in vitro News and Research

RSS

Transplanted fat cells restore function after spinal cord injury

A study published in the current issue of Cell Transplantation (Vol.17, No. 8) suggests that mature adipocytes - fat cells - could become a source for cell replacement therapy to treat central nervous system disorders.

10 Dec 2008

Xencor presents data on anti-CD19 and anti-CD40 antibodies

Xencor, Inc. presented results Sunday at the 50th Annual Meeting of the American Society of Hematology from pre-clinical studies evaluating XmAb 5574, a monoclonal antibody engineered using Xencor's XmAb Fc technologies that targets the antigen CD19.

10 Dec 2008

$EntreMed starts trial of ENMD-2076 in refractory multiple myeloma patients$

EntreMed starts trial of ENMD-2076 in refractory multiple myeloma patients

EntreMed, Inc. has announced that it has initiated a Phase 1 study of ENMD-2076 in refractory multiple myeloma patients.

10 Dec 2008

Vitamin E supplementation may reduce inflammation in the brain

With up to half of a person's body mass consisting of skeletal muscle, chronic inflammation of those muscles - which include those found in the limbs - can result in significant physical impairment.

5 Dec 2008

Researchers develop human embryonic stem cell-based system for modeling ALS

Long thought of as mere bystanders, astrocytes are crucial for the survival and well-being of motor neurons, which control voluntary muscle movements.

3 Dec 2008

Prototype blood scanner detects even faint indicators of cancer

A team led by Stanford researchers has developed a prototype blood scanner that can find cancer markers in the bloodstream in early stages of the disease, potentially allowing for earlier treatment and dramatically improved chances of survival.

3 Dec 2008

Nitric oxide can change computational ability of the brain

Research from the Medical Research Council (MRC) Toxicology Unit at the University of Leicester shows that nitric oxide (NO) can change the computational ability of the brain.

26 Nov 2008

MorphoSys and Galapagos enter alliance to co-develop novel therapeutic antibodies in bone and joint disease

MorphoSys AG and Galapagos NV announced today the launch of a long term co-development alliance aimed at discovering and developing antibody therapies based on novel modes of action in bone and joint disease, including rheumatoid arthritis, osteoporosis and osteoarthritis.

26 Nov 2008

New advance in the treatment of sickle cell anaemia

Sickle cell anaemia is a genetic disease characterised by the sickling of red blood cells in patients suffering from hypoxia (around 100,000 cases in Europe and North America).

25 Nov 2008

Novel device enhances efficacy of standard chemotherapy

NovoCure Ltd. presented results yesterday evaluating the Novo-TTF device in vitro and in a pilot clinical trial that showed the device enhanced the efficacy of standard chemotherapy (temozolomide) treatment in newly-diagnosed glioblastoma multiforme (GBM) patients.

24 Nov 2008

Long-term use of a macrolide antibiotic reduce COPD exacerbations, raise questions

Long-term use of a macrolide antibiotic may reduce the frequency of exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) by as much as 35 percent, according to a London-based study.

21 Nov 2008

Viral Genetics completes acquisition of V-Clip Pharmaceuticals

Viral Genetics, Inc. has announced it has completed its acquisition of V-Clip Pharmaceuticals, Inc. ("V-Clip").

19 Nov 2008

More data released on key diabetes genes

One of the most reliable indicators to predict that a person will develop type 2 diabetes is the presence of insulin resistance.

19 Nov 2008

Nontoxic nanoparticle delivers and tracks drugs

A nontoxic nanoparticle developed by Penn State researchers is proving to be an all-around effective delivery system for both therapeutic drugs and the fluorescent dyes that can track their delivery.

18 Nov 2008

Targanta Therapeutics announces posting of briefing documents for review of FDA

Targanta Therapeutics Corporation announced today that the U.S. Food and Drug Administration (FDA) has posted on its website briefing documents for the November 19, 2008 Anti-Infective Drugs Advisory Committee (AIDAC) meeting.

18 Nov 2008

New evidence on how proteins help cells fix broken DNA

Aucott et al. report the first in vivo experiments on the heterochromatin protein 1 (HP1) family, which sidles up to silent DNA.

17 Nov 2008

How household bleach kills bacteria

Despite the fact that household bleach is commonly used as a disinfectant, exactly how it works to fight bacteria remained an open question.

16 Nov 2008

Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord

Multiple sclerosis is a disease caused by the loss of the myelinated sheath surrounding the nerve fibers of the spinal cord.

12 Nov 2008

Discovery of essential mechanism for maintenance of myelin's structure

In a new study, researchers at the Montreal Neurological Institute (MNI), McGill University, and the University of Montreal have discovered an essential mechanism for the maintenance of the normal structure of myelin, the protective covering that insulates and supports nerve cells (neurons).

12 Nov 2008

Computers used to create predictive models of human disease

Increased use of computers to create predictive models of human disease is likely following a workshop organised by the European Science Foundation (ESF), which urged for a collaborative effort between specialists in the field.

12 Nov 2008