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Characteristics and outcomes in patients hospitalized with COVID-19 in South Africa

A new research letter assessed patients hospitalized with a positive SARS-CoV-2 test during the fourth wave compared to the previous waves.

4 Jan 2022

Modeling shows SARS-CoV-2 Omicron will place a severe burden on UK's health services

Researchers use data and a mathematical model to determine the impact of the SARS-CoV-2 Omicron variant on future risk of infection.

3 Jan 2022

CDC report shows COVID vaccines safe for children, serious side effects rare

Researchers determine the characteristics and clinical outcomes of COVID-19 in children and adolescents 18 years or younger.

3 Jan 2022

Olfactory receptor gene may play a role in breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital (MGH) have found.

3 Jan 2022

Scientists analyze the causes of deaths and disabilities in Colorado over a 29-year period

Scientists at Colorado State University used one of the most comprehensive global health datasets in the world to analyze the causes of deaths and disabilities in Colorado over a 29-year period, from 1990 to 2019.

3 Jan 2022

Hypertension-related maternal mortality rates continue to increase in the United States

Chronic hypertension is contributing substantially to maternal deaths in the United States, with particular risk among Black women, according to new research from Rutgers Robert Wood Johnson Medical School's Department of Obstetrics, Gynecology and Reproductive Sciences.

3 Jan 2022

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

A new study used in silico approaches for designing a next-generation CD40-targeting vaccine, CD40.

31 Dec 2021

SARS-CoV-2 infection and immunity in pregnancy and fetal development

A review conducted by a team of researchers from the Icahn School of Medicine at Mount Sinai, the University of Colorado, and Active Motif, Incorporated compiles information on SARS-CoV-2 virology, in utero transmission from infected pregnant mothers to fetuses, new findings on possible methods of SARS-CoV-2 cellular trafficking through exosomes, and the transcriptomic effects of SARS-CoV-2 infection, in order to inform future studies aimed at a better understanding of COVID-19 and the development of therapeutic solutions against SARS-CoV-2.

30 Dec 2021

Study shows varying population immunity against SARS-CoV-2

Researchers analyzed the combined distribution of COVID-19 vaccination and prior SARS-CoV-2 infection in each state and county in the US since the beginning of the COVID-19 epidemic to estimate the changes in the population immunity during this period.

30 Dec 2021

Orphanhood decreases with the availability of antiretroviral therapy and male circumcision

Researchers at Columbia University Mailman School of Public Health found marked decreases in orphanhood particularly double orphanhood, among adolescents in Rakai, Uganda, corresponding with the availability of antiretroviral therapy (ART) beginning in 2004 and of male medical circumcision in 2007.

30 Dec 2021

Black men with prostate cancer may have improved response to radiation therapy than white men

UCLA Jonsson Comprehensive Cancer Center researchers leading a meta-analysis of seven randomized trials found an "unexpected result": Although Black men appeared to have more aggressive disease when they enrolled in clinical trials of radiation therapy for prostate cancer, their treatment outcomes and disease-specific outcomes were better than those of their white counterparts.

30 Dec 2021

Omicron analysis shows no clear evidence for increased virulence or lethality

Researchers conducted a genomic sequencing and epidemiological correlation analysis of the SARS-CoV-2 Omicron variant.

29 Dec 2021

An evaluation of the association between COVID vaccination and myocarditis in 42 million people aged 13 or older

A new study posted to the medRxiv* pre-print server included individuals over 13 years of age receiving the third vaccine dose to further evaluate the association between myocarditis and COVID-19 vaccination or infection. The study took place from December 1, 2020, to November 15, 2021.

28 Dec 2021

SARS-CoV-2 Omicron variant neutralized by third BNT162b2 booster shot

A new preprint* research paper under consideration at Nature Portfolio Journal assesses the susceptibility of the Omicron variant to neutralizing antibody response after booster immunization.

28 Dec 2021

Double-dose mRNA COVID vaccines effective among dialysis patients

Researchers assess the impact of lesser initial vaccine response and subsequent waning antibody levels on clinical outcomes among maintenance dialysis.

28 Dec 2021

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19.

28 Dec 2021

Retransplantation may provide better survival over dialysis after failed first kidney transplant

Kidney transplantation is the preferred therapy after kidney failure, but kidneys transplanted from deceased donors often do not last for the rest of a recipient's life.

28 Dec 2021

APOE4 allele gene linked to increased risk of severe COVID-19

A study conducted at the University of Helsinki and the Helsinki University Hospital suggests that the APOE4 allele may also increase cerebral microhemorrhages related to COVID-19 and associate with mental fatigue related to long COVID.

27 Dec 2021

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

The first study to evaluate the clinical characteristics and outcomes of fully vaccinated patients with cancer who had breakthrough COVID-19 infections indicates they remained at high risk for hospitalization and death.

26 Dec 2021

Children with pre-existing immunity to common cold demonstrate better protection against COVID-19

New data shows that, compared to adults, children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preferentially activate pre-existing acquired immunity to prevalent common cold coronaviruses that cross-react with SARS-CoV-2 and protect them from severe disease.

24 Dec 2021

Mortality News and Research

Characteristics and outcomes in patients hospitalized with COVID-19 in South Africa

Modeling shows SARS-CoV-2 Omicron will place a severe burden on UK's health services

CDC report shows COVID vaccines safe for children, serious side effects rare

Olfactory receptor gene may play a role in breast cancer metastasis to the brain

Scientists analyze the causes of deaths and disabilities in Colorado over a 29-year period

Hypertension-related maternal mortality rates continue to increase in the United States

Impact of a pan-sarbecovirus dendritic-cell targeting vaccine on SARS-CoV-2 variants

SARS-CoV-2 infection and immunity in pregnancy and fetal development

Study shows varying population immunity against SARS-CoV-2

Orphanhood decreases with the availability of antiretroviral therapy and male circumcision

Black men with prostate cancer may have improved response to radiation therapy than white men

Omicron analysis shows no clear evidence for increased virulence or lethality

An evaluation of the association between COVID vaccination and myocarditis in 42 million people aged 13 or older

SARS-CoV-2 Omicron variant neutralized by third BNT162b2 booster shot

Double-dose mRNA COVID vaccines effective among dialysis patients

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

Retransplantation may provide better survival over dialysis after failed first kidney transplant

APOE4 allele gene linked to increased risk of severe COVID-19

Cancer patients who had breakthrough COVID-19 remain at high risk for hospitalization, death

Children with pre-existing immunity to common cold demonstrate better protection against COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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