Immune Response News and Research

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Avacta and Daewoong Pharmaceutical announce joint venture to develop novel cell and gene therapies

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, and Daewoong Pharmaceutical Co. Ltd., a leading Korean pharmaceutical company, are pleased to announce that they have agreed to establish a joint venture in South Korea, and to enter a collaboration and license agreement for the joint venture to develop the next generation of cell and gene therapies incorporating Affimer proteins to enhance the immune-modulatory effects.

From Avacta Life Sciences Ltd. 9 Jan 2020

Scientists discover how dying cells prevent dangerous immune reactions

Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues.

8 Jan 2020

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Scientists from Trinity College Dublin have discovered both how TB puts the brakes on our immune engines and how we can kick-start those engines back into gear - providing hope that improved treatment options could soon be on the horizon.

8 Jan 2020

Research adds definitive evidence about how the body's earliest immune cells are formed

One day the advance could lead to a patient's own skin cells being used to produce new cells for cancer immunotherapy or to test autoimmune disease interventions.

8 Jan 2020

Growing influenza vaccines inside chicken eggs can make them less effective, say some experts

Flu season is underway in the Northern Hemisphere, sickening millions of people and in rare cases, causing hospitalization or death. The best prevention is a flu shot, but it's not unusual for these vaccines to be less effective than intended. Some researchers suspect that the common practice of producing vaccines in chicken eggs could be partially to blame, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society.

8 Jan 2020

Extremely low concentrations of acetic acid could alter cellular processes in rice blast fungus

All living organisms respond and adapt to changes in their environment. These responses are sometimes so significant that they cause alterations in the internal metabolic cycles of the organism--a process called "metabolic switching." For example, rice blast fungus--a pathogenic fungal species that causes the "rice blast" infection in rice crops--switches to the "glyoxylate cycle" when the nutrient source starts to deplete.

8 Jan 2020

Airway Therapeutics receives funding to advance BPD treatment

Airway Therapeutics, Inc., a biopharmaceutical company developing a new class of biologics to break the injury cycle of inflammation for patients with respiratory and inflammatory diseases, announced today the closing of a $15.5 million oversubscribed Series C financing round.

8 Jan 2020

New nanotech technique fights advanced-stage sepsis

Scientists have found a novel approach using nanotechnology that can fight late-stage sepsis.

8 Jan 2020

Bacterial exposure is a potential environmental risk factor in developing coeliac disease

Bacterial exposure has been identified as a potential environmental risk factor in developing coeliac disease, a hereditary autoimmune-like condition that affects about one in 70 Australians.

8 Jan 2020

Study reveals new mechanism that controls the causes of stomach disease

Infectious diseases triggered by bacteria and other microbes are the most frequent cause of human mortality across the globe.

8 Jan 2020

Classroom activities pose low risk of harmful gluten exposure in children with celiac disease

Common classroom activities – such as playing with Play-Doh or uncooked pasta – have little or no potential to cause harmful gluten exposure in children with celiac disease, reports a study in the Journal of Pediatric Gastroenterology and Nutrition.

7 Jan 2020

Immune cell discovery could hold the key to effective therapies against cancer

Scientists at UCL have identified how a subset of immune cells are activated to kill cancerous cells, a finding in mice which could hold the key to new powerful therapies against cancer.

7 Jan 2020

Can FDA-approved flu shots be repurposed as treatments for cancer?

Changing the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and clinical studies including the most recent use of checkpoint inhibitory antibodies.

7 Jan 2020

Temperature fluctuations could give early indications of graft-versus-host disease

By continuously monitoring the body temperature of mice that had undergone bone-marrow transplants, researchers were able to detect early warning signs of graft-versus-host disease - a dangerous, sometimes deadly response of the transplanted immune system - in a simple, non-invasive way.

6 Jan 2020

ART may not be completely effective in restoring immune protection, study suggests

A study led by researchers from SUNY Downstate Health Sciences University and Oregon Health & Science University, published in the Journal of Infectious Diseases, showed that, despite successful antiretroviral therapy, antigen specific memory to vaccinations that occurred before HIV infection did not recover, even after immune reconstitution.

6 Jan 2020

Bile acids could also play a role in immunity and inflammation

Could bile acids--the fat-dissolving juices churned out by the liver and gallbladder--also play a role in immunity and inflammation?

3 Jan 2020

Researchers study new immunogenic properties of already existing anti-cancer drugs

The world scientific community is waging a difficult and prolonged war on cancer. New research in the field of immunogenic cell death can extend the area of drugs application and ensure patients' protection from relapse after therapy.

3 Jan 2020

Researchers discover how c-Cbl protein modulates tumor growth

Immune checkpoints are surface proteins that cancer cells use to evade immune response. These surface proteins are critical for cancer cell growth and drugs targeting these proteins have revolutionized the management of patients with a wide array of cancers.

2 Jan 2020

Intravenous BCG vaccine provides greater protection against tuberculosis

Researchers have found that the BCG vaccine is more efficacious in the prevention of TB when administered intravenously.

2 Jan 2020

Study helps explain why previous attempts to develop a staph vaccine have failed

Staph bacteria, the leading cause of potentially dangerous skin infections, are most feared for the drug-resistant strains that have become a serious threat to public health.

26 Dec 2019

Immune Response News and Research

Avacta and Daewoong Pharmaceutical announce joint venture to develop novel cell and gene therapies

Scientists discover how dying cells prevent dangerous immune reactions

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Research adds definitive evidence about how the body's earliest immune cells are formed

Growing influenza vaccines inside chicken eggs can make them less effective, say some experts

Extremely low concentrations of acetic acid could alter cellular processes in rice blast fungus

Airway Therapeutics receives funding to advance BPD treatment

New nanotech technique fights advanced-stage sepsis

Bacterial exposure is a potential environmental risk factor in developing coeliac disease

Study reveals new mechanism that controls the causes of stomach disease

Classroom activities pose low risk of harmful gluten exposure in children with celiac disease

Immune cell discovery could hold the key to effective therapies against cancer

Can FDA-approved flu shots be repurposed as treatments for cancer?

Temperature fluctuations could give early indications of graft-versus-host disease

ART may not be completely effective in restoring immune protection, study suggests

Bile acids could also play a role in immunity and inflammation

Researchers study new immunogenic properties of already existing anti-cancer drugs

Researchers discover how c-Cbl protein modulates tumor growth

Intravenous BCG vaccine provides greater protection against tuberculosis

Study helps explain why previous attempts to develop a staph vaccine have failed

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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