Immune Response News and Research

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Researchers discuss how time of day affects the severity of illness

In a review published May 17 in the journal Trends in Immunology, researchers discuss how time of day affects the severity of afflictions ranging from allergies to heart attacks.

21 May 2019

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues.

21 May 2019

Circadian rhythm influences immune responses across a range of diseases

Researchers in Switzerland have conducted a review of studies looking at how circadian rhythm affects the immune response and severity of illnesses ranging from heart attack to allergy.

20 May 2019

Study explains why several clinical trials of treatments for sepsis have been failed

Much like cancer, sepsis isn't simply one condition but rather many conditions that could benefit from different treatments, according to the results of a University of Pittsburgh School of Medicine study involving more than 60,000 patients.

20 May 2019

University of Virginia chemist identifies potential addiction-free pain reliever

An estimated 1.7 million Americans suffer from substance abuse disorders related to opioid use for pain relief, according to the National Institute on Drug Abuse.

17 May 2019

Researchers inhibit galectin-3 protein that plays a major role Alzheimer’s disease

In recent years, it has become increasingly clear to researchers that the protein galectin-3 is involved in inflammatory diseases in the brain.

15 May 2019

Immune system discovery could inform the development of new stem cell therapies

A discovery of how stem cells are protected from viruses could inform the development of therapies for use in medicine, research suggests.

15 May 2019

Low humidity could be flu virus' best friend

Yale researchers have pinpointed a key reason why people are more likely to get sick and even die from flu during winter months: low humidity.

14 May 2019

Researchers discover biochemical agent responsible for blood pressure drop in sepsis

A study conducted by an international group of researchers has overturned the understanding of life-threatening inflammatory diseases such as sepsis, pointing to a biochemical agent that may be involved in the rapid decline in blood pressure that occurs in the advanced stage of sepsis and usually causes the patient's death. This discovery could pave the way for novel therapeutic approaches.

14 May 2019

Autophagy of dendritic cells supports T-cell anticancer activity

Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell anticancer activity.

13 May 2019

Scientists investigate function of AAPP in mosquito blood feeding

Biting insects use a range of tools when sucking blood from hosts to maximize their chances of a good meal.

13 May 2019

UT Southwestern study suggests why UTIs have high recurrence rate in postmenopausal women

A UT Southwestern study suggests why urinary tract infections have such a high recurrence rate in postmenopausal women - several species of bacteria can invade the bladder walls.

12 May 2019

Slow-release HIV vaccine shows promise in preclinical trials

A new slow-release vaccine has been shown to boost the immune system’s response to the HIV virus. The vaccine is given in small doses over a period of days, compared to one large dose.

10 May 2019

Researchers design promising cell-based regenerative therapy approach for periodontitis

Researchers have designed a safer, faster and cheaper cell-based regenerative therapy approach for the treatment of one of the most common human dental diseases, namely periodontitis.

10 May 2019

Researchers create ‘mini-guts’ to explore how gut epithelium respond to gluten in celiac patients

In pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Center at Massachusetts General Hospital have validated the use of intestinal organoids.

8 May 2019

Long-standing immunosuppressive drug reduces Zika birth defects in mice

In experiments with pregnant mice infected with the Zika virus, Johns Hopkins Medicine researchers report they have successfully used a long-standing immunosuppressive drug to diminish the rate of fetal deaths and birth defects in the mice's offspring.

From Johns Hopkins Medicine 7 May 2019

Research aims to keep astronauts healthy in space

Falling ill while traveling is an unfortunate yet common occurrence. Even a minor bug can ruin an entire trip. But for astronauts, getting sick on a long space voyage would have far more serious consequences than a little spoiled fun.

7 May 2019

Scientists discover biological barrier that keeps cancer at bay

Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function.

6 May 2019

Experts to present tumor DNA, breast and jaw reconstruction studies at PSRC annual meeting

The Plastic Surgery Research Council focuses on awareness surrounding compelling research relating to the field of plastic surgery.

3 May 2019

$30 million federal grant to accelerate chase for universal influenza vaccine

Cincinnati Children's Hospital Medical Center will use a $30 million federal grant--the second-largest the center has ever received--to accelerate the chase for one of medicine's most elusive goals: a universal influenza vaccine.

2 May 2019