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Research roundup: Pricing and the SHOP exchange; health use in rural vs. urban areas; the health law and AIDS care

Each week, KHN compiles a selection of recently released health policy studies and briefs.

11 Nov 2013

Research provides new understanding of the effects of race on heart disease

Thomas Jefferson University researchers have discovered that the formation of blood clots follows a different molecular route in African Americans versus European Americans, providing a new understanding of the effects of race on heart disease. The finding could one day help doctors provide more individualized treatment of heart disease and other blood-clot-related illnesses, according to research publishing online November 10th in Nature Medicine.

11 Nov 2013

Treatment with rheumatoid arthritis drug saved transplanted kidney and achieved remission

A drug approved for the treatment of rheumatoid arthritis may also turn out to be the first targeted therapy for one of the most common forms of kidney disease, a condition that almost inevitably leads to kidney failure.

11 Nov 2013

FOXO3 transcription factor may protect against alcohol-induced liver injury

New data suggest that the transcription factor FOXO3 may protect against alcohol-induced liver injury. Researchers determined that alcohol given to mice deficient in FOXO3 caused severe liver injury resembling human alcoholic hepatitis.

11 Nov 2013

Penn Medicine awarded $1.5M to study health care disparities among people with disabilities

The Perelman School of Medicine at the University of Pennsylvania has been awarded $1.5 million by The Patient-Centered Outcomes Research Institute to launch the Mrs. A and Mr. B Project to study health care disparities among people with disabilities. A collaborative research effort with Virtual Ability, Inc., the study aims to provide patients with information that will help them make more informed decisions about their medical care.

11 Nov 2013

New therapeutic at-home gaming program for stroke patients

Researchers at The Ohio State University Wexner Medical Center have developed a therapeutic at-home gaming program for stroke patients who experience motor weakness affecting 80 percent of survivors.

11 Nov 2013

Genetic factors put African Americans with CKD at greater risk for end-stage renal disease

Genetic factors in African Americans with chronic kidney disease put them at a greater risk for end-stage renal disease compared to white Americans, according to a new study released today in the New England Journal of Medicine.

11 Nov 2013

New evidence shows particulate matter exposure associated with kidney damage

Many first responders working at Ground Zero following the 9/11 tragedy were exposed to cement dust, smoke, glass fibers, and heavy metals. Exposure to high levels of such particulate matter caused significant damage to first responders' kidneys, according to research presented at ASN Kidney Week 2013 November 9 at the Georgia World Congress Center in Atlanta, GA.

11 Nov 2013

Researchers reveal that reduction in mitochondrial DNA may lead to metastasis of breast cancer cells

For years, scientists have observed that tumor cells from certain breast cancer patients with aggressive forms of the disease contained low levels of mitochondrial DNA. But, until recently, no one was able to explain how this characteristic influenced disease progression.

11 Nov 2013

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

A team of scientists that includes Saint Louis University researchers has identified a new way to intervene in the molecular and cellular cascade that causes fibrosis - a condition where the body's natural process of forming scars for wound healing goes into overdrive and causes diseases.

11 Nov 2013

Studies highlight potential negative effects of soft drinks, sugar on kidney health

Two new studies highlight the potential negative effects that soft drinks and sugar can have on kidney health. Results of these studies will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

11 Nov 2013

Recent studies suggest that controlling dietary acid intake may help improve kidney health

Three new studies suggest that controlling dietary acid intake could help improve kidney health. Results of these studies will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

11 Nov 2013

Researchers identify novel therapeutic approach for most frequent genetic cause of ALS

A team of scientists led by researchers from the University of California, San Diego School of Medicine and Ludwig Institute for Cancer Research have identified a novel therapeutic approach for the most frequent genetic cause of ALS, a disorder of the regions of the brain and spinal cord that control voluntary muscle movement, and frontal temporal degeneration, the second most frequent dementia.

10 Nov 2013

Adequate vitamin D levels vital for maintaining the health of kidney transplant recipients

Adequate vitamin D levels are important for maintaining kidney transplant recipients' health, according to a study that will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

10 Nov 2013

Genetic variations in African Americans with kidney disease contribute to rapid decline in kidney function

New research provides direct evidence that genetic variations in some African Americans with chronic kidney disease contribute to a more rapid decline in kidney function compared with white Americans.

10 Nov 2013

Tissue scarring may help develop new treatments for patients with damaged organs

Patients with damaged organs could be helped by new treatments after scientists have discovered how tissues scar.

10 Nov 2013

Breast cancer drug appears to protect cells against UV radiation, inflammation

Exemestane, a synthetic steroid drug widely prescribed to fight breast cancers that thrive on estrogens, not only inhibits the production of the hormone, but also appears to protect cells throughout the body against damage induced by UV radiation, inflammation and other assaults, according to results of research by Johns Hopkins scientists.

8 Nov 2013

BW's Primary Healthcare Advancement Program to address nationwide shortage

BW's Primary Healthcare Advancement Program is a distinctive pre-med track focused on disease prevention and the development of future primary care physicians to address a nationwide shortage in the field.

8 Nov 2013

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

An innovative Northwestern Medicine- research program investigating if stem cells may be the key to allowing organ transplant patients to stop taking immunosuppressive drugs has received $12 million in research funding. The grant will allow researchers to finish Phase II of the clinical trials and begin Phase III.

8 Nov 2013

Gladstone-led study sheds light on critical molecular process

One of biology's most fundamental processes is something called transcription. It is just one step of many required to build proteins-and without it life would not exist. However, many aspects of transcription remain shrouded in mystery. But now, scientists at the Gladstone Institutes are shedding light on key aspects of transcription, and in so doing are coming even closer to understanding the importance of this process in the growth and development of cells-as well as what happens when this process goes awry.

8 Nov 2013

Medicine News and Research

Research roundup: Pricing and the SHOP exchange; health use in rural vs. urban areas; the health law and AIDS care

Research provides new understanding of the effects of race on heart disease

Treatment with rheumatoid arthritis drug saved transplanted kidney and achieved remission

FOXO3 transcription factor may protect against alcohol-induced liver injury

Penn Medicine awarded $1.5M to study health care disparities among people with disabilities

New therapeutic at-home gaming program for stroke patients

Genetic factors put African Americans with CKD at greater risk for end-stage renal disease

New evidence shows particulate matter exposure associated with kidney damage

Researchers reveal that reduction in mitochondrial DNA may lead to metastasis of breast cancer cells

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

Studies highlight potential negative effects of soft drinks, sugar on kidney health

Recent studies suggest that controlling dietary acid intake may help improve kidney health

Researchers identify novel therapeutic approach for most frequent genetic cause of ALS

Adequate vitamin D levels vital for maintaining the health of kidney transplant recipients

Genetic variations in African Americans with kidney disease contribute to rapid decline in kidney function

Tissue scarring may help develop new treatments for patients with damaged organs

Breast cancer drug appears to protect cells against UV radiation, inflammation

BW's Primary Healthcare Advancement Program to address nationwide shortage

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

Gladstone-led study sheds light on critical molecular process

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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