Serine News and Research

RSS

Supplying nutritional amino acid restores spatial memory in mouse model of Alzheimer's

Scientists at the Laboratoire des Maladies Neurodégénératives and the Neurocentre Magendie have just shown that a metabolic pathway plays a determining role in Alzheimer's disease's memory problems.

3 Mar 2020

Supplementing diet with amino acid delays signs of ALS in animal study

The addition of dietary L-serine, a naturally occurring amino acid necessary for formation of proteins and nerve cells, delayed signs of amyotrophic lateral sclerosis in an animal study.

24 Feb 2020

Scientists develop self-propelling chemical trap to corner and destroy pathogens

Antibiotics are more efficient when they can act on their target directly at the site of infestation, without dilution.

30 Jan 2020

Research reveals key molecular target for colorectal cancer therapy

Serine racemase is a multifunctional enzyme that carries out several different reactions in human cells, including the conversion of L-serine into pyruvate.

29 Jan 2020

Impaired gene expression may influence aging via altered cellular metabolism

Throughout history, humans have been obsessed with finding a way to prevent aging and prolong life. Although the mechanisms have long eluded us, modern science is revealing more and more about the aging process. Now, researchers from Japan have uncovered new information about the genetic processes that may trigger age-related disorders, including low energy production and low cellular growth.

20 Nov 2019

Research shows how bad E. coli gain a foothold over good bacteria in IBD

What if you had to plan your outings based on how your stomach felt that day or where the nearest restroom is located? For many people with inflammatory bowel disease (IBD), their guts have an inordinate effect on their daily quality of life.

5 Nov 2019

Researchers make major breakthrough in cell signalling

Researchers at the University of Liverpool have made a major breakthrough in the field of cell signalling.

4 Nov 2019

Researchers discover metabolic vulnerability in cancer cells with mutated spliceosomes

A research team from the Johns Hopkins Kimmel Cancer Center reports it has discovered a metabolic vulnerability in multiple types of cancer cells that bear a common genetic mutation affecting cellular machines called spliceosomes.

From Johns Hopkins Medicine 3 Oct 2019

Study shows how a toxin produced by algal blooms in saltwater may cause ALS

Can a computer be used to explain why an environmental toxin might lead to neurodegenerative disease? According to Penn State College of Medicine researchers, a computer generated-simulation allowed them to see how a toxin produced by algal blooms in saltwater might cause Amyotrophic Lateral Sclerosis.

17 Sep 2019

LMRI scientists discover cause of debilitating eye disease

Scientists at the Lowy Medical Research Institute have discovered one cause of a progressive, debilitating eye disease called macular telangiectasia type 2 (MacTel).

11 Sep 2019

First genetic cause for a rare eye disease discovered

John A. Moran Eye Center physician-researcher Paul S. Bernstein, MD, PhD, and his patients at the University of Utah played a key role in the recent discovery of the first genetic cause for a rare eye disease.

11 Sep 2019

Study finds specific direct targets for lung cancer treatment

A team of researchers at the Salk Institute has found two therapeutic targets for the deadly type of lung cancer, non-small-cell lung carcinomas (NSCLCs), which accounts for 85 percent of all lung cancer cases. They believe that the breakthrough discovery could pave the way for the development of new treatments for a majority of lung cancer patients.

29 Jul 2019

Unexpected discovery could improve treatment of cancer, other diseases

EU-funded researchers have discovered an important new mechanism by which cells flag and repair damage to their DNA - an unexpected finding that could improve the treatment of diseases such as cancer.

23 Jul 2019

Study sheds light on complex caspase-1-induced cell death mechanisms

Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program.

5 Jul 2019

Targeted treatment offers symptom relief for patients with psychosis

Treatment for individuals who experience psychosis, such as hallucinations and delusions as a result of a psychiatric illness, can be targeted to a specific structural mutation, according to a study published by researchers from McLean Hospital and other institutions in the journal Biological Psychiatry.

3 Jul 2019

UAB scientists identify new target for drug intervention in Alzheimer's disease

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer's disease and other dementias.

26 Jun 2019

Dietary supplement improves neuronal function of a patient with atypical Rett syndrome

A multicentric translational research study carried out by groups of the Bellvitge Biomedical Research Institute, Sant Joan de Déu Hospital, the University of Barcelona, Hospital Clínic, the University of Vic, Sant Pau i la Santa Creu Hospital, the Rare Diseases Networking Biomedical Research Centre and the Commissariat à l'Énergie Atomique, has demonstrated the potential of the amino acid L-serine - administered as a dietary supplement - to improve the neuronal function of a patient with a mutation of glutamate receptors associated with atypical Rett syndrome with severe encephalopathy.

19 Jun 2019

Scientific discovery may lead to a treatment for lupus

A team of scientists has uncovered the structure of a regulatory complex that is involved in the release of cytokines and can be inhibited to treat lupus.

31 May 2019

Researchers find new molecular targets for fighting autoimmunity

BRCA--the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers--interacts with a multipart, molecular complex that is also responsible for regulating the immune system.

30 May 2019

Inhibition of CRMP2 phosphorylation promotes axonal regeneration after optic nerve injury

A new study by Professor Toshio Ohshima of Waseda University has found that the inhibition of phosphorylation of collapsing response mediator protein 2, a microtubule-binding protein, suppresses degeneration of nerve fibers and promotes its regeneration after optic nerve injury.

22 May 2019