Immune Response News and Research

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Research may provide better tools for designing personalized protocols for cancer patients

Diversity – at least among cancer cells – is not a good thing. Now, research from the Weizmann Institute of Science shows that in melanoma, tumors with cells that have differentiated into more diverse subtypes are less likely to be affected by the immune system, thus reducing the chance that immunotherapy will be effective.

17 Sep 2019

No more tears: immunization without needles

A new study published in the Journal of Investigative Dermatology reports a novel skin vaccine patch which could help effective and safe immunization by disrupting the permeability of the skin, providing a convenient and non-invasive alternative to immunization shots. This innovative technique now needs to be tested in humans.

17 Sep 2019

New biomarkers help predict response to treatment in common brain tumor

Many scientists have noted that there is a link between inflammation or the immune response, and patient survival. One such possible relationship is the association of blood markers and the prognosis in the brain tumor called medulloblastoma.

16 Sep 2019

Uncovering new T cell regulatory processes could help treat autoimmune disease

One of the important cells involved in the immune response is the T follicular helper (Tfh) cell. These are important in the normal process of antibody production following immunization, for instance. However, they are also abnormally increased in number in patients with autoimmune disease, such as systemic lupus erythematosus.

16 Sep 2019

Researchers eliminate need for anti-rejection drugs in mice with transplanted glial cells

In experiments in mice, Johns Hopkins Medicine researchers say they have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs.

16 Sep 2019

'Narrow escape problem' determines the way immune cells pick friends from foes

The way immune cells pick friends from foes can be described by a classic maths puzzle known as the "narrow escape problem".

16 Sep 2019

Study shows how the interplay of two cytokines affects development of Tfh cells

The body's immune response fights against infectious disease, and it safeguards against future infections through vaccination.

15 Sep 2019

B-cell subtypes play essential role in immune response to melanoma

When it comes to further developing modern immunotherapies, cancer research has so far concentrated on T-lymphocytes.

13 Sep 2019

Editing away cancer and HIV in China: win or lose?

Scientists in China recently edited out the CCR5 gene from a patient with HIV's stem cells, but the research has sparked ethical debate.

13 Sep 2019

Scientists design new model for predicting what might make an effective cancer vaccine

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have designed and validated a model for predicting what might make an effective cancer vaccine against a patient's tumor.

13 Sep 2019

Humans have very individualized inflammatory responses to high-fat meal

People have very individualized inflammatory responses to eating a high-fat meal.

12 Sep 2019

Scientists attempt to cure HIV using CRISPR, with varying results

Scientists have used the gene-editing technology CRISPR in an attempt to cure a person infected with HIV, with some success.

12 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

Raising Awareness of Coeliac Disease with Coeliac UK

An interview with Norma McGough from Coeliac UK, debunking some of the common myths surrounding celiac disease and helping to raise awareness of the condition

12 Sep 2019

Scientists identify molecule that plays key role in determining fate of cells under stress

St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum.

12 Sep 2019

Developing next generation treatment to counteract opioid addiction

There are many moments in the human experience when tragedy elicits not only compassion, but inspiration. When Mike Zhang heard the story of a mother whose son died of an opioid overdose just one month after the teenager's introduction to the drug at a party, the Virginia Tech researcher wanted to help.

11 Sep 2019

Research shows link between genetic mutation and flu-related heart complications

People with severe flu sometimes develop life-threatening heart problems, even when their hearts have been previously healthy, but the reason for that has been poorly understood.

10 Sep 2019

Microbiome loss from antibiotic use affects response to flu vaccine

Every living person has trillions of microbes living in their digestive tract, and more than 400 species of bacteria in the gut, more than the number of cells in the body. The normal gut flora is important to maintain eubiosis, the microbial balance in the body.

9 Sep 2019

Fat-filled immune cells found in victims of vaping illness

The frightening outbreak of mysterious respiratory illness linked to the use of e-cigarettes, or vaping, have shaken the medical community.

9 Sep 2019

Oral antibiotics that kill gut microorganisms can alter immune response to flu vaccines

The normal human gut microbiome is a flourishing community of microorganisms, some of which can affect the human immune system. In a new paper published this week in Cell, researchers found that oral antibiotics, which can kill gut microorganisms, can alter the human immune response to seasonal influenza vaccination.

8 Sep 2019