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Neural stem cells for Parkinson's disease

A University of South Florida neuroscientist reports that the cutting-edge research study of human stem cells in primates with Parkinson's disease is compelling on several fronts , particularly how the transplanted cells did their job of easing disease symptoms.

11 Jul 2007

Genetically engineered herpes simplex virus keeps arteries free-flowing

A genetically engineered herpes simplex virus, primarily known for causing cold sores, may help keep arteries "free-flowing" in the weeks following angioplasty or stent placement for patients, according to research published early in the online edition of PNAS (Proceedings of the National Academy of Sciences of the United States of America).

11 Jul 2007

Kaposi sarcoma tumors arise independently from multiple cells

Kaposi sarcoma is unique among cancers because most tumors grow from a small number of different cells, whereas nearly all other cancers arise from a single cell, according to a study published online July 10 in the Journal of the National Cancer Institute.

11 Jul 2007

Adiponectin serves as energy-conserving signal to the brain

A fat-derived protein known for its effects on the liver and skeletal muscle might also serve as an energy-conserving signal to the brain during periods of starvation, suggests a new study in the July issue of Cell Metabolism, a publication of Cell Press.

11 Jul 2007

Incretin-based therapy offers alternative option for treating type 2 diabetes

A review of previous studies indicates that use of a class of medications known as “incretin-based therapy”, which act via certain pathways that affect glucose metabolism may provide modest effectiveness and favorable weight change outcomes for the treatment of type 2 diabetes and may represent an alternative to other hypoglycemic therapies.

11 Jul 2007

Abiogen licenses RFB4 antibody from Cancer Research Technology

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, today announces it has agreed an exclusive worldwide licence with Abiogen Pharma S.p.A. (Italy).

11 Jul 2007

How immune cells catch pathogens

To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalise and destroy them.

11 Jul 2007

Top brain experts say alcohol does not destroy brain cells

At an international neural stem cell conference in Australia, ninety of the world's top scientists in neural stem cell and brain development research, from 11 different countries were brought together last month by the Queensland Brain Institute (QBI).

11 Jul 2007

Magnetic nano tweezers show how cancer drug works

The annoying bulges of an over-wound telephone cord that shorten its reach and limit a caller's motion help to explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators at St. Jude Children's Research Hospital and Delft University of Technology.

10 Jul 2007

New insights into acute promyelocytic leukemia

Results from two new studies provide key mechanistic insights into the complex molecular events that cause a deadly type of leukemia.

10 Jul 2007

Scientists take exciting approach for attacking cancers

A new study identifies a combination therapy that may sensitize human cancer cells to a promising treatment currently being used in clinical trials.

10 Jul 2007

U.S. trial of new microbicide for HIV prevention to be tested in young women

Nearly half of all people infected with HIV/AIDS are now women, the majority of whom contracted the disease through sexual intercourse with male partners.

10 Jul 2007

Rapid evolution of defense genes in plants may produce hybrid incompatibility

One of the basic tenets of evolution is speciation in which populations of the same species become so genetically and morphologically variable that they can be classified as two different species.

10 Jul 2007

Peregrine licenses worldwide rights to a novel anti-angiogenesis technology

Peregrine Pharmaceuticals, Inc. has announced that it has licensed worldwide exclusive rights to a novel anti-angiogenesis technology from The University of Texas M. D. Anderson Cancer Center.

10 Jul 2007

Researchers discover how microRNAs control protein synthesis

While most RNAs work to create, package, and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression.

10 Jul 2007

Breast cancers to be more aggressive in African-American women

A study of more than 2,200 women at the Kimmel Cancer Center at Jefferson in Philadelphia shows that African American women have more advanced breast cancer at the time of diagnosis than Caucasian women.

10 Jul 2007

ERG gene's activity points to more lethal subtype of acute myeloid leukemia

A new study shows that the activity of a particular gene can identify people who have a more lethal form of acute myeloid leukemia, singling out those patients who should receive more intense therapy.

10 Jul 2007

Gene therapy offers promising approach to tackle pancreatic cancer

A molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumors, inhibits metastasis, and prolongs survival with virtually no toxicity, researchers from The University of Texas M. D. Anderson Cancer Center report in the July 9 edition of Cancer Cell.

10 Jul 2007

Debate on folic acid fortification

Since the institution of nationwide folic acid fortification of enriched grains in the mid 1990s, the number of infants born in the United States and Canada with neural tube defects has declined by 20 percent to 50 percent.

10 Jul 2007

Potential new treatment pathway for Parkinson's

In the vast majority of Parkinson's disease (PD) patients, the disorder arises not because of a genetic defect, but because some external insult triggers the death of dopamine-producing neurons.

9 Jul 2007