Blood Cancer News and Research

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Study highlights pernicious effect of obesity on blood-making stem cells

New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells).

27 Dec 2017

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

In the first comprehensive analysis of clinical trial enrollment among older adults with blood cancers, researchers from the U.S. Food and Drug Administration found significant gaps in participation among those aged 75 and older when considered against the incidence of these malignancies in this age group, according to research being presented today during the 59th American Society of Hematology Annual Meeting and Exposition in Atlanta.

12 Dec 2017

Scientists develop software that predicts leukemia-specific immune targets

University of North Carolina Lineberger Comprehensive Cancer Center scientists have developed a software program that can accurately predict which tumor-specific markers will show up on the surface of leukemia cells in patients who have received stem cell transplants.

11 Dec 2017

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Among younger patients newly diagnosed with chronic lymphocytic leukemia (CLL), treatment with a combination of chemotherapy and a molecularly targeted drug significantly improves response over what is typically seen with chemotherapy alone, according to an investigator-initiated multi-center phase II clinical trial.

11 Dec 2017

Clinical study uses genetic testing to match AML patients with new therapies

A clinical trial using genetic testing to match acute myeloid leukemia (AML) patients with new therapies is now open at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

6 Dec 2017

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Multiple myeloma is the second most common blood cancer in the United States. Thirty to 50 percent of multiple myeloma patients have extra copies of the gene that encodes the enzyme ADAR1.

6 Dec 2017

Study finds unexpected new drug target for acute myeloid leukemia

A study has found an unexpected new drug target for acute myeloid leukemia (AML) that could open new avenues to develop effective treatments against this potentially lethal disease.

27 Nov 2017

Research shows how HLF gene affects blood cell development

A research group at Lund University in Sweden has found that when the HLF (hepatic leukemia factor) gene -which is expressed in immature blood cells - does not shut down on time, we are unable to develop a functional long-term immune system. This could be a very early stage of leukemia.

22 Nov 2017

UNC Lineberger professor receives The Leukemia & Lymphoma Society grant for immunotherapy research

UNC Lineberger Comprehensive Cancer Center researcher Barbara Savoldo, MD, PhD, was awarded a $600,000, three-year grant from The Leukemia & Lymphoma Society to support research into an immunotherapy treatment being developed with a "safety switch" to safeguard against potential side effects of the treatment.

21 Nov 2017

New technique holds promise to screen cancer cells for drug susceptibility

Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. This can lead to months of treatment with a drug that isn't working.

20 Nov 2017

Breakthrough research brings new procedure closer to helping patients with blood cancer

A new procedure that can prevent the potentially lethal side effects of stem cell transplants is a step closer to helping more patients with blood cancers after a breakthrough in understanding of the key mechanism that makes it work.

17 Nov 2017

California cracks down on weed killer as lawsuits abound

Jack McCall was a fixture at the local farmers market, where he sold avocados and other fruits he grew on his 20-acre ranch in Cambria, on California's Central Coast.

8 Nov 2017

FDA grants approval to first treatment for rare blood cancer

The U.S. Food and Drug Administration today expanded the approval of Zelboraf (vemurafenib) to include the treatment of certain adult patients with Erdheim-Chester Disease (ECD), a rare cancer of the blood.

7 Nov 2017

FDA approves new drug Zelboraf for Erdheim-Chester disease

The United States Food and Drugs Administration (FDA) has approved Zelboraf (vemurafenib), a drug for the treatment of adults with a are type of blood cancer called Erdheim-Chester Disease or ECD.

6 Nov 2017

New CAR-T cell therapy offers effective option for certain blood cancer patients

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis is one of the first centers nationwide to offer a new immunotherapy that targets certain blood cancers.

19 Oct 2017

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element can be a potent force against cancer.

17 Oct 2017

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Hui Feng, MD, PhD, assistant professor of pharmacology and medicine at Boston University School of Medicine, is the recipient of a four-year, $792,000 grant from the American Cancer Society to study why T-cell acute lymphoblastic leukemia (T-ALL) is so aggressive and resistant to treatment.

10 Oct 2017

Blood Cancer News and Research

Study highlights pernicious effect of obesity on blood-making stem cells

FDA researchers find underrepresentation of adults aged 75 years and older in blood cancer clinical trials

Scientists develop software that predicts leukemia-specific immune targets

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Clinical study uses genetic testing to match AML patients with new therapies

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Study finds unexpected new drug target for acute myeloid leukemia

Research shows how HLF gene affects blood cell development

UNC Lineberger professor receives The Leukemia & Lymphoma Society grant for immunotherapy research

New technique holds promise to screen cancer cells for drug susceptibility

Breakthrough research brings new procedure closer to helping patients with blood cancer

California cracks down on weed killer as lawsuits abound

FDA grants approval to first treatment for rare blood cancer

FDA approves new drug Zelboraf for Erdheim-Chester disease

New CAR-T cell therapy offers effective option for certain blood cancer patients

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Researchers pinpoint genetic drivers of diffuse large B cell lymphoma

New research uncovers how blood cancer 'steals' parts of bone marrow cells to thrive

Trial identifies genetic fault that affects treatment response in leukemia patients

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