Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Belzutifan significantly reduced the risk of progression of clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, in patients previously treated with immune checkpoint inhibitors and anti-angiogenic therapies compared with everolimus in a phase 3 clinical trial.

24 Oct 2023

Utilizing Biomarkers in Cancer Prevention, Diagnosis, and Treatment

In this interview, Grace Liu from Sino Biological discusses the crucial role of biomarkers in cancer prevention and diagnosis and how they can help guide treatment decisions.

From Sino Biological Inc. 24 Oct 2023

Lactobacillus iners in tumors: Driving chemoradiation resistance via lactate-induced metabolic rewiring

Investigating tumor and gut microbiome traits that impact chemoradiation therapy in patients with cervical cancer.

24 Oct 2023

Chemotherapy plus immunotherapy improves survival in patients with metastatic urothelial cancer

A clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improved survival in patients with an advanced type of bladder cancer.

22 Oct 2023

Dual-action drug produces shows promising results in neuroendocrine tumor trial

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.

22 Oct 2023

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

A secondary analysis from the SWOG S0931 EVEREST trial has found that in the subgroup of patients with clear-cell renal cell carcinoma (RCC) who were at very-high risk of recurrence, those who were treated with everolimus after surgery had a statistically significant improvement in recurrence-free survival compared to patients getting placebo after surgery.

22 Oct 2023

Ferroptosis regulation of GLS2 as a potential therapeutic strategy against liver diseases

A new editorial paper was published in Oncotarget's Volume 14 on October 19, 2023, entitled, "GLS2 shapes ferroptosis in hepatocellular carcinoma."

19 Oct 2023

TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

The Cancer Prevention and Research Institute of Texas (CPRIT) recently awarded grants to four researchers from the Texas Tech University Health Sciences Center (TTUHSC).

12 Oct 2023

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

The oral manifestations of CD.

12 Oct 2023

New AI software achieves 100% detection rate for melanoma

Skin cancer detection using artificial intelligence (AI) software has rapidly improved, new research has shown, with the latest software reaching a 100% detection rate for melanoma.

11 Oct 2023

New topical drug shows promise in preventing cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma is the second most common type of skin cancer in the United States, impacting approximately 700,000 people each year.

11 Oct 2023

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer's early stages, when it's easiest to treat.

10 Oct 2023

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Non-melanoma skin cancer (NMSC) is causing a greater number of global deaths than melanoma, the more serious form of skin cancer, a new study presented today at the European Academy of Dermatology and Venerology (EADV) Congress 2023 has found.

10 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Breakthrough research could lead to more effective immunotherapies for bowel cancer

Every year, over 15,500 Australians are diagnosed with bowel cancer, and it is the second leading cause of cancer deaths in the country.

6 Oct 2023

Breakthrough study shows immunotherapy can help prevent bladder cancer recurrence

The Alliance for Clinical Trials in Oncology today announced that the Alliance Data and Safety Monitoring Board (DSMB) determined that the phase III AMBASSADOR (A031501) trial met one of its dual primary endpoints of disease-free survival (DFS) for the adjuvant treatment of patients with localized muscle-invasive urothelial carcinoma (MIUC) and locally advanced urothelial carcinoma.

5 Oct 2023

Newly identified protein markers could signal early development of metastatic lung cancer

Researchers at Mays Cancer Center at The University of Texas Health Science at San Antonio (UT Health San Antonio) have identified protein markers that could signal for early development of metastatic lung cancer, providing possibilities for new treatment.

4 Oct 2023

Stereotactic radiation therapy offers new hope for older adults with inoperable kidney cancer

Older adults diagnosed with kidney tumors that are not suitable for surgery may benefit from targeted, high-dose radiation, a new study from Australian and Dutch researchers suggests.

3 Oct 2023

Larger lymph node threshold helps facilitate better risk stratification and treatment decisions in nasopharyngeal carcinoma

According to the American Journal of Roentgenology (AJR), using a 6-mm threshold, rather than a 5-mm threshold, helps facilitate better risk stratification and treatment decisions in patients with nasopharyngeal carcinoma (NPC).

29 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Carcinoma News and Research

Further Reading

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Utilizing Biomarkers in Cancer Prevention, Diagnosis, and Treatment

Lactobacillus iners in tumors: Driving chemoradiation resistance via lactate-induced metabolic rewiring

Chemotherapy plus immunotherapy improves survival in patients with metastatic urothelial cancer

Dual-action drug produces shows promising results in neuroendocrine tumor trial

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

Ferroptosis regulation of GLS2 as a potential therapeutic strategy against liver diseases

TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

New AI software achieves 100% detection rate for melanoma

New topical drug shows promise in preventing cutaneous squamous cell carcinoma

New blood test could detect ovarian cancer early, improve treatment

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

Breakthrough research could lead to more effective immunotherapies for bowel cancer

Breakthrough study shows immunotherapy can help prevent bladder cancer recurrence

Newly identified protein markers could signal early development of metastatic lung cancer

Stereotactic radiation therapy offers new hope for older adults with inoperable kidney cancer

Larger lymph node threshold helps facilitate better risk stratification and treatment decisions in nasopharyngeal carcinoma

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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