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FDA clears St. Jude Medical's AMPLATZER Vascular Plug 4 for transcatheter embolization

St. Jude Medical, Inc., a global medical device company, today announced it has received U.S. Food and Drug Administration (FDA) clearance and will immediately launch the AMPLATZER Vascular Plug 4 (AVP 4) for use in transcatheter embolization procedures (minimally invasive procedures that involve the selective blocking of blood vessels) within the peripheral vasculature.

18 Jun 2012

Cancer publishes Aeterna Zentaris' perifosine Phase 2 trials in RCC

Aeterna Zentaris Inc. today announced that data from two Phase 2 trials in renal cell carcinoma (RCC) for the Company's oral anticancer drug, perifosine, have been published in the June 2012 issue of Cancer, a publication of the American Cancer Society.

18 Jun 2012

Research roundup: Best health care for homeless, new business model for pharma

The cost and coordination of health care for homeless individuals can be a challenge for states. But as this brief describes, establishing supportive housing - which provides social services, usually on site - "can help improve health, increase survival rates, foster mental health recovery, and reduce alcohol and drug use."

16 Jun 2012

St. Michael's to investigate new treatments for prevention of brain injury complications

St. Michael's Hospital has been awarded up to $700,000 from the Federal Economic Development Agency of Southern Ontario to investigate new treatments to prevent complications following certain brain injuries.

16 Jun 2012

Prevena Incision Management System may help decrease incidence of groin SSIs

Kinetic Concepts, Inc. announced today that evidence presented at the Society for Vascular Surgery Conference in Washington, D.C. on June 8, 2012 suggests the Prevena™ Incision Management System, when combined with standard perioperative infection prevention and meticulous surgical technique, may help decrease the incidence of groin surgical site infections (SSIs) in patients undergoing vascular procedures.

16 Jun 2012

Psoriasis TNF-α therapeutic effects mediated by MSC antioxidant reduction

The therapeutic effects of tumor necrosis factor-α inhibitors in psoriasis occur through a reduction in the antioxidant response of mesenchymal stem cells, suggest study findings.

15 Jun 2012

Research examines link between metabolic syndrome and cognitive disorders

No effective treatments are currently available for the prevention or cure of Alzheimer's disease (AD), the most frequent form of dementia in the elderly. The most recognized risk factors, advancing age and having the apolipoprotein E Ɛ4 gene, cannot be modified or treated. Increasingly, scientists are looking toward other risk factors to identify preventive and therapeutic strategies.

15 Jun 2012

CardioFocus, CryoLife resolve outstanding patent dispute

CryoLife, Inc., a leading medical device company focused on cardiac and vascular surgery, announced today that it has entered into a settlement agreement with CardioFocus, Inc. ending the outstanding patent dispute between CryoLife's wholly owned subsidiary, Cardiogenesis Corporation, and CardioFocus that was pending in the United States District Court of Massachusetts.

15 Jun 2012

Transplantation of tissue-engineered vein is a success and offers hope for patients who lack suitable veins for dialysis or bypass surgery

The first biologically tissue-engineered vein grown from a patient’s own stem cells has been successfully transplanted into a 10-year-old girl with portal vein obstruction, dramatically enhancing her quality of life.

15 Jun 2012

Unifying theory on causes of cancer metastases

A unifying theory on the causes of cancer metastases has been proposed by Alexander R.A. Anderson, Ph.D., chair of Integrated Mathematical Oncology at Moffitt Cancer Center, and Jacob Scott, M.D., a Moffitt Radiation Oncology Program resident that is studying for his Ph.D. at the University of Oxford Centre for Mathematical Biology.

15 Jun 2012

Sanovas receives U.S. patent allowance for microsurgical lung cancer technology

Sanovas, Inc., a medical technology company focused on developing and commercializing next-generation micro-invasive diagnostics, devices and drug delivery technologies, today announced that it has received a Notice of Allowance from the United States Patent and Trademark Office for its first patent relating to systems and methods for the removal of unwanted biological material, such as tissue growths and tumors, in hard-to-reach bodily cavities.

15 Jun 2012

CryoLife reaches full settlement in Medafor lawsuit

CryoLife, Inc., a leading medical device company focused on cardiac and vascular surgery, announced today that it has reached full settlement of the outstanding CryoLife, Inc. v. Medafor, Inc. lawsuit that was pending in the Northern District Court of Georgia.

15 Jun 2012

Minimally invasive procedure to treat high blood pressure

A radically different approach to treating high blood pressure – using a minimally invasive procedure – is being evaluated as part of a Pivotal Phase III 90-site national trial that includes The Carl H. and Edyth Lindner Center for Research and Education at The Christ Hospital.

14 Jun 2012

Tooth scaling reduces CV disease risk

Taiwanese study results show that undergoing tooth scaling significantly reduces the risk for future myocardial infarction, stroke, and total cardiovascular events.

14 Jun 2012

New analogues effective in inhibiting NOS activity in Parkinson models

University of Granada researchers have tested melatonin analogues in rats as it inhibits the enzyme nitric oxide synthase (NOS), which is involved in the development of conditions as inflammatory bowel disease, septic shock or rheumatoid arthritis, as well as in neurodegenerative conditions as Huntington's disease, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

14 Jun 2012

Hysterectomy may increase risk of cardiovascular disease in postmenopausal women

Estrogen-deficient, postmenopausal women who have had their uterus removed appear to have stiffer arteries compared to similar women who have not had a hysterectomy, according to new research from the University of Colorado School of Medicine.

14 Jun 2012

ACS honors Boston pediatric surgeon with 2012 Jacobson Innovation Award

W. Hardy Hendren III, MD, FACS, FRCS (Ire, Eng, Glas) (Hon), a pediatric surgeon from Boston, Mass., received the 2012 Jacobson Innovation Award of the American College of Surgeons (ACS) at a dinner held in his honor tonight in Chicago, Ill.

14 Jun 2012

Mixed picture for pulse pressure effect on surgical outcomes

Two studies published in Anesthesia and Analgesia have muddied the water regarding the effect of preoperative pulse pressure on perioperative outcomes.

13 Jun 2012

Rising blood sugar points to developing stroke risk

People with prediabetes have a somewhat increased risk for stroke, say the authors of a meta-analysis.

13 Jun 2012

Short-term intensive weight management program effective alternative to bariatric surgery

A study by a team of clinicians and researchers at the Joslin Diabetes Center in Boston has shown for the first time that patients with diabetes who enrolled in a short-term intensive weight management program were able to lose weight and keep it off on their own for four years.

13 Jun 2012