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Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

Study on Omicron related mortality in cancer patients during recent COVID wave

A recent pre-proof study published in the journal Cancer Cell assessed the CFR of cancer patients during the third wave of the coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 Omicron variant.

23 Feb 2022

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

A new drug, administered in combination with standard androgen-deprivation therapy and docetaxel chemotherapy, increased survival in patients with metastatic hormone-sensitive prostate cancer, according to a trial published in The New England Journal of Medicine.

23 Feb 2022

White blood cell count as a prognostic indicator of COVID-19

Based on a new study, researchers concluded WBC count variations worsen clinical outcomes such as severity, mortality, and hospital discharge rates leading to a poorer prognosis in COVID-19 patients.

23 Feb 2022

Outcomes of phase 3 clinical trial of CVO PLUS CURATIF capsules for COVID-19 treatment

A phase 3 randomized clinical trial has recently been conducted to investigate the efficacy of a capsule formulation in treating mild-to-moderate COVID-19 patients.

23 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

More evidence vaccines prevent ICU admission and mortality from SARS-CoV-2

In a recent study posted to the medRxiv* preprint server, researchers estimated the comparative virulence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) between the vaccinated and unvaccinated subjects hospitalized with coronavirus disease 2019 (COVID-19) in Canada.

23 Feb 2022

SARS-CoV 2 Omicron prevalent in vaccine breakthrough cases in Bahia, Brazil

In a recent study posted to the medRxiv* pre-print server, researchers performed genomic monitoring to estimate the magnitude and range of the different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in SARS-CoV-2 reinfection cases among fully vaccinated individuals in Salvador, Bahia, Brazil.

23 Feb 2022

Low risk of second allergic reaction after SARS-CoV-2 vaccination

In a recent investigation posted to the journal JAMA Internal Medicine,* researchers estimate the risk of a repeated allergic reaction to the second severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger ribonucleic acid (mRNA) vaccine dose in those with a history of allergic responses following the first dose by conducting a systematic review and meta-analysis.

22 Feb 2022

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

Scientists from Israel have recently estimated the levels of circulating microRNAs (miRNAs) in hospitalized coronavirus disease 2019 (COVID-19) patients with the aim of identifying prognostic biomarkers for disease severity. They have identified miR-155, an important regulatory molecule in the immune system, as a potential biomarker to predict COVID-19 severity and mortality.

22 Feb 2022

Labor neuraxial analgesia associated with reduced risk of severe maternal morbidity

In a study of vaginal births in New York State hospitals, labor neuraxial analgesia – having an epidural or combined spinal and epidural - was associated with a decreased risk of severe maternal morbidity.

22 Feb 2022

REGEN-COV antibody combination to prevent COVID-19 severity

A new study assessed the effectiveness of REGEN-COV, a combination of casirivimab and imdevimab monoclonal antibodies, in the prevention of COVID-19 disease severity.

22 Feb 2022

Studies continue to prove ivermectin for COVID-19 treatment ineffectual

Researchers from hospitals around Malaysia have been looking into the efficacy of the controversial drug ivermectin as a possible COVID-19 treatment.

22 Feb 2022

Lung microbiome alterations and secondary-infections in lethal COVID-19

Researchers examined how an interplay of host and microbial factors weakened immunity leading to secondary infections in COVID-19-infected individuals.

22 Feb 2022

Mouse-adapted virus model to study persistent COVID induced lung disease

Researchers develop a mouse model to identify early biomarkers and test countermeasures needed to detect and prevent PASC.

21 Feb 2022

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

In a recent study published in the journal PLoS ONE, researchers evaluated the temporal spread and geographic distribution of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) genomic variants.

21 Feb 2022

Study reports potently neutralizing mucosal IgA in saliva of BNT162b2 vaccine recipients

researchers determine the strong neutralizing mucosal component emanating from intramuscular administration of an mRNA vaccine.

21 Feb 2022

COVID-19 during pregnancy linked to maternal mortality or morbidity from obstetric complications

Pregnant and postpartum individuals infected with SARS-CoV-2 during pregnancy have an increased risk of maternal mortality or morbidity from obstetric complications, according to a recent study published in JAMA.

21 Feb 2022

The 'Ross procedure' may be a more favorable option for aortic valve replacement in younger adults

The "Ross procedure" may be a more favorable option for aortic valve replacement among patients under 50 years old than more standard mechanical or biological replacements, according to a new study from The Mount Sinai Hospital in New York City.

21 Feb 2022

Pathogens in pneumonia-associated respiratory samples from Wuhan prior to SARS-CoV-2 emergence

An interesting paper in PLoS Pathogens describes the broad situation with respect to respiratory pathogens that cause acute respiratory infection (ARI) and pneumonia in the city.

21 Feb 2022

Mortality News and Research

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Study on Omicron related mortality in cancer patients during recent COVID wave

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

White blood cell count as a prognostic indicator of COVID-19

Outcomes of phase 3 clinical trial of CVO PLUS CURATIF capsules for COVID-19 treatment

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

More evidence vaccines prevent ICU admission and mortality from SARS-CoV-2

SARS-CoV 2 Omicron prevalent in vaccine breakthrough cases in Bahia, Brazil

Low risk of second allergic reaction after SARS-CoV-2 vaccination

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

Labor neuraxial analgesia associated with reduced risk of severe maternal morbidity

REGEN-COV antibody combination to prevent COVID-19 severity

Studies continue to prove ivermectin for COVID-19 treatment ineffectual

Lung microbiome alterations and secondary-infections in lethal COVID-19

Mouse-adapted virus model to study persistent COVID induced lung disease

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

Study reports potently neutralizing mucosal IgA in saliva of BNT162b2 vaccine recipients

COVID-19 during pregnancy linked to maternal mortality or morbidity from obstetric complications

The 'Ross procedure' may be a more favorable option for aortic valve replacement in younger adults

Pathogens in pneumonia-associated respiratory samples from Wuhan prior to SARS-CoV-2 emergence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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