Immune Response News and Research

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Yale researchers take important step toward curbing the threat posed by tsetse fly

When an infected tsetse fly bites humans or other mammals to feed on their blood, microscopic parasites (African trypanosomes) in the fly's saliva are transferred. The unfortunate recipient of the bite, once infected, often faces severe health consequences, even death.

3 Feb 2020

New combination treatment could help fight advanced melanoma

A study by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that using an immunotherapy drug called NKTR-214, also known as bempegaldesleukin, in combination with an infusion of anti-tumor immune cells, or T cells, may produce a stronger immune response that could help fight advanced melanoma.

31 Jan 2020

Multimodal analysis of tumors could give new insights into treating cancer patients

Melding the genetic and cellular analysis of tumors with how they appear in medical images could give physicians and other cancer therapy specialists new insights into how to best treat patients, especially those with brain cancer, according to a new study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

31 Jan 2020

Modified form of poliovirus shows potential as cancer vaccine in animal studies

A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine.

31 Jan 2020

WPI researcher awarded grant for research into leading cause of aortic valve dysfunction

Worcester Polytechnic Institute researcher Kristen Billiar has been awarded a $154,000 grant from the American Heart Association to determine how cell death leads to calcium deposits in heart tissue that cause aortic valves to fail.

30 Jan 2020

Scientists reveal clinical features of Wuhan coronavirus patients

The Wuhan coronavirus, or the 2019-nCoV, which originated in Wuhan City in Hubei province infected more than 7,700 people with the death toll topping more than 170. China reports 38 deaths in just 24 hours, making the outbreak one of the deadliest ones the country has faced.

30 Jan 2020

Bavarian research network aims to develop new approaches against multi-resistant pathogens

Developing fundamental new approaches against multi-resistant pathogens is the aim of the new Bavarian research network called New Strategies Against Multi-Resistant Pathogens by Means of Digital Networking - bayresq.net.

29 Jan 2020

Avacta demonstrates initial proof-of-concept for TMAC drug conjugates in pre-clinical study

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that it has demonstrated initial proof-of-concept for its proprietary new class of drug conjugate, TMAC, in a pre-clinical animal model of cancer.

From Avacta Life Sciences Ltd. 28 Jan 2020

BCG vaccine formulations vary widely in their characteristics, study shows

Each year, more than 100 million newborns around the world receive vaccinations against Mycobacterium tuberculosis, or TB, which infects about one-quarter of the world's population.

28 Jan 2020

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

An international research team which includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying the genes and proteins involved in the response to certain harmful bacteria.

28 Jan 2020

Specific gut microbes have the capacity to affect normal skeletal growth and maturation

Microbes are often seen as pathogens that cause disease, but the picture is actually more complex than that limited view.

28 Jan 2020

What parents need to know about the HPV vaccine

The vaccine that prevents infection from human papillomavirus (HPV) is nothing short of a medical marvel.

28 Jan 2020

First glioblastoma patient treated with genetically modified poliovirus at UH

University Hospitals Seidman Cancer Center treated its first patient in a new clinical trial to validate the groundbreaking effects of the poliovirus on glioblastoma, a deadly Grade IV cancer of the brain.

24 Jan 2020

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

Toxoplasma gondii is best known as the parasite that may lurk in a cat's litter box. Nearly a third of the world's population is believed to live with a chronic Toxoplasma infection.

24 Jan 2020

Iron overload, variant gene and malaria resistance linked in African study

A new study shows that a rare genetic mutation giving rise to a variant of the TP53 gene called P47S causes several linked biological processes.

24 Jan 2020

New study gives hope for potentially developing a cure for HIV

HIV latency is considered one of the biggest challenges to developing a cure for the virus.

23 Jan 2020

Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

New findings can help explain why immune systems are not found in many bacteria

New findings from University of Exeter researchers reveal how bacterial immune systems can be harmful for their hosts and explain why they are not found in many bacteria.

22 Jan 2020

Instagramers still love vaping despite FDA’s anti-vaping slogans

A unique study posted in the journal Frontiers in Communication in January 2020 reports that of 200,000 posts on Instagram, the number of hashtags favoring vaping or e-cigarette use outnumbers the number of those against it by an astonishing 10,000 times. Vaping refers to the use of flavored juices, often containing nicotine, in electrically operated heating devices that allow the user to inhale the fumes of the heated juice and exhale it, similar to smoking a conventional cigarette.

21 Jan 2020

Researchers develop novel technology to produce cheaper, longer-lasting vaccines

A new method to produce vaccines that have a longer shelf-life, are cheaper and can be stored without the need for cooling is being presented in the open access journal BMC Biotechnology.

21 Jan 2020

Immune Response News and Research

Yale researchers take important step toward curbing the threat posed by tsetse fly

New combination treatment could help fight advanced melanoma

Multimodal analysis of tumors could give new insights into treating cancer patients

Modified form of poliovirus shows potential as cancer vaccine in animal studies

WPI researcher awarded grant for research into leading cause of aortic valve dysfunction

Scientists reveal clinical features of Wuhan coronavirus patients

Bavarian research network aims to develop new approaches against multi-resistant pathogens

Avacta demonstrates initial proof-of-concept for TMAC drug conjugates in pre-clinical study

BCG vaccine formulations vary widely in their characteristics, study shows

Scientists 'knock out' gene in myeloid cells to create listeriosis-immune mice

Specific gut microbes have the capacity to affect normal skeletal growth and maturation

What parents need to know about the HPV vaccine

First glioblastoma patient treated with genetically modified poliovirus at UH

T. gondii parasite employs a sophisticated manipulation to suppress host's immune response

Iron overload, variant gene and malaria resistance linked in African study

New study gives hope for potentially developing a cure for HIV

Scientists reverse HIV latency, take major scientific step toward curative therapies

New findings can help explain why immune systems are not found in many bacteria

Instagramers still love vaping despite FDA’s anti-vaping slogans

Researchers develop novel technology to produce cheaper, longer-lasting vaccines

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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