Vascular News and Research

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Omega-3 fatty acids may reduce inflammation associated with cardiovascular procedures

MD-Procedures like angioplasty, stenting and bypass surgery may save lives, but they also cause excessive inflammation and scarring, which ultimately can lead to permanent disability and even death.

31 May 2013

Ragweed allergy sublingual immunotherapy: an interview with Dr. Peter Creticos, Johns Hopkins University School of Medicine

Ragweed is a dominant seasonal allergen in North America (~26% of US and North American population is allergic to this noxious weed which pollinates from early August to early October).

31 May 2013

Comprehensive analyses of the benefits and risks of NSAIDs

Charles H. Hennekens, MD, DrPH, the first Sir Richard Doll professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University has published in the current issue of The Lancet the most comprehensive analyses of the benefits and risks of non-steroidal anti-inflammatory drugs, which include cyclo-oxygenase-2 inhibitors (coxibs).

31 May 2013

Endovascular stroke therapy should be limited to use within clinical trials, say physicians

Devices snaked into the brain artery of a patient experiencing a stroke that either snatch and remove the offending clot or pump a dissolving drug into the blockage should primarily be used within a clinical trial setting, say a team of vascular neurologists at Mayo Clinic in Florida.

30 May 2013

Strengthening miniaturized titanium-based medical devices: an interview with Dr Masaru Rao, University of California, Riverside

While titanium is used widely for more conventional macro-scale medical devices (e.g. hip implants, dental implants, and cardiac pacemakers), its use for micro- and nano-scale devices has been limited thus far.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

New HELIO dock system acts as anchor to stabilise SAPIEN XT valve for aortic insufficiency patients

A new investigational device - the Helio System (TF-FA) - being developed for use with the Sapien XT Transcatheter Heart Valve was successfully deployed in all four patients in a small, first-in-human feasibility study of its use in high-risk aortic insufficiency reported at EuroPCR 2013.

27 May 2013

Transcatheter aortic valve implantation is safe and effective in Asian patients

Transcatheter aortic valve implantation (TAVI) is effective and safe in Asian patients, according to early experience based on first results from a multicentre Asian registry reported at EuroPCR 2013.

27 May 2013

OrbusNeich introduces COMBO Dual Therapy Stent

OrbusNeich today launched the world's first dual therapy stent – the COMBO Dual Therapy Stent – to address the challenges of delayed healing of the coronary artery associated with monotherapy drug eluting stents, the current standard of care for the treatment of coronary artery disease.

27 May 2013

OPKO reports more than 50% enrollment in phase 3 trial of Rayaldy for treatment of secondary hyperparathyroidism

OPKO Health, Inc., has surpassed 50% enrollment in the first phase 3 trial of RayaldyTM to treat patients with secondary hyperparathyroidism (SHPT), stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

24 May 2013

Heart disease signs in newborns: an interview with Dr Michael Skilton, University of Sydney

Thickening of the walls of the main arteries is the best indicator of poor cardiovascular health in healthy young children.

23 May 2013

Findings suggest that a prosaposin-based drug could block metastasis spread

By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer.

22 May 2013

Diachisis can occur during subacute phase of ischemic stroke, find USF researchers

While the effects of acute stroke have been widely studied, brain damage during the subacute phase of stroke has been a neglected area of research. Now, a new study by the University of South Florida reports that within a week of a stroke caused by a blood clot in one side of the brain, the opposite side of the brain shows signs of microvascular injury.

21 May 2013

Study: VEGF inhibitor appears to improve glaucoma surgical outcomes

The most common cause of failure after glaucoma surgery is scarring at the surgical site, so researchers are actively looking for ways to minimize or prevent scar formation. Previous work had suggested that vascular endothelial growth factor (VEGF) activates fibrosis, whereas VEGF inhibition results in reduced scar formation and better surgical results.

18 May 2013

Newer class of diabetes medications may also improve cardiovascular health, researchers report

A newer class of medications used to control blood sugar levels in type 2 diabetics may also improve cardiovascular health, researchers from The Ohio State University Wexner Medical Center reported in a new meta-analysis presented yesterday at the American Society of Hypertension's Annual Scientific Meeting and Exposition.

17 May 2013

Researchers study effects of exergaming on children

Levels of physical inactivity and obesity are very high in children, with fewer than 50% of primary school-aged boys and fewer than 28% of girls meeting the minimum levels of physical activity required to maintain health.

17 May 2013

New research reveals how endothelium maintains highly efficient barrier function

The endothelium, the cellular layer lining the body's blood vessels, is extremely resilient. Measuring just a few hundred nanometers in thickness, this super-tenuous structure routinely withstands blood flow, hydrostatic pressure, stretch and tissue compression to create a unique and highly dynamic barrier that maintains the organization necessary to partition tissues from the body's circulatory system.

17 May 2013

Research: People with skin cancer may be less likely to develop Alzheimer's disease

People who have skin cancer may be less likely to develop Alzheimer's disease, according to new research published in the May 15, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. The link does not apply to melanoma, a less common but more aggressive type of skin cancer.

17 May 2013

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body.

17 May 2013

Research sheds new light on occupation-specific rehabilitation

After cardiac surgery, should a farmer and an attorney take the same physical test to be found fit for work? They do now. But new research from Jenny Adams, PhD, at Baylor Health Care System's Baylor Hamilton Heart and Vascular Hospital, could change that.

16 May 2013

Vascular News and Research

Omega-3 fatty acids may reduce inflammation associated with cardiovascular procedures

Ragweed allergy sublingual immunotherapy: an interview with Dr. Peter Creticos, Johns Hopkins University School of Medicine

Comprehensive analyses of the benefits and risks of NSAIDs

Endovascular stroke therapy should be limited to use within clinical trials, say physicians

Strengthening miniaturized titanium-based medical devices: an interview with Dr Masaru Rao, University of California, Riverside

Transplantation of human stem cells improves muscle function in rats used to model ALS

New HELIO dock system acts as anchor to stabilise SAPIEN XT valve for aortic insufficiency patients

Transcatheter aortic valve implantation is safe and effective in Asian patients

OrbusNeich introduces COMBO Dual Therapy Stent

OPKO reports more than 50% enrollment in phase 3 trial of Rayaldy for treatment of secondary hyperparathyroidism

Heart disease signs in newborns: an interview with Dr Michael Skilton, University of Sydney

Findings suggest that a prosaposin-based drug could block metastasis spread

Diachisis can occur during subacute phase of ischemic stroke, find USF researchers

Study: VEGF inhibitor appears to improve glaucoma surgical outcomes

Newer class of diabetes medications may also improve cardiovascular health, researchers report

Researchers study effects of exergaming on children

New research reveals how endothelium maintains highly efficient barrier function

Research: People with skin cancer may be less likely to develop Alzheimer's disease

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

Research sheds new light on occupation-specific rehabilitation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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