Clinical Trial News and Research

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Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors

New results from a clinical trial co-led by UCLA investigators demonstrate how treating desmoplastic melanoma, a rare and aggressive skin cancer, with immunotherapy before surgery can dramatically shrink or even eliminate tumors, sparing patients from more aggressive surgeries and preserving their quality of life.

29 Jan 2026

Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026

Whereas conventional treatments such as chemotherapy and radiotherapy show their limitations in battling certain advanced cancers, immunotherapy and therapeutic vaccines have opened up a new realm of hope for patients.

29 Jan 2026

Wake-promoting drug improves alertness in early morning shift workers

Many more people work very early morning shifts than overnight ones, and a large proportion struggle with excessive sleepiness from shift work disorder, leading to problems with focus, performance and safety.

29 Jan 2026

Poop pills could help cancer patients respond to immunotherapy while reducing toxic side effects

Fecal microbiota transplants (FMT), can dramatically improve cancer treatment, suggest two groundbreaking studies published in the prestigious Nature Medicine journal.

28 Jan 2026

Eating beef as part of a healthy dietary pattern does not impact risk factors for type 2 diabetes

More than 135 million American adults are either living with or at risk for type 2 diabetes (T2D), elevating the need for more evidence-based dietary guidance to help this growing population achieve optimal health and reduce risks for T2D and its complications.

28 Jan 2026

Nudges to clinicians and patients increase the rate of influenza vaccination

Patients were 28 percent more likely to get a flu shot when they got a text message reminder and their primary care provider already had an order for the shot waiting, new research from the Perelman School of Medicine showed.

28 Jan 2026

Novel laser focal therapy device shows promising results for prostate cancer treatment

Because treatment of the whole prostate can lead to long-term side effects in patients with prostate cancer, interest in minimally invasive, focal treatment options has been growing for certain patients.

28 Jan 2026

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

A newly approved National Cancer Institute-funded clinical trial aims to improve survival for head and neck cancer patients whose disease returns after radiation therapy – a setback that affects up to 40% of patients and is often associated with poor outcomes.

27 Jan 2026

New research initiative aims to develop retinal screening tool for Alzheimer's

The human eye may literally become a window revealing the earliest signals of Alzheimer's disease, thanks to a new federally funded research initiative at Oregon Health & Science University.

27 Jan 2026

HHCM awards $566K to advance psychedelic end-of-life care research

Healing Hearts, Changing Minds (HHCM) today announced the seven awardees of Walking Each Other Home: A Fund to Promote Psychedelic Compassion for End-of-Life Care, a $566,260 philanthropic initiative supporting innovation, compassion, and dignity for people at life's end.

27 Jan 2026

Vortex Biotech opens new state-of-the-art laboratory at Manchester Science Park

Vortex Biotech Holdings Limited has announced the opening of its advanced laboratory facilities at Manchester Science Park.

27 Jan 2026

Game-changing discovery reveals how viruses may trigger ALS development

A large, multidisciplinary team led by researchers from Texas A&M University has made a potentially game-changing discovery about the development of devastating motor neuron diseases like amyotrophic lateral sclerosis (ALS).

27 Jan 2026

Prospera™ featured in landmark interventional study advancing lung transplant care

Natera, Inc., a global leader in cell-free DNA and precision medicine, today announced the publication of a new prospective clinical trial in Transplantation Direct. The study, which was conducted by The Ohio State University Wexner Medical Center (OSU-WMC), was initiated to explore whether donor-derived cell-free DNA (dd-cfDNA) surveillance, and specifically Prospera-guided monitoring, could reduce the number of invasive biopsies for patients following lung transplantation.

From Natera 27 Jan 2026

New 2026 guideline expands access to advanced acute ischemic stroke care

Expanded eligibility for advanced stroke therapies and new recommendations for diagnosing and treating stroke in children and adults are among the major updates in the new 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke from the American Stroke Association, a division of the American Heart Association, published today in the Association's flagship journal Stroke.

26 Jan 2026

New trial tests strategies to protect heart health during prostate cancer therapy

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, has opened a phase 2 clinical trial comparing three different strategies for protecting heart health in prostate cancer patients who receive androgen deprivation therapy (ADT), a potentially lifesaving hormone therapy.

26 Jan 2026

Why exercise is essential for restoring fitness after GLP-1-based weight loss

This randomized controlled trial shows that structured moderate-to-vigorous exercise, alone or combined with liraglutide, improves physical function and cardiorespiratory fitness after diet-induced weight loss in adults with obesity. In contrast, liraglutide alone sustains weight loss but does not significantly improve measured physical fitness outcomes.

26 Jan 2026

AI-designed NLRP3 inhibitor receives FDA clearance for Parkinson disease trials

Insilico Medicine (3696.HK), a clinical-stage drug discovery and development company driven by generative artificial intelligence (AI), today announced that ISM8969, an orally available NLRP3 inhibitor targeting inflammation and neurodegenerative disorders, has recently received investigational new drug (IND) clearance from the U.S. Food and Drug Administration (FDA), intended for the treatment of Parkinson's Disease.

23 Jan 2026

New partnership aims to expand global access to sickle cell gene therapy

Caring Cross, a 501(c)(3) non-profit dedicated to improving access to advanced therapies, and Boston Children's Hospital today announced a collaboration to provide a sustainable, affordable pathway for patients to access stem cell gene therapies for the treatment of Sickle Cell Disease (SCD).

22 Jan 2026

Cancer vaccines enter a new era of personalized immunotherapy

A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when combined with other cancer treatments.

22 Jan 2026

Menopausal hormone therapy linked to greater weight loss with tirzepatide

A new study led by Mayo Clinic found that postmenopausal women receiving menopausal hormone therapy lost 35% more weight while taking tirzepatide, a Food and Drug Administration-approved drug for the treatment of overweight and obesity.

22 Jan 2026

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Clinical Trial News and Research

Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors

Two-pronged therapeutic technology for cancer wins Pfizer Prize for Biomedical Research 2026

Wake-promoting drug improves alertness in early morning shift workers

Poop pills could help cancer patients respond to immunotherapy while reducing toxic side effects

Eating beef as part of a healthy dietary pattern does not impact risk factors for type 2 diabetes

Nudges to clinicians and patients increase the rate of influenza vaccination

Novel laser focal therapy device shows promising results for prostate cancer treatment

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

New research initiative aims to develop retinal screening tool for Alzheimer's

HHCM awards $566K to advance psychedelic end-of-life care research

Vortex Biotech opens new state-of-the-art laboratory at Manchester Science Park

Game-changing discovery reveals how viruses may trigger ALS development

Prospera™ featured in landmark interventional study advancing lung transplant care

New 2026 guideline expands access to advanced acute ischemic stroke care

New trial tests strategies to protect heart health during prostate cancer therapy

Why exercise is essential for restoring fitness after GLP-1-based weight loss

AI-designed NLRP3 inhibitor receives FDA clearance for Parkinson disease trials

New partnership aims to expand global access to sickle cell gene therapy

Cancer vaccines enter a new era of personalized immunotherapy

Menopausal hormone therapy linked to greater weight loss with tirzepatide

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