Immune Response News and Research

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New method for discovering potential cancer-treating compounds

A new study published in the journal Cell Reports reports a novel method by which antitumor drugs that focus on reawakening exhausted immune cells called cytotoxic T cells against cancer can be quickly identified. This could help treat a large subset of cancers that thrive because of their ability to suppress antitumor activity in T cells.

4 Dec 2019

Dynamics of crucial immune system proteins revealed

Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. Exactly how these proteins carry out their crucial functions has not been well understood.

3 Dec 2019

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Fueling exploration by investigators who collaborate under a research consortium partnership as recognized by the National Cancer Institute, between Rutgers Cancer Institute of New Jersey and Princeton University, the GO2 Foundation for Lung Cancer has awarded $250,000 toward the identification and development of novel strategies to address treatment resistance in non-small cell lung cancer.

3 Dec 2019

New findings may help researchers leverage ERAP1 to fight cancer

In a paper published in the Journal of Biological Chemistry, University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.

3 Dec 2019

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

The growing trend of implementing immunotherapy into oncology has resulted in various new therapeutic cancer treatments utilizing antibodies.

From Sartorius 3 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

Study: Spleen and gut lymph nodes may serve as reservoir replication sites for HIV virus

An international team led by Professor Jerome Estaquier from Universite Laval's Faculty of Medicine and the CHU de Quebec-Universite Laval Research Center may have discovered where in the body HIV takes refuge during antiretroviral treatment.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

Study suggests two new approaches against bone metastases from prostate cancer

When prostate cancer spreads, it most often spreads to bone. And while the 5-year survival rate for prostate cancer that has not spread is nearly 100 percent, once the disease reaches bone, the 5-year survival rate is only 29 percent.

2 Dec 2019

Research uncovers mechanism that triggers inflammatory process by Mayaro virus

The mechanism by which defense cells respond to infection by Mayaro virus has been described by a team affiliated with the Center for Research on Inflammatory Diseases - CRID in an article published in the journal PLOS Pathogens.

2 Dec 2019

Strong beers that contain gut-friendly bacteria may help fight obesity

Drinking a strong type of beer, particularly a Belgian one, can help combat obesity, promote a good night’s sleep, and may help you live longer, a new study found.

2 Dec 2019

Link found between the gut microbiome, host genome, and RA in Japanese population

One of the most astounding discoveries of recent times is just how much influence gut bacteria have on our health and well-being.

2 Dec 2019

Stem cells do help restore heart function – but in a different way

A new study published in the journal Nature shows that stem cells do work well to repair the damaged heart – but in an entirely different manner than was originally supposed. The study shows that stem cells, whether living or dead, when injected into the area of damage in the heart in mice, activate an intense acute inflammation. This triggers the classic wound healing response which finally results in the partial or complete recovery of mechanical function of the injured area.

28 Nov 2019

New vaccine against bovine TB

A new study published in the journal Scientific Reports says that for the first time a vaccine has been created against bovine tuberculosis that can be given without affecting the ability to diagnose tuberculosis later using the PPD skin test.

28 Nov 2019

New compound may enhance dengue vaccine efficacy by simulating amino acid deficiency

A new study published in the journal Science Signaling on November 26, 2019, describes a mouse experiment, in which the immune response to the dengue vaccine was boosted when the mice were first given halofuginone, a plant compound that is well known to herbalists.

27 Nov 2019

Scientists sheds light on small protein and its role in immune response

The immune system is the body’s defense against disease-causing pathogens. It works by warding off disease and potentially-damaging foreign bodies. Now, a team of researchers have developed a new method to shed light on the basic defense mechanism of the immune system.

27 Nov 2019

Sanitization error might possibly have exposed hundreds to HIV at Indiana hospital

An Indiana hospital is in the news for all the wrong reasons. An accidental failure by one of the seven sterilization technicians working at the hospital was recently discovered. The technician failed to carry out a single step in a protocol concerning the sanitization of surgical equipment at Goshen Hospital, over a period from April 1 to September 30.

26 Nov 2019

Attacking HIV at the source

A new study published on November 26, 2019, in the journal Cell Reports, details a new discovery that may help avert HIV infection right at the start. The virus is known to take a long time to infect a person, and the scientists say they have found a period during which it can be weakened or killed, in the very first hours after it has entered a host. They call this the window of vulnerability.

26 Nov 2019

Research could help design better flu vaccines

Each year millions of Americans become sick with the flu, hundreds of thousands are hospitalized and tens of thousands die. Getting the flu shot can reduce the chances of infection. But, at best, the vaccine is only effective 40% to 60% of the time, according to the CDC.

26 Nov 2019

Looking for the source: new routes for allergy treatment

A new multinational study has reported a very full account of the B lymphocytes that produce group E antibodies, also called IgE (Immunoglobulin E), that are behind allergic reactions, which are common in up to a third of the world’s population.

26 Nov 2019