Vascular News and Research

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Arginase, IDO could hold clues to help 79 million Americans with prediabetes

Two enzymes that are elevated in prediabetes could hold clues to helping the 79 million Americans with the condition avoid serious vascular complications and maybe even identify those most at risk for full-blown diabetes, researchers say.

13 Dec 2012

Exoskeleton technology: an interview with Larry Jasinski, CEO, ARGO Medical Technologies

Exoskeleton technology is a rapidly emerging medical field using a combination of sensors, motors, computer based control systems and rechargeable batteries in the form of a skeleton that fits onto the legs and hips of an individual – called an Exoskeleton.

12 Dec 2012

Spotlight on acute respiratory distress syndrome in low-risk surgery

Postoperative acute respiratory distress syndrome is rare in patients undergoing low-risk surgery, but still carries a very high mortality rate, a large study shows.

12 Dec 2012

Dementia therapy: an interview with Assoc Prof. Olivier Piguet and Sharon Savage

Dementia is the umbrella term used to describe a number of neurodegenerative brain disorders that cause progressive changes in thinking abilities and behaviour. The kind of deficits experienced by individuals diagnosed with dementia depends on the location and severity of the pathology in the brain.

11 Dec 2012

CYP2J2 implicated in preeclampsia

Study findings suggest that uteroplacental cytochrome P450 subfamily 2J polypeptide 2 overexpression contributes to preeclampsia.

11 Dec 2012

CYP2J2 implicated in preeclampsia

Study findings suggest that uteroplacental cytochrome P450 subfamily 2J polypeptide 2 overexpression contributes to preeclampsia.

10 Dec 2012

Adiponectin level may underpin atherogenic haptoglobin phenotype

Researchers have suggested an active role for adiponectin in the pathophysiology of vascular disease in patients with diabetes, which depends on their haptoglobin phenotype.

7 Dec 2012

Bilirubin can inhibit clogging of arteries and prevent deadly consequences

Each year, about 610,000 Americans suffer their first heart attack, according to the Centers for Disease Control and Prevention. Heart attacks and other symptoms of cardiovascular disease can be caused when blockage occurs in the arteries. In a new study from the University of Missouri, a scientist has discovered a natural defense against arterial blockage: bilirubin.

6 Dec 2012

Targeted therapy as common as chemotherapy at end of life

Targeted therapies are used as often as chemotherapy at the end of advanced cancer patients' lives, according to study results using US data.

6 Dec 2012

Paper reveals how 'kinase' is distributed across membranes

Using a super-resolution fluorescent microscope, Australian medical scientists are a step closer to understanding why and how human immune cells decide to activate or not, thus enabling or preventing disease taking hold in the body.

5 Dec 2012

New method promises to boost stem cell production in laboratory

A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.

5 Dec 2012

METACARDIS project to develop and implement personalized treatments for patients with CMDs

Thanks to the support of the European Commission, fourteen partners in six European countries will work together over a five-year period to translate the results obtained with novel CMD diagnosis and treatment methods and pave the way for personalised medicine in CMDs. Researchers and clinicians from the Institute of Cardiometabolism and Nutrition (ICAN) will also be involved in the METACARDIS project.

5 Dec 2012

Combining 5-fluorouracil and IL-1 beta inhibitor can improve effectiveness of chemotherapy

These results reveal how the immune system can then limit the effectiveness of some cancer chemotherapies. The researchers now intend to block the molecules responsible for negative immune system activation to increase the efficiency of chemotherapy. A clinical trial to test this hypothesis should begin very soon.

5 Dec 2012

Adiponectin level may underpin atherogenic haptoglobin phenotype

Researchers have suggested an active role for adiponectin in the pathophysiology of vascular disease in patients with diabetes, that depends on their haptoglobin phenotype.

4 Dec 2012

Excess vitamin A intake has calcification repercussions

Excess dietary vitamin A intake is significantly associated with increased heart valve calcification, show results from an animal study.

4 Dec 2012

Chronic periodontitis present more often in men with erectile dysfunction

Men in their thirties who had inflamed gums caused by severe periodontal disease were three times more likely to suffer from erection problems, according to a study published in the Journal of Sexual Medicine.

4 Dec 2012

Innovative stem cell technique for heart tissue revealed

Researchers have found that stem cell cultures infused with growth factors could be used to repair damaged heart tissue without the threat of patient rejection.

3 Dec 2012

Studies demonstrate effectiveness of Nonin's EQUANOX Advance Model 7600 Oximetry System

Nonin Medical, Inc. announced today the publication of two separate studies that demonstrate the clinical efficacy of the company's EQUANOX Model 7600 Cerebral and Somatic Oximetry System in adult and pediatric patients.

30 Nov 2012

Topical simvastatin may be answer to nonhealing diabetic wounds

Topical simvastatin significantly accelerates wound healing in mice and may be a good treatment option for diabetic patients with nonhealing wounds, say researchers.

30 Nov 2012

Yale and Mainz University Medical Center to extend collaboration

The University Medical Center at Johannes Gutenberg University Mainz, Germany and the renowned School of Medicine at Yale University, USA have agreed upon a future collaboration. This strategic partnership promises to provide an innovative stimulus for the Research Unit Translational Neurosciences at the Mainz University Medical Center. The resulting regular exchange will benefit both basic research and the training of young researchers.

29 Nov 2012