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Study identifies urinary biomarker that may help monitor progression of ALS

A study in Neurology suggests that analyzing levels of the protein p75ECD in urine samples from people with amyotrophic lateral sclerosis (ALS) may help monitor disease progression as well as determine the effectiveness of therapies.

22 Mar 2017

SPECT imaging may not be suitable for monitoring Parkinson's disease, study shows

When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. A new study conducted in Turku, Finland, shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.

22 Mar 2017

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Translational Therapeutics at the Perelman School of Medicine at the University of Pennsylvania, has received the 2017 Scientific Innovations Award from the Chicago-based Brain Research Foundation, which supports research for preventing and treating neurological diseases.

22 Mar 2017

New study shows how the brain looks at the world in 3D

We live in a three-dimensional world, but everything we see is first recorded on our retinas in only two dimensions.

21 Mar 2017

Study may signal major shift in understanding of how the cerebellum encodes information

It's the part of the brain that makes sure you cannot tickle yourself. The cerebellum, an apple-sized region near the base of the skull, senses that your own fingers are the ones trying to tickle, and cancels your usual response.

21 Mar 2017

Parasitic fish offers unique insights into evolution of gut neurons in ancient vertebrates

Lamprey are slimy, parasitic eel-like fish, one of only two existing species of vertebrates that have no jaw. While many would be repulsed by these creatures, lamprey are exciting to biologists because they are so primitive, retaining many characteristics similar to their ancient ancestors and thus offering answers to some of life's biggest evolutionary questions

21 Mar 2017

Study: Treatment window for Fragile X syndrome likely remains open into maturity after childhood

Brain samples from humans show that the treatment window for Fragile X syndrome likely remains open well into maturity after childhood, when previous tests with mice indicated it might close, according to a new Drexel University-led study.

21 Mar 2017

Mouse study provides target for development of faster-acting antidepressant medications

Standard antidepressant medications don't work for everyone, and even when they do they are slow to kick in. In an effort to find better depression treatments, researchers at University of California San Diego School of Medicine discovered that inhibiting an enzyme called Glyoxalase 1 (GLO1) relieves signs of depression in mice.

21 Mar 2017

Salk scientists develop new way to find responders to lithium therapy

For roughly one-third of people diagnosed with bipolar disorder, lithium is a miracle drug, effectively treating both their mania and depression. But once someone is diagnosed, it can take up to a year to learn whether that person will be among the 30 percent who respond to lithium or the 70 percent who do not.

21 Mar 2017

Biologists discover secondary set of odor sensors in malaria mosquitoes

Biologists who study the malaria mosquito's 'nose' have found that it contains a secondary set of odor sensors that seem to be specially tuned to detect humans. The discovery could aid efforts to figure out how the insects target humans and develop a preference for them.

17 Mar 2017

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Led by professor Ludo Van Den Bosch, scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).

17 Mar 2017

Study finds reductions in volume of gray matter in the brains of children with obstructive sleep apnea

A study comparing children between 7 and 11 years of age who have moderate or severe obstructive sleep apnea to children the same age who slept normally, found significant reductions of gray matter - brain cells involved in movement, memory, emotions, speech, perception, decision making and self-control - in several regions of the brains of children with sleep apnea.

17 Mar 2017

Fat cells take over production of uridine from liver during fasting

How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks.

17 Mar 2017

Researchers use animal model to study brain abnormality in human TD patients

Thanatophoric dysplasia (TD) is an intractable disease designated by Ministry of Welfare, Health and Labor of Japan, causing severe abnormalities of bones and the brain.

17 Mar 2017

Electroacupuncture triggers neurological mechanism to promote tissue repair and relieve pain, study shows

A study led by Indiana University School of Medicine researchers demonstrates how electroacupuncture triggers a neurological mechanism that can help promote tissue repair and relieve injury-induced pain.

16 Mar 2017

MPFI researchers develop new tool to study CaMKII kinetics in learning and memory

As we learn, the structure of individual neurons in our brains change to strengthen important connections and weaken less important ones, a process known as structural plasticity.

16 Mar 2017

Neuroscientists elucidate how serotonin helps to deal with unfamiliar changing environment

Serotonin, one of the major chemical messengers serving neuronal communication, is usually associated with the direct regulation of affective states and mood in general.

16 Mar 2017

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

Researchers at Beth Israel Deaconess Medical Center have gained new insight into the genetic and neuronal circuit mechanisms that may contribute to impaired sociability in some forms of Autism Spectrum Disorder.

16 Mar 2017

UB research yields neural crest cells from adult skin cells without genetic modification

A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain.

15 Mar 2017

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder.

14 Mar 2017

Neurons News and Research

Study identifies urinary biomarker that may help monitor progression of ALS

SPECT imaging may not be suitable for monitoring Parkinson's disease, study shows

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

New study shows how the brain looks at the world in 3D

Study may signal major shift in understanding of how the cerebellum encodes information

Parasitic fish offers unique insights into evolution of gut neurons in ancient vertebrates

Study: Treatment window for Fragile X syndrome likely remains open into maturity after childhood

Mouse study provides target for development of faster-acting antidepressant medications

Salk scientists develop new way to find responders to lithium therapy

Biologists discover secondary set of odor sensors in malaria mosquitoes

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Study finds reductions in volume of gray matter in the brains of children with obstructive sleep apnea

Fat cells take over production of uridine from liver during fasting

Researchers use animal model to study brain abnormality in human TD patients

Electroacupuncture triggers neurological mechanism to promote tissue repair and relieve pain, study shows

MPFI researchers develop new tool to study CaMKII kinetics in learning and memory

Neuroscientists elucidate how serotonin helps to deal with unfamiliar changing environment

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

UB research yields neural crest cells from adult skin cells without genetic modification

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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