Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Scientists boost protein supply to enhance muscle function, reduce nerve-dependent fatigue in mice

Researchers at Vanderbilt University have "engineered" a mouse that can run on a treadmill twice as long as a normal mouse by increasing its supply of acetylcholine, the neurotransmitter essential for muscle contraction.

21 Dec 2010

Response Biomedical strengthens patent protection for RAMP technology

Response Biomedical Corporation today announced that the United States Patent and Trademark Office issued an official Notice of Allowance on one of the Company's patent applications regarding the RAMP® technology. The patent entitled "Comparative Multiple Analyte Immunoassay" is expected to issue in the first quarter of 2011.

20 Dec 2010

Participants in CMS, Premier healthcare alliance HQID VBP project raise quality by 18.3%

With value-based purchasing (VBP) now law under health reform, hospitals participating in the nation's largest hospital VBP demonstration are providing lessons learned that can help others save lives and better craft rules to govern the new program.

20 Dec 2010

Cardio3 BioSciences presents positive C3BS-GQR-1 results in patients with acute myocardial infarction

Cardio3 BioSciences, a leader in the discovery and development of regenerative and protective therapies for the treatment of cardiovascular diseases, today announces positive pre-clinical results from its in-house product candidate C3BS-GQR-1, to treat patients suffering from acute myocardial infarction in order to protect cardiac tissue from damage and direct heart stem cells to mature and restore pump function.

20 Dec 2010

FDA moves to curb Avastin's approval for breast cancer

The Food and Drug administration on Thursday revoked its approval of Roche drug Avastin for the treatment of breast cancer. The agency's action, based on findings that did not confirm that the medicine helped patients with this disease, has drawn criticism from patients and politicians.

20 Dec 2010

$FDA approves Medtronic's Arctic Front Cardiac CryoAblation Catheter system for drug refractory PAF$

FDA approves Medtronic's Arctic Front Cardiac CryoAblation Catheter system for drug refractory PAF

Medtronic, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved its Arctic Front® Cardiac CryoAblation Catheter system, the first and only Cryoballoon in the United States indicated for the treatment of drug refractory paroxysmal atrial fibrillation (PAF). The Cryoballoon treatment involves a minimally-invasive procedure that efficiently creates circumferential lesions around the pulmonary vein, which is the source of erratic electrical signals that cause the irregular heartbeat.

20 Dec 2010

Nanosphere's Verisens cTnI assay measures low levels of troponin I in patients with heart failure

A clinical study released online by the European Journal of Heart Failure, a publication of the European Society of Cardiology, demonstrates the value of using Nanosphere's Verisens cTnI assay to detect very low levels of troponin I in hospitalized patients with heart failure.

20 Dec 2010

AHA recognizes UC Irvine Medical Center's commitment to high-quality cardiac care

The American Heart Association has recognized UC Irvine Healthcare's commitment to the highest standards of care for heart failure patients.

17 Dec 2010

Genentech confirms EMA, FDA updates on Avastin for metastatic breast cancer

Genentech, a member of the Roche Group, confirmed that following the reviews of Avastin® (bevacizumab) in metastatic breast cancer by the European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA), the following regulatory announcements were made by the individual health authorities:

17 Dec 2010

Study suggests blood test may detect persons with CKD

An infrequently used blood test can effectively identify individuals at increased risk of developing complications associated with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

17 Dec 2010

Reuters rates hospitals' cardiovascular program

Loyola University Hospital's mortality rate from heart-bypass surgery is 74 percent lower than the mortality rate at peer hospitals, according to Thomson Reuters Cardiovascular Benchmarks Report.

17 Dec 2010

FDA recommends removal of breast cancer indication from Avastin label

The U.S. Food and Drug Administration announced today that the agency is recommending removing the breast cancer indication from the label for Avastin (bevacizumab) because the drug has not been shown to be safe and effective for that use.

17 Dec 2010

Miracor granted CE-Mark for PICSO Impulse System to improve ACS revascularization following PCI

Miracor Medical Systems GmbH announced today that the company has received CE-mark for the PICSO® (Pressure-controlled Intermittent Coronary Sinus Occlusion) Impulse System, designed to improve acute coronary syndrome (ACS) revascularization following primary percutaneous coronary intervention (PCI).

16 Dec 2010

Study finds occurrence of infection following surgical procedures

Delaying elective surgical procedures after a patient has been admitted to the hospital significantly increases the risk of infectious complications and raises hospital costs, according to the results of a new study in the December issue of the Journal of the American College of Surgeons.

16 Dec 2010

Nation's leading health care systems collaborate to improve quality while reducing costs

Six of the nation's leading health care systems today announced a first-of-its-kind collaboration to improve health care quality while reducing costs.

16 Dec 2010

FDA to review Lantheus' DEFINITY sNDA for use in stress echocardiography

Lantheus Medical Imaging, Inc., a worldwide leader in diagnostic medical imaging, today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the company's supplemental New Drug Application (sNDA) for DEFINITY® (Perflutren Lipid Microsphere) Injectable Suspension for use in stress echocardiography.

14 Dec 2010

U-M's participation in Medicare Physician Group Practice Demonstration Project helps save over $15 million

Medicare patients with a host of physical problems are getting better care at the University of Michigan Health System, and U-M staff have saved more than $15 million on the cost of that care over four years.

13 Dec 2010

Pfizer withdraws Thelin for treatment of PAH, discontinues global clinical studies

Pfizer Inc. announced today that, in the interest of patient safety, it is voluntarily withdrawing Thelin® (sitaxentan) for the treatment of pulmonary arterial hypertension (PAH) in regions where it is approved (the European Union, Canada and Australia). In addition, Pfizer is discontinuing clinical studies of Thelin worldwide.

10 Dec 2010

HeartWare prices public offering of convertible senior notes due 2017

HeartWare International, Inc. announced today the pricing of a public offering of $125 million principal amount of convertible senior notes due 2017 (the "notes") pursuant to an effective shelf registration statement filed with the Securities and Exchange Commission ("SEC") yesterday.

10 Dec 2010

Serodus licenses selective serotonin-4 antagonist for potential heart failure treatment from Roche

Serodus AS today announced that it has entered into a license agreement with Roche for a selective serotonin-4 (5-HT4) antagonist for the potential treatment of heart failure (RO1160367).

10 Dec 2010

Heart Failure News and Research

Further Reading

Scientists boost protein supply to enhance muscle function, reduce nerve-dependent fatigue in mice

Response Biomedical strengthens patent protection for RAMP technology

Participants in CMS, Premier healthcare alliance HQID VBP project raise quality by 18.3%

Cardio3 BioSciences presents positive C3BS-GQR-1 results in patients with acute myocardial infarction

FDA moves to curb Avastin's approval for breast cancer

FDA approves Medtronic's Arctic Front Cardiac CryoAblation Catheter system for drug refractory PAF

Nanosphere's Verisens cTnI assay measures low levels of troponin I in patients with heart failure

AHA recognizes UC Irvine Medical Center's commitment to high-quality cardiac care

Genentech confirms EMA, FDA updates on Avastin for metastatic breast cancer

Study suggests blood test may detect persons with CKD

Reuters rates hospitals' cardiovascular program

FDA recommends removal of breast cancer indication from Avastin label

Miracor granted CE-Mark for PICSO Impulse System to improve ACS revascularization following PCI

Study finds occurrence of infection following surgical procedures

Nation's leading health care systems collaborate to improve quality while reducing costs

FDA to review Lantheus' DEFINITY sNDA for use in stress echocardiography

U-M's participation in Medicare Physician Group Practice Demonstration Project helps save over $15 million

Pfizer withdraws Thelin for treatment of PAH, discontinues global clinical studies

HeartWare prices public offering of convertible senior notes due 2017

Serodus licenses selective serotonin-4 antagonist for potential heart failure treatment from Roche

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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