to silence malfunctioning genes

Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference.

10 Jul 2013

Researchers show cerebrovascular disease affecting blood circulation in brain associated with dementia

Researchers in the Perelman School of Medicine at the University of Pennsylvania found that, across a variety of neurodegenerative diseases, cerebrovascular disease affecting circulation of blood in the brain was significantly associated with dementia.

10 Jul 2013

Multiple pregnancies conceived after IVF associated with increased breast cancer risk

Women who give birth to multiple babies following IVF treatment are at a higher risk of breast cancer than those giving birth to singletons or who remain childless. Dutch investigators from the Omega study group said the explanation may not be the multiple pregnancy per se but a maternal trait related to a higher implantation potential and to breast cancer itself.

9 Jul 2013

Macrophages play essential role in production of progesterone hormone

New research from the University of Adelaide shows for the first time that immune cells known as macrophages are critical to fertility by creating a healthy hormone environment in the uterus.

9 Jul 2013

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Two drugs, telmisartan and valsartan, which are used to reduce blood pressure in people with diabetes, are associated with a lower risk of hospitalization for heart attack, stroke or heart failure, according to a study published in CMAJ (Canadian Medical Association Journal).

9 Jul 2013

Vascular News and Research

HemoShear announces milestone in development of predictive drug safety systems

Inovio's electroporation technology enhances ability of DNA therapy to stimulate blood vessel growth

Poor sleep during pregnancy can disrupt immune processes and lead to lower birth weights

Spectrum researchers closer to predicting patients’ risk for heart attacks

Researchers discover new protein that encourages ‘bad’ blood vessel growth

Study shows CMEs can predict risk of cancer in type 2 diabetes patients

Progress made in understanding Pulmonary Arterial Hypertension

Magnets could be used for directing stem cells, may help treat heart and vascular diseases

Standardized vascular health checks may improve health and cost-effectiveness outcomes

Blood vessels grown from pluripotent stem cells able to function inside mice

Alize Pharma initiates AZP-531 Phase I clinical trial for treatment of type 2 diabetes

Study explores mechanisms of chemotherapy-induced neurological side effects

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

Protein that triggers blood clotting plays critical role in growth of pancreatic and breast cancer

Research shows proton pump inhibitors may cause cardiovascular problems

New approach delivers RNA drugs to silence malfunctioning genes

Researchers show cerebrovascular disease affecting blood circulation in brain associated with dementia

Multiple pregnancies conceived after IVF associated with increased breast cancer risk

Macrophages play essential role in production of progesterone hormone

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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