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myeloMATCH program opens enrollment for acute myeloid leukemia and MDS

Four leading cancer research organizations in the United States and Canada announce the opening of patient enrollment to myeloMATCH, a unique portfolio of clinical trials to test precision medicine treatments for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

23 Oct 2024

Healthy habits in middle age may protect against neurological conditions

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a study published in the October 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Oct 2024

Poor sleep quality linked to increased brain aging in middle age

People in early middle age who have poor sleep quality, including having difficulty falling or staying asleep, have more signs of poor brain health in late middle age, according to a study published in the October 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Oct 2024

Urine RNA analysis shows promise for detecting genitourinary diseases

Early detection is critical when it comes to curing diseases like cancer, but not everyone has easy access to screening tools.

23 Oct 2024

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy - similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis - also may be an effective treatment strategy for heart failure.

23 Oct 2024

NIH launches precision medicine trial to test new treatments for myeloid cancers

The National Institutes of Health (NIH) has launched a proof-of-concept precision medicine clinical trial to test new treatment combinations targeting specific genetic changes in the cancer cells of people with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).

23 Oct 2024

Researchers discover how ovarian tumors cripple immune cells

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack - blocking the energy supply T cells depend on.

23 Oct 2024

WHO faces challenges in delivering aid amid intensifying hostilities in Gaza

On 21 October, 14 patients and 10 caregivers were transferred from Kamal Adwan in North Gaza to Al-Shifa Hospital in Gaza City during a high-risk, WHO-led joint mission, amid intense hostilities and access restrictions.

23 Oct 2024

Maternal antibodies may hinder malaria vaccine effectiveness in infants

Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, which would explain its lower efficacy in infants under five months of age, according to research led by the Barcelona Institute for Global Health (ISGlobal), in collaboration with seven African centers (CISM-Mozambique, IHI-Tanzania, CRUN-Burkina Faso, KHRC-Ghana, NNIMR-Ghana, CERMEL-Gabon, KEMRI-Kenya).

23 Oct 2024

Groundbreaking findings on TET2 pathway open doors for targeted blood cancer treatments

Approximately 30% of individuals with myeloid malignancy diseases have a mutation in a certain gene called tet methylcytosine dioxygenase 2 (TET2).

23 Oct 2024

Study links dehydration to muscle cramps in IRONMAN athletes

As athletes prepare to dive into Hawaiian waters for the first part of the IRONMAN World Championship on Oct. 26, they may want to pay a little extra attention to the water inside their bodies.

23 Oct 2024

Migraines linked to healthy vascular system despite cardiovascular risk factors

The study links cardiovascular health to migraine activity, showing that lower risk scores are associated with higher migraine likelihood, especially in women.

23 Oct 2024

Can you rely on your mammogram to identify heart disease risk?

When people check in for their annual mammogram these days, some may face a surprising question: In addition to reviewing the mammogram for breast cancer, would the patient like the radiologist to examine the images for heart disease risk?

23 Oct 2024

Study connects brain volume variations with genetic risk factors for Parkinson’s disease and ADHD

Unprecedented genome analysis reveals genetic links between brain structure and disorders like Parkinson's and ADHD, paving the way for innovative treatments.

23 Oct 2024

Maternal stress and depression alter infant DNA, with potential lifelong impact

Maternal stress and depression during pregnancy and postpartum are linked to DNA methylation changes in infants, potentially affecting their development and long-term health.

23 Oct 2024

Scurvy may be making a comeback amid economic strain

The scourge of scurvy, which is caused by vitamin C deficiency, may be re-emerging amid the cost of living crisis and the rise in weight loss (bariatric) surgery, suggest doctors in the journal BMJ Case Reports after treating a middle-aged man with the condition.

22 Oct 2024

Study links schizophrenia to increased risk of sudden cardiac death

The lifetime risk of an unexpected and sudden death from a cardiovascular cause in the absence of pre-existing heart disease - known as sudden cardiac death - is more than 4 times higher for people with schizophrenia than it is for the general population, indicates Danish research published online in the journal Heart.

22 Oct 2024

Physical tests offer prognostic insights for lung cancer patients

A study of patients with metastatic lung cancer by researchers based in Brazil and the United States has found that their performance in simple physical tests such as sitting down, standing and walking can help physicians arrive at a prognosis and approach to treatment.

22 Oct 2024

Caloric restriction extends mouse lifespan and health in new genetic study

Study examined the effects of caloric restriction (CR) and intermittent fasting (IF) on the health and lifespan of genetically diverse female mice, revealing that CR extended lifespan more significantly than IF. Genetic factors also played a role in how dietary restriction influenced aging and health.

22 Oct 2024

Elderberry juice boosts fat burning and gut health in overweight adults

A study found that anthocyanin-rich elderberry juice can improve gut microbiota, reduce blood glucose levels, and increase fat oxidation in overweight adults after just one week of consumption.

22 Oct 2024