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Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

A new study evaluated neutralizing antibody (nAb) responses against the SARS-CoV-2 Omicron variant induced by booster vaccination with Pfizer-BioNTech’s BNT162b2 messenger ribonucleic acid vaccine.

20 Sep 2022

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational Medicine, researchers in the United States designed a bivalent coronavirus disease 2019 (COVID-19) vaccine on the messenger ribonucleic acid (mRNA) platform.

18 Sep 2022

Concern over two cases of monkeypox-related neurological complications in the U.S.

A new study published in the CDC's Morbidity and Mortality Weekly Report analyzed two people with encephalomyelitis associated with monkeypox disease in Colorado and DC during the current outbreak.

15 Sep 2022

Mechanism of action of different COVID-19 vaccines

In a recent study posted to the bioRxiv* preprint server, researchers at the University of Tuebingen and Imperial College London assessed humoral and cellular immune responses elicited by the recombinant adenoviral vector (rAdVV)- and messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines.

14 Sep 2022

High levels of mucosal antibodies in the airways reduce the risk of omicron infection

High levels of mucosal antibodies in the airways reduce the risk of being infected by omicron, but many do not receive detectable antibodies in the airways despite three doses of the SARS-CoV-2 vaccine.

14 Sep 2022

SARS-CoV-2 RNA and antibody detection in infected mothers’ breast milk

In a recent study published in the Journal of Medical Virology, Italian researchers investigated the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) and antibodies (Abs) in the milk of breastfeeding mothers with SARS-CoV-2 infections.

14 Sep 2022

Customized bivalent mRNA COVID boosters protect against BA.5 Omicron variant

In a recent study posted to the bioRxiv* pre-print server, researchers from Washington University School of Medicine, Moderna, Inc, and the U.S. National Institutes of Health tested two bivalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines based on the messenger ribonucleic acid (mRNA) platform.

14 Sep 2022

Intranasal administration of liposomes displaying SARS-CoV-2 antigen induces mucosal immunity

A new study suggested that an intranasal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine induced mucosal immune responses in mice.

14 Sep 2022

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

In a recent study published in the journal eBioMedicine, researchers in Denmark and Sweden administered a cationic liposome-adjuvanted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit vaccine as a subcutaneous (s.c.) prime-intranasal (i.n.) boost strategy to elicit mucosal immune responses among SARS-CoV-2-infected Syrian hamsters.

14 Sep 2022

Altered T-cell response in hemodialysis patients following third COVID-19 vaccine dose

Scientists define the immune responses against COVID-19 in HD patients who received three mRNA COVID-19 vaccine doses.

13 Sep 2022

Vaccines that induce mucosal immunity against SARS-CoV-2 are needed

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom studied assessed plasma and nasal antibody (Ab) responses induced after a year of coronavirus disease 2019 (COVID-19)-associated hospitalization and the potential boost by subsequent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations in the United Kingdom (UK).

12 Sep 2022

The ongoing 2022 West Nile virus transmission season in Italy

A recent article described the seasonal transmission of the West Nile virus in 2022 and compared the human cases reported in June-July 2022 with the reports in 2018.

12 Sep 2022

A direct side-by-side comparison of all available COVID-19 vaccines

In a recent study posted to the medRxiv* preprint server, researchers assessed immune responses to homologous and heterologous coronavirus disease 2019 (COVID-19) vaccine combinations among Córdoba, Spain residents.

11 Sep 2022

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

Researchers explored probable humoral immune mechanisms related to EBV curtailment, besides neutralization, by a systematic emphasis on antibody fragment crystallizable-functional activities over the course of EBV infections.

9 Sep 2022

All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

Immunoglobulin News and Research

Neutralizing antibody responses, breakthrough SARS-CoV-2 infections, and symptoms after booster BNT162b2 COVID-19 vaccinations

An improved COVID-19 vaccine shows promise against Omicron in experimental models

Concern over two cases of monkeypox-related neurological complications in the U.S.

Mechanism of action of different COVID-19 vaccines

High levels of mucosal antibodies in the airways reduce the risk of omicron infection

SARS-CoV-2 RNA and antibody detection in infected mothers’ breast milk

Customized bivalent mRNA COVID boosters protect against BA.5 Omicron variant

Intranasal administration of liposomes displaying SARS-CoV-2 antigen induces mucosal immunity

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

Altered T-cell response in hemodialysis patients following third COVID-19 vaccine dose

Vaccines that induce mucosal immunity against SARS-CoV-2 are needed

The ongoing 2022 West Nile virus transmission season in Italy

A direct side-by-side comparison of all available COVID-19 vaccines

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

All SARS-CoV-2 variants neutralized by a potent new antibody

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

Biosynthetic proteins show promise as SARS-CoV-2 antivirals targeting spike protein

How does previous SARS-CoV-2 infection impact the B cell receptor repertoire in response to vaccination?

How does SARS-CoV-2 infection and vaccination impact human immune memory?

How does SARS-CoV-2 infection impact fertility in men?

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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