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Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

A new review paper published in PLoS Pathogens discusses the new variants and the structural mechanism underlying antibody-mediated neutralization as well as mutational antibody escape.

21 Feb 2022

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

Researchers investigated whether age-dependent changes in lung physiology make the elderly disproportionately susceptible to SARS-CoV-2 infection.

21 Feb 2022

Emergence of new HIV variant underscores importance of monitoring virus mutations

A new study published in the journal Science reported the presence of a subtype-B variant of HIV-1 with remarkably high virulence, circulating in the Netherlands during the past two decades.

20 Feb 2022

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

A new study focuses on understanding the factors associated with the ability of the Omicron variant to infect a wide range of age groups.

20 Feb 2022

Four times as many children hospitalized during Omicron COVID wave compared to Delta

The emergence of the SARS-CoV-2 Delta and Omicron variants caused severe disease and hospitalizations among children and adolescents.

20 Feb 2022

Omicron outbreak in an indoor convention in New York

A recent report published by the CDC, USA, has demonstrated one of the earliest outbreaks of omicron infection in the US.

18 Feb 2022

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines.

18 Feb 2022

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

In a new study, researchers evaluated the efficacy and safety of nirmatrelvir in mild to moderate COVID-19 patients who were at high risk of severe COVID-19 disease.

18 Feb 2022

As covid slogs on, seniors find fortitude waning and malaise growing

Late one night in January, Jonathan Coffino, 78, turned to his wife as they sat in bed. "I don't know how much longer I can do this," he said, glumly.

18 Feb 2022

New insights could help long-term care facilities enhance infection prevention and control measures

Findings from a study published today in the American Journal of Infection Control provide new insights that could help long-term care facilities assess the cleanliness of high-touch surfaces, and thereby enhance infection prevention and control measures designed to prevent serious diarrheal diseases and deaths among their residents.

17 Feb 2022

Dual access veno-arterial approach increases mortality rate for babies in respiratory failure put on ECMO

The current trend of using two cannulas to place most newborns in respiratory failure on life-sustaining ECMO, one in the right internal jugular vein and a second in the right common carotid artery, rather than a single cannula in the right internal jugular, increases mortality rates for these babies, investigators report.

17 Feb 2022

Trial of early antiviral therapy for COVID-19 shows no significant benefit

A new preprint research paper examines the efficacy of using three antivirals in various combinations in early infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Feb 2022

MRI screenings may reduce breast-cancer mortality in women with 3 pathogenic gene variants

Annual MRI screenings starting at ages 30 to 35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes, according to a comparative modeling analysis to be published Feb. 17, 2022, in JAMA Oncology.

17 Feb 2022

Mortality News and Research

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

Emergence of new HIV variant underscores importance of monitoring virus mutations

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

Four times as many children hospitalized during Omicron COVID wave compared to Delta

Omicron outbreak in an indoor convention in New York

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

As covid slogs on, seniors find fortitude waning and malaise growing

New insights could help long-term care facilities enhance infection prevention and control measures

Dual access veno-arterial approach increases mortality rate for babies in respiratory failure put on ECMO

Trial of early antiviral therapy for COVID-19 shows no significant benefit

MRI screenings may reduce breast-cancer mortality in women with 3 pathogenic gene variants

2022 adult immunization schedule released by ACIP

Immune-boosting supplements do not lessen risk of death from COVID-19, review finds

Identifying direct and indirect effects of SARS-CoV-2 pandemic on mortality in the US

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

Reduction in the sex ratio at birth found following the COVID-19 pandemic

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Risk factors for COVID-19 in older adult patients with cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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