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Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

Incidence of post-surgical complications before and during COVID-19 pandemic

Scientists compare post-surgical complications before and during the COVID-19 pandemic.

6 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

Aldosterone levels undetectably low in hospitalized COVID-19 patients

A new study reports finds very low aldosterone levels in a subset of COVID-19 patients.

6 Mar 2022

$20 million scientific research initiative focuses on disparities in maternal-infant heart health

Poor heart health, especially among women of color, puts both mothers-to-be and their infants at risk, with heart disease causing more than one in four pregnancy-related deaths (26.5%) in the U.S., according to the American Heart Association Heart Disease and Stroke Statistics 2022 Update.

6 Mar 2022

Study identifies unique features of MIS-C and how the syndrome gets started in children

A new study by physicians at Columbia University Vagelos College of Physicians and Surgeons has identified unique features of MIS-C, a rare but potentially deadly complication of COVID in children, that suggest how the syndrome gets started.

4 Mar 2022

Practical guidance to prevent central line-associated bloodstream infections in NICU patients

Central line-associated bloodstream infections (CLABSIs) are among the most frequent invasive infections among infants in the NICU and contribute to substantial morbidity and mortality.

4 Mar 2022

NEJM editorial highlights the difficulty of diagnosing heart attacks in postoperative patients

Diagnosing heart attacks after heart surgery remains difficult due to shortcomings of current diagnostic tools when applied to postoperative patients, including the electrocardiogram and blood tests to detect levels of cardiac troponins, according to an editorial in the New England Journal of Medicine (NEJM) written by two UT Southwestern faculty members.

3 Mar 2022

Automation linked to increasing mortality rate among America's working-age adults

The automation of U.S. manufacturing — robots replacing people on factory floors — is fueling rising mortality rate among America's working-age adults, according to a new study by researchers at Yale and the University of Pennsylvania.

3 Mar 2022

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

Convalescent plasma therapy shows no significant impact on COVID-19 recovery and outcomes

Researchers conduct a multi-center study involving hospitalized COVID-19 patients to gather information on the rationale use of convalescent plasma.

3 Mar 2022

Incidence and outcomes of breakthrough SARS-CoV-2 infections in vaccinated chronic liver disease patients

A new study assesses breakthrough SARS-CoV-2 infections in vaccinated CLD patients with cirrhosis as compared to CLD patients without cirrhosis.

3 Mar 2022

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

A new study published on the bioRxiv* preprint server has evaluated bacterial susceptibility during SARS-CoV-2 infection.

3 Mar 2022

WHO experts suggest antiviral drug for patients with non-severe covid-19 at highest risk of hospitalization

The antiviral drug molnupiravir is conditionally recommended for patients with non-severe covid-19 who are at highest risk of hospitalization, says a WHO Guideline Development Group of international experts in The BMJ today.

3 Mar 2022

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

In a new study, researchers presented the Multiscale potential of heat-diffusion for affinity-based trajectory embedding approach that identified multimodal signatures of SARS-CoV-2shut.

3 Mar 2022

A model for predicting the evolution of the Omicron wave

Scientists forecast the temporal evolution of the Omicron wave according to a susceptible-infectious-recovered/removed epidemic compartment model.

3 Mar 2022

UH researcher receives $2 million to develop drugs for traditionally undruggable targets in cancer

With a $2 million recruitment grant from the Cancer Prevention and Research Institute of Texas, a University of Houston researcher is setting up a lab to develop drugs that will work on traditionally undruggable targets in cancer.

2 Mar 2022

Drug overdose death rates among Black Americans surpass that of whites for first time in 20 years

In 2020, the first year of the COVID-19 pandemic, the rate of drug overdose deaths among Black Americans surpassed that of whites for the first time since 1999 - a sharp reversal of the situation a decade earlier, when rates were twice as high for whites as for Blacks, new UCLA research shows.

2 Mar 2022

Using Hla-A*32 allele as a prognostic indicator of COVID-19 severity

In a new study, researchers evaluated the association between human leukocyte antigens alleles and the severity of COVID-19.

2 Mar 2022

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Researchers evaluated the synergistic activity of drugs acting against non-structural protein 1 of SARS-CoV-2 to decrease the viral infectivity.

2 Mar 2022

Mortality News and Research

Combating COVID cytokine storm with targeted nucleic acid therapies

Incidence of post-surgical complications before and during COVID-19 pandemic

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Aldosterone levels undetectably low in hospitalized COVID-19 patients

$20 million scientific research initiative focuses on disparities in maternal-infant heart health

Study identifies unique features of MIS-C and how the syndrome gets started in children

Practical guidance to prevent central line-associated bloodstream infections in NICU patients

NEJM editorial highlights the difficulty of diagnosing heart attacks in postoperative patients

Automation linked to increasing mortality rate among America's working-age adults

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Convalescent plasma therapy shows no significant impact on COVID-19 recovery and outcomes

Incidence and outcomes of breakthrough SARS-CoV-2 infections in vaccinated chronic liver disease patients

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

WHO experts suggest antiviral drug for patients with non-severe covid-19 at highest risk of hospitalization

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

A model for predicting the evolution of the Omicron wave

UH researcher receives $2 million to develop drugs for traditionally undruggable targets in cancer

Drug overdose death rates among Black Americans surpass that of whites for first time in 20 years

Using Hla-A*32 allele as a prognostic indicator of COVID-19 severity

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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