Laboratory News and Research

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Teens' exploratory behavior linked to enhanced psychological well-being and larger social networks

Teenagers become more exploratory in their behaviors with age, becoming increasingly likely to visit new places over time, finds a new study.

15 Sep 2022

Machine learning can help create proteins much more accurately, quickly than previously possible

Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design.

15 Sep 2022

UCLA professor wins NAM award for pioneering research and leadership in autism genetics

Dr. Daniel Geschwind, the Gordon and Virginia MacDonald Distinguished Professor of Human Genetics, Neurology and Psychiatry at UCLA, was awarded the National Academy of Medicine's (NAM) 2022 Rhoda and Bernard Sarnat International Prize in Mental Health in recognition of his pioneering research and leadership in autism genetics.

15 Sep 2022

Scientists develop and test a new model of traumatic brain injury in zebrafish

A group of scientists, which included researchers from the Ural Federal University (UrFU), have developed and successfully tested a new model of traumatic brain injury (TBI) in zebrafish.

15 Sep 2022

BU researcher awarded $7.2 million grant to develop mAb-based contraceptive products

Deborah Jean Anderson, PhD, professor of medicine at Boston University School of Medicine, has received a four-year, $7.2 million grant from the NIH's National Institute of Child Health and Human Development renewing support for a Contraceptive Research Center at BUSM to further her research to develop innovative monoclonal antibody (mAb)-based contraceptive and multipurpose prevention technology (MPT) products.

15 Sep 2022

Vaccine-derived poliovirus 2 detected in environmental samples in the UK and USA

Over the last few months, poliovirus 2 derived from the strain used in the Sabin vaccine (oral polio vaccine) has been repeatedly detected in environmental samples in the USA as well as in the UK. What does this signify?

15 Sep 2022

Concern over two cases of monkeypox-related neurological complications in the U.S.

A new study published in the CDC's Morbidity and Mortality Weekly Report analyzed two people with encephalomyelitis associated with monkeypox disease in Colorado and DC during the current outbreak.

15 Sep 2022

Tufts researchers use machine learning to identify new drug cocktails against tuberculosis

Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year.

14 Sep 2022

Scientists identify two distinct subtypes of obesity

A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication.

14 Sep 2022

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration.

14 Sep 2022

Newborns get routine heel blood tests, but should states keep those samples

Close to 4 million babies are born in the United States every year, and within their first 48 hours nearly all are pricked in the heel so their blood can be tested for dozens of life-threatening genetic and metabolic problems.

14 Sep 2022

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

Through extensive single-cell analysis, researchers at The University of Texas MD Anderson Cancer Center have created a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, highlighting previously unappreciated roles these immune cells play in tumor development and treatment outcomes.

13 Sep 2022

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

Up to three quarters of patients receiving cancer chemotherapy suffer from "chemo brain" - a long-term side effect that makes it harder to remember things, maintain attention, and learn new information. When it strikes children, whose brains are still developing, their schoolwork and self-esteem may suffer.

13 Sep 2022

Experimental drug prolongs survival, improves muscle function in mice severe Duchenne muscular dystrophy

Researchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne muscular dystrophy (DMD).

13 Sep 2022

Discoveries about embryonic blood stem cell creation may solve donor blood stem cell shortages

Making stem cells from a patient’s adult cells – rather than human embryos – is one of the holy grails in modern medicine treatments. New research brings us two steps closer.

13 Sep 2022

What is the effectiveness of tecovirimat for treatment of monkeypox?

Researchers assessed the effectiveness of tecovirimat in monkeypox treatment in a new study.

13 Sep 2022

Brain organoids shed light into the evolution of the human brain

Animal studies on great apes have long been banned in Europe for ethical reasons. For the question pursued here, so-called organoids, i.e. three-dimensional cell structures a few millimeters in size that are grown in the laboratory, are an alternative to animal experiments.

13 Sep 2022

Molecular explanation for the contribution of autophagy to BAT energy metabolism

Obesity is a growing global health problem and its prevalence has tripled since 1975. More than 650 million people are affected by this condition worldwide, and 28% of people in Spain over 18 years of age have this complex pathology. Obesity is linked to conditions such as type II diabetes, cardiovascular disease, osteoarthritis, and certain forms of cancer.

13 Sep 2022

False positive monkeypox tests in low-risk patients with no exposures

Researchers reported three monkeypox diagnoses presenting atypical rashes.

13 Sep 2022

Study investigates BMI, race, and lung cancer diagnosis relationships

Lung cancer is the leading cause of cancer death in the US, making up 25% of cancer deaths. With obesity rates simultaneously rising, researchers have investigated the connections between cancer risk and body mass index (BMI). Unlike most other cancer types, where higher BMI is associated with increased risk of cancer, research has established that paradoxically people with higher BMI have lower rates of lung cancer diagnosis.

13 Sep 2022

Laboratory News and Research

Teens' exploratory behavior linked to enhanced psychological well-being and larger social networks

Machine learning can help create proteins much more accurately, quickly than previously possible

UCLA professor wins NAM award for pioneering research and leadership in autism genetics

Scientists develop and test a new model of traumatic brain injury in zebrafish

BU researcher awarded $7.2 million grant to develop mAb-based contraceptive products

Vaccine-derived poliovirus 2 detected in environmental samples in the UK and USA

Concern over two cases of monkeypox-related neurological complications in the U.S.

Tufts researchers use machine learning to identify new drug cocktails against tuberculosis

Scientists identify two distinct subtypes of obesity

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

Newborns get routine heel blood tests, but should states keep those samples

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

Experimental drug prolongs survival, improves muscle function in mice severe Duchenne muscular dystrophy

Discoveries about embryonic blood stem cell creation may solve donor blood stem cell shortages

What is the effectiveness of tecovirimat for treatment of monkeypox?

Brain organoids shed light into the evolution of the human brain

Molecular explanation for the contribution of autophagy to BAT energy metabolism

False positive monkeypox tests in low-risk patients with no exposures

Study investigates BMI, race, and lung cancer diagnosis relationships

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