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Blood vessels play an important role in preventing spread of tumour cells

A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University in Sweden in a study published in the scientific periodical The Journal of Experimental Medicine. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team suggests that drugs should be developed to strengthen the blood vessels' protective function.

12 Feb 2013

WetAlert wireless wetness detector from Fresenius Medical Care

Fresenius Medical Care, the world's largest provider of dialysis products and services, announced today its introduction of the WetAlert wireless wetness detector, designed to detect venous needle displacement and prevent blood loss for dialysis patients at home.

11 Feb 2013

Frequent hemodialysis can cause vascular complications in patients

Compared with standard dialysis, frequent dialysis can cause complications related to repeated access to the blood, requiring patients to undergo more repair procedures to the site through which blood is removed and returned, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

10 Feb 2013

Positive results from NCI-sponsored bevacizumab trial on cervical cancer

Patients with advanced, recurrent, or persistent cervical cancer that was not curable with standard treatment who received the drug bevacizumab (Avastin) lived 3.7 months longer than patients who did not receive the drug, according to an interim analysis of a large, randomized clinical trial.

10 Feb 2013

Marijuana may double stroke risk in young adults

Marijuana, the most widely used illicit drug, may double stroke risk in young adults, according to research presented at the American Stroke Association's International Stroke Conference 2013.

9 Feb 2013

Intravitreal ranibizumab shows little benefit after hemorrhage

Ranibizumab given intravitreally offers no clear benefit in the treatment of vitreous hemorrhage due to proliferative diabetic retinopathy, a randomized clinical trial indicates.

8 Feb 2013

eGFR ‘powerful’ operative risk gauge

Patients’ estimated glomerular filtration rate is highly predictive of their risk for dying after surgery, shows a systematic review and meta-analysis.

8 Feb 2013

Eletrocardiographic mapping nearing clinical utility

Electocardiographic mapping may offer a noninvasive and accurate alternative to a standard electrophysiologic study, say researchers.

7 Feb 2013

FDA approves Cardiva Medical's VASCADE Vascular Closure System

Cardiva Medical, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Premarket Approval (PMA) for the VASCADE Vascular Closure System (VCS).

6 Feb 2013

Ramipril puts spring in step of patients with intermittent claudication

Six months of treatment with the angiotensin-converting enzyme inhibitor ramipril produces notable improvements in the walking ability of patients with peripheral artery disease and intermittent claudication, shows a large randomized trial.

6 Feb 2013

Patients undergoing major vascular surgery procedures are at increased risk of stroke

Patients undergoing major vascular surgery procedures are at increased risk of stroke, leading to a high mortality rate and prolonged hospitalization, according to a study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

6 Feb 2013

Ramipril may improve pain-free walking among patients with PAD and intermittent claudication

Among patients with peripheral artery disease and intermittent claudication (pain in the calf that comes and goes, typically felt while walking), 24 weeks of treatment with the angiotensin-converting enzyme (ACE) inhibitor ramipril was associated with improvement in pain-free and maximum walking times and the physical health aspect of quality of life, according to a study appearing in the February 6 issue of JAMA.

6 Feb 2013

Acceleron commences dalantercept phase 2 study in metastatic renal cell carcinoma

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, announced the initiation of a phase 2 study of dalantercept, a novel angiogenesis inhibitor that targets the activin receptor-like kinase 1 (ALK1) pathway.

5 Feb 2013

High intensity interval training more suitable to achieve sustainable changes in exercise behaviour

With many of us struggling to get enough exercise, sport and exercise scientists at Liverpool John Moores University (LJMU) and the University of Birmingham, under the lead of Professor Anton Wagenmakers, have been working on a time-saving solution.

3 Feb 2013

SIR, Society for Vascular Surgery partner on IVC filter study

The Society of Interventional Radiology and Society for Vascular Surgery jointly will launch PRESERVE-the first large-scale, multispecialty prospective study to evaluate the use of inferior vena cava (IVC) filters and related follow-up treatment.

2 Feb 2013

Cedars-Sinai healthcare professionals to mark National Wear Red Day

Hundreds of healthcare professionals at the Cedars-Sinai Heart Institute will wear red on Friday, Feb. 1, to mark National Wear Red Day. A few hours later, the new Cedars-Sinai Advanced Health Sciences Pavilion will be lit with a projection of the red dress symbol that represents a public education program to boost women's awareness of heart disease.

1 Feb 2013

Cerebrolysin: a promising new treatment for dementia

Dementia patients may benefit from a promising new treatment called Cerebrolysin, according to the results of a systematic review published in The Cochrane Library. The authors brought together the most up-to-date evidence on Cerebrolysin as a treatment for vascular dementia.

31 Jan 2013

Left ventricular assist device improves quality of life in two brothers with Becker's Muscular Dystrophy

Tyler Wertz, 18, and his 16-year old brother Austin Tucker, fight, tease, love and support each other like most brothers do. Unlike most brothers, however, they share the same uncertain future—both have heart assist devices keeping them alive while they struggle with a debilitating disease. As young boys, Tyler and Austin were diagnosed with Becker's Muscular Dystrophy, a disease that slowly weakens the arms and legs and damages the heart.

31 Jan 2013

STS presents Earl Bakken Scientific Achievement Award to Stanford University professor

The Society of Thoracic Surgeons presented the Earl Bakken Scientific Achievement Award to D. Craig Miller, MD on Tuesday morning during the General Session at the STS 49th Annual Meeting.

31 Jan 2013

Achilles tendon lengthening shows benefits for diabetic foot

Researchers report that the addition of Achilles tendon lengthening to procedures for managing diabetic forefoot and midfoot ulceration seems warranted.

30 Jan 2013