Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Nile completes dosing in Part B of cenderitide Phase I study for ADHF

Nile Therapeutics, Inc., a biopharmaceutical company that develops novel therapeutics for heart failure patients, today announced that it has completed dosing the first patient in Part B of the ongoing Phase I study.

27 Jun 2011

Redefinition of cardiac hypertrophy term needed

The European Society of Cardiology (ESC) Working Group on Myocardial Function is calling for a redefinition of the term cardiac hypertrophy which is currently used to describe changes to the morphology (structure) of the heart. Instead the position paper, published online today in the European Journal of Heart Failure, suggests that use of the general term myocardial remodelling should be preferred.

27 Jun 2011

New guide indicates when and how genetic testing is useful for inherited cardiac conditions

While genetic inheritance is known to play a role in the multifactorial development of most diseases of the heart, there are also a number of clearly diagnosed cardiac conditions which owe their development to quite specific genetic abnormalities. When these genetic disorders affect the integrity of the heart's muscle they are known as a "cardiomyopathy"; when the disorder affects the heart's "excitability", it is known as a "channelopathy".

27 Jun 2011

New data from JANUMET clinical study on type 2 diabetes presented at ADA 2011

In a new post-hoc analysis based on the American Association of Clinical Endocrinologists (AACE/ACE) diabetes algorithm presented at the American Diabetes Association (ADA) 71st Annual Scientific Sessions, significantly more patients with type 2 diabetes treated with JANUMET-tablets achieved blood sugar goals after 18 weeks compared to metformin as initial therapy.

27 Jun 2011

Anticholinergic medications linked to risk of cognitive impairment, death in older population

A large, long-term study confirms that medications with anticholinergic activity, which include many drugs frequently taken by older adults, cause cognitive impairment. The research is also the first to identify a possible link between these drugs - which include over-the-counter and prescription sleep aids and incontinence treatments - and risk of death.

27 Jun 2011

Mortality, morbidity rates linked with AF remain 'unacceptably high' despite new treatments

Despite recent advances in the treatment of heart rhythm disturbances, mortality and morbidity rates associated with atrial fibrillation (AF) remain "unacceptably high", according to a new report.

27 Jun 2011

BIOTRONIK to introduce Lumax DX system for complete atrial arrhythmia diagnosis

BIOTRONIK SE & Co. KG, a worldwide leader in manufacturing cardiac medical devices, announced today that the innovative new Lumax 540 VR-T DX single-chamber implantable cardiac defibrillator (ICD) and Linoxsmart S DX cardiac lead system will be launched this coming week at the EHRA EUROPACE electrophysiology congress in Madrid, Spain.

24 Jun 2011

Twelve institutions receive NPCRC and American Cancer Society grants for palliative care research

The American Cancer Society and the National Palliative Care Research Center (NPCRC) are awarding $2 million in research grants to researchers at 12 institutions for studies aimed at reducing suffering for seriously ill patients and their family caregivers.

22 Jun 2011

Pycnogenol, CoQ10 combination boost heart function

A recent study published in Panminerva Medica reveals that a Pycnogenol and Coenzyme Q10 combination taken by stable heart failure patients as an adjunct to medical treatment naturally strengthens the heart, increasing the blood volume ejected with each beat.

22 Jun 2011

Genetic mutation linked to peripartum cardiomyopathy during pregnancy

Researchers at the Intermountain Medical Center Heart Institute in Salt Lake City have identified the first genetic mutation ever associated with a mysterious and potentially devastating form of heart disease that affects women in the final weeks of pregnancy or the first few months after delivery.

22 Jun 2011

Exercise helps overcome side effects of cancer, improves survival

Brain cancer patients who are able to exercise live significantly longer than sedentary patients, scientists at the Duke Cancer Institute report.

22 Jun 2011

Palatin receives U.S. patent titled ‘Amino Acid Surrogates for Peptidic Constructs'

Palatin Technologies, Inc. announced today that the U.S. Patent and Trademark Office issued U.S. Patent No. 7,964,181, titled "Amino Acid Surrogates for Peptidic Constructs."

22 Jun 2011

Amylin to present data on investigational diabetes drug candidates at ADA annual meeting

Amylin Pharmaceuticals, Inc. today announced that the Company will present data for its two first-in-class diabetes drugs, BYETTA injection and SYMLIN injection, and its investigational diabetes drug candidates BYDUREON and exenatide once monthly at the 71st Scientific Sessions of the American Diabetes Association (ADA) being held in San Diego, CA from June 24 to June 28.

21 Jun 2011

Neovasc first quarter revenues increase 10% to $1,169,920

Neovasc Inc., today announced financial results for the three months ended March 31, 2011 and advances in its product development programs.

20 Jun 2011

Study: Abdominal debrancing with aortic stent grafts linked to high early mortality

The clinical data from 167 patients who underwent abdominal debrancing combined with aortic stent grafts (ADSG) at 12 centers in North America from1999-2010 were released today at the 65th Vascular Annual Meeting® presented by the Society for Vascular Surgery.

20 Jun 2011

Study evaluates impact of medication adherence, comorbidity on workforce productivity

A new study suggests that while medication adherence is a critical element in reducing the impact of illness, employers should view it as just one of multiple components that are needed in strategic employee disease-management initiatives.

18 Jun 2011

First artificial lung transplantation in toddler performed at St. Louis Children's Hospital

Two-year-old Owen Stark came to St. Louis Children's Hospital in the summer of 2010 near death from heart failure and dangerously high blood pressure in his lungs.

17 Jun 2011

CTI announces positive results from Phase I-II pixantrone combination study against INHL

Cell Therapeutics, Inc. announced the publication of results posted in the online journal of Cancer of a Phase I-II study that evaluated the safety and efficacy of pixantrone when used in combination with fludarabine, dexamethasone and rituximab replacing mitoxantrone in the standard FND-R regimen with FPD-R among 28 patients with relapsed or refractory indolent non-Hodgkin's lymphoma.

17 Jun 2011

Cholesterol-lowering statins reduce rate of mortality and cardiovascular events

Over the long term, treatment with cholesterol-lowering statins reduces the rate of mortality and cardiovascular events such as heart attack, for people with and without heart disease. Still, it is unclear whether these drugs take effect rapidly when the risk of these dire events is highest.

15 Jun 2011

CerebralRx launches FitNeS vagus nerve stimulation system for treating epilepsy

CerebralRx, a newly formed spin-off of implantable neuromodulation systems developer BioControl Medical, has announced market entry with the launch of its FitNeS vagus nerve stimulation system.

14 Jun 2011

Heart Failure News and Research

Further Reading

Nile completes dosing in Part B of cenderitide Phase I study for ADHF

Redefinition of cardiac hypertrophy term needed

New guide indicates when and how genetic testing is useful for inherited cardiac conditions

New data from JANUMET clinical study on type 2 diabetes presented at ADA 2011

Anticholinergic medications linked to risk of cognitive impairment, death in older population

Mortality, morbidity rates linked with AF remain 'unacceptably high' despite new treatments

BIOTRONIK to introduce Lumax DX system for complete atrial arrhythmia diagnosis

Twelve institutions receive NPCRC and American Cancer Society grants for palliative care research

Pycnogenol, CoQ10 combination boost heart function

Genetic mutation linked to peripartum cardiomyopathy during pregnancy

Exercise helps overcome side effects of cancer, improves survival

Palatin receives U.S. patent titled ‘Amino Acid Surrogates for Peptidic Constructs'

Amylin to present data on investigational diabetes drug candidates at ADA annual meeting

Neovasc first quarter revenues increase 10% to $1,169,920

Study: Abdominal debrancing with aortic stent grafts linked to high early mortality

Study evaluates impact of medication adherence, comorbidity on workforce productivity

First artificial lung transplantation in toddler performed at St. Louis Children's Hospital

CTI announces positive results from Phase I-II pixantrone combination study against INHL

Cholesterol-lowering statins reduce rate of mortality and cardiovascular events

CerebralRx launches FitNeS vagus nerve stimulation system for treating epilepsy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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