Immune Response News and Research

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Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Researchers have vaccinated mice against the Zika virus, whilst others have discovered a new platform for flavivirus vaccines.

12 Dec 2019

Immune cells repair damaged gut in children with IBD

According to a new study published in the journal Gastroenterology, immune cells of a certain kind which regulate inflammatory processes and even help restore normal gut function after inflammation could be of great use to treat children with inflammatory bowel disease (IBD).

11 Dec 2019

New approach to alter intestinal microbiota and protect against inflammatory diseases

Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to cause inflammation and thus protecting against an array of chronic inflammatory diseases, according to a new study by the Institute for Biomedical Sciences and the Neuroscience Institute at Georgia State University.

11 Dec 2019

Yeasts derived from food can reduce multi-drug resistant fungal infections

A study by researchers in the United States and India has shown that probiotic yeasts derived from food are able to reduce the virulence of, and even prevent infections by, several types of fungi that are responsible for life-threatening infections in hospitalized and immune-compromised individuals, including the multi-drug resistant Candida auris, which was recently listed as an urgent threat by the U.S. Centers for Disease Control in its 2019 Antibiotic Resistance Threats report.

10 Dec 2019

Influenza IMPRINT Cohort study awarded $9.1 million boost from Open Philanthropy Project

A $30 million Influenza IMPRINT Cohort study led by Cincinnati Children's has been awarded a $9.1 million boost from the Open Philanthropy Project.

10 Dec 2019

Mitochondrial dysfunction may underlie prolonged muscle weakness after sepsis

Damage to energy-producing mitochondria may underlie prolonged muscle weakness following a sepsis-like condition in mice, according to a new study published today in eLife.

10 Dec 2019

Common antibiotic appears to boost the effect of radiation on tumor cells

The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy.

9 Dec 2019

'Achilles' heel' of deadly superbug identified

A deadly superbug that infects an estimated 54,500 Americans a year has a secret weapon, a protein, that allows it to defy antibiotic treatment and immune system attacks.

9 Dec 2019

New software tool uses AI to recognize cancer cells from digital pathology images

UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images - giving clinicians a powerful way of predicting patient outcomes.

9 Dec 2019

Malaysia announces first case of polio in the country for 27 years

Malaysia health officials have reported the first case of polio in the country for 27 years.

9 Dec 2019

New approach to broadly acting, highly effective HIV vaccine

Researchers have reported a major advance in the creation of a successful HIV vaccine that is not produced by the host animal.

9 Dec 2019

Piglet study shows probiotics and prebiotics work differently in girls and boys

The team from the Universities of Bristol and Reading found that 28-day old piglets produced very different levels of immune cells, antibodies and other immune-associated molecules depending on their sex, contradicting previous evidence suggesting that the difference in immunity begins during puberty.

9 Dec 2019

Researchers discover potent next generation of drugs to fight leukemia and lymphoma

UT Health San Antonio researchers, working with collaborators at the University of Florida, have discovered a safe and potent next generation of drugs to fight multiple types of leukemia and lymphoma in adults and children.

6 Dec 2019

Breakthrough research develops novel vaccine poised to cure peanut allergies

Peanut allergies could become a thing of the past as breakthrough research from the University of South Australia develops a radically novel vaccination that's poised to cure the potentially life threatening condition.

6 Dec 2019

Researchers confirm two new prognostic markers for triple negative breast cancer

Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide.

5 Dec 2019

Prenatal and early life exposure to air pollutants associated with toddler allergies

A new article in Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology shows a significant association between multiple prenatal and early life exposures to indoor pollutants and the degree of allergic sensitivity in 2-year-olds.

5 Dec 2019

Young patients with IBD have increased risk of severe viral infections

Young patients with inflammatory bowel disease are five times more likely than the general population to develop viral infections that can lead to hospitalization or permanent organ damage, a new study published in the UEG Journal has found.

5 Dec 2019

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

Investigators in the Blood and Marrow Transplant Program at Rutgers Cancer Institute of New Jersey compared outcomes for patients having undergone allogeneic stem cell transplant when post-transplant cyclophosphamide (PCy, a type of chemotherapy) was added as part of standard treatment to prevent disease through an immune response (immunoprophylaxis) than if this standard treatment was given alone.

5 Dec 2019

New model can help study the mechanisms of bone metastasis, tumor immune response

The Research Team reports the establishment of B6Ca P, an allograft tumor line from a Hi-Myc transgenic mouse that had been backcrossed onto C57BL/6J background.

4 Dec 2019

Transitional T cells could help improve cancer immunotherapy

In chronic viral infections and cancer, T cell dysfunction is sure to be observed. A new study to be published in the journal Immunity shows that before these cells are completely exhausted, there is a transitory stage in which some cells are present with features that are characteristic of neither the stem-like T cells nor the mature but exhausted T cells.

4 Dec 2019

Immune Response News and Research

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Immune cells repair damaged gut in children with IBD

New approach to alter intestinal microbiota and protect against inflammatory diseases

Yeasts derived from food can reduce multi-drug resistant fungal infections

Influenza IMPRINT Cohort study awarded $9.1 million boost from Open Philanthropy Project

Mitochondrial dysfunction may underlie prolonged muscle weakness after sepsis

Common antibiotic appears to boost the effect of radiation on tumor cells

'Achilles' heel' of deadly superbug identified

New software tool uses AI to recognize cancer cells from digital pathology images

Malaysia announces first case of polio in the country for 27 years

New approach to broadly acting, highly effective HIV vaccine

Piglet study shows probiotics and prebiotics work differently in girls and boys

Researchers discover potent next generation of drugs to fight leukemia and lymphoma

Breakthrough research develops novel vaccine poised to cure peanut allergies

Researchers confirm two new prognostic markers for triple negative breast cancer

Prenatal and early life exposure to air pollutants associated with toddler allergies

Young patients with IBD have increased risk of severe viral infections

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

New model can help study the mechanisms of bone metastasis, tumor immune response

Transitional T cells could help improve cancer immunotherapy

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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