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Discovery sheds light on how forces outside of cells get translated into internal signals

Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities.

21 Oct 2013

COPD investigational treatments: an interview with Dr. Tunde Otulana, Senior Vice President, Clinical Development and Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Inc.

Olodaterol is a long-acting beta2-agonist (LABA) bronchodilator delivered via the Respimat® inhaler. It is being investigated as a once daily maintenance bronchodilator treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

21 Oct 2013

GVI uses Toshiba’s Spot Fluoroscopy to reduce radiation exposure to patients and physicians

Gates Vascular Institute is now able to conduct safer exams using Spot Fluoroscopy, a cardiovascular X-ray dose management technology from Toshiba America Medical Systems, Inc. GVI utilizes Spot Fluoroscopy with its Infinix-i bi-plane to reduce radiation exposure to both patients and physicians.

21 Oct 2013

Researchers discover link between NOX4 enzyme and osteoporosis

Genkyotex, the leading developer of NOX enzyme inhibitors, announced today that a group of collaborators have discovered a link between the enzyme NOX4 and development of osteoporosis.

21 Oct 2013

Breast milk purchased over Internet contained bacteria that can cause illness in infants

Results from a study led by researchers at Nationwide Children's Hospital found more than three-fourths of breast milk samples purchased over the Internet contained bacteria that can cause illness, and frequently exhibited signs of poor collection, storage or shipping practices.

21 Oct 2013

Genetic mutation found to restore translational balance in mice

In a biological quirk that promises to provide researchers with a new approach for studying and potentially treating Fragile X syndrome, scientists at the University of Massachusetts Medical School (UMMS) have shown that knocking out a gene important for messenger RNA (mRNA) translation in neurons restores memory deficits and reduces behavioral symptoms in a mouse model of a prevalent human neurological disease.

21 Oct 2013

Adolescents vaccination for pertussis linked with lower rates of infant hospitalizations

Widespread vaccination of adolescents for pertussis was associated with lower rates of infant hospitalizations for the respiratory infection than would have been expected had teens not been inoculated according to new research in Pediatrics.

21 Oct 2013

New research identifies internal timepiece that accurately gauge age of human organs and tissues

Everyone grows older, but scientists don't really understand why. Now a UCLA study has uncovered a biological clock embedded in our genomes that may shed light on why our bodies age and how we can slow the process.

21 Oct 2013

Scientists find unexpected molecular switch that prompts blood stem cells aging

Scientists report in Nature they have found a novel and unexpected molecular switch that could become a key to slowing some of the ravages of getting older as it prompts blood stem cells to age.

21 Oct 2013

Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

Researchers identify key therapeutic target for cancers driven by KRAS protein

Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

20 Oct 2013

Pfizer announces top-line results from phase 3b studies with Lyrica Capsules

Pfizer Inc. (NYSE:PFE) announced top-line results from two phase 3b, placebo-controlled studies with Lyrica® (pregabalin) Capsules CV in patients with fibromyalgia (FM) and painful diabetic peripheral neuropathy (DPN), respectively.

19 Oct 2013

Community health awareness delivered by paramedics leads to 32% reduction in EMS calls

Emergency Medical Service (EMS) staff are accustomed to responding to emergencies. A study presented today at the Canadian Cardiovascular Congress finds they may be able to prevent many emergencies as well, judging by the preliminary success of a pilot project at a Hamilton building for seniors.

19 Oct 2013

New study guides clinicians and policy makers on cost-effectiveness of anticoagulant drugs

Patients who are responding below par to the anticoagulant drug warfarin have several options. They can undergo even more blood tests to monitor their response to the different dosages of this medication which is prescribed to prevent strokes, or they could start using one of the newer, yet more expensive, anticoagulants on the market.

19 Oct 2013

FDA approves Iroko Pharmaceuticals’ ZORVOLEX capsules

Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, today announced that the U.S. Food and Drug Administration (FDA) has approved ZORVOLEX™ (diclofenac) capsules, a nonsteroidal anti-inflammatory drug (NSAID), for the treatment of mild to moderate acute pain in adults. ZORVOLEX was approved at dosage strengths that are 20 percent lower than currently available diclofenac products.

19 Oct 2013

Thomson Reuters adds Cortellis Clinical Trials Intelligence for drug discovery and development

The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today announced the addition of Clinical Trials Intelligence to the Thomson Reuters CortellisTM suite, the industry's most comprehensive information solution for drug discovery and development.

19 Oct 2013

Valley Presbyterian Hospital doc awarded 2013 Achievement Award in Diabetic Limb Salvage

George Andros, MD, Founder and Medical Director of the Amputation Prevention Center at Valley Presbyterian Hospital, was honored with the MedStar Georgetown 2013 Distinguished Achievement Award in Diabetic Limb Salvage.

19 Oct 2013

Study shows significant link between low dietary fiber intake and cardiometabolic risks

A new study published in the December issue of The American Journal of Medicine shows a significant association between low dietary fiber intake and cardiometabolic risks including metabolic syndrome, cardiovascular inflammation, and obesity.

19 Oct 2013

Boston Medical Center receives 2 research awards from PCORI to study delivery of cancer care

Boston Medical Center (BMC) has been approved to receive two research awards from the Patient-Centered Outcomes Research Institute (PCORI). One will study the delivery of cancer care to patients who face socio-legal barriers and the other will test the effectiveness of integrative medical group visits (IMGV) for treating chronic pain.

19 Oct 2013

CIRM President Steps Down After Six Years

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18 Oct 2013

Medicine News and Research

Discovery sheds light on how forces outside of cells get translated into internal signals

COPD investigational treatments: an interview with Dr. Tunde Otulana, Senior Vice President, Clinical Development and Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Inc.

GVI uses Toshiba’s Spot Fluoroscopy to reduce radiation exposure to patients and physicians

Researchers discover link between NOX4 enzyme and osteoporosis

Breast milk purchased over Internet contained bacteria that can cause illness in infants

Genetic mutation found to restore translational balance in mice

Adolescents vaccination for pertussis linked with lower rates of infant hospitalizations

New research identifies internal timepiece that accurately gauge age of human organs and tissues

Scientists find unexpected molecular switch that prompts blood stem cells aging

Clarified role of signal-relay proteins may help explain spread of cancer

Researchers identify key therapeutic target for cancers driven by KRAS protein

Pfizer announces top-line results from phase 3b studies with Lyrica Capsules

Community health awareness delivered by paramedics leads to 32% reduction in EMS calls

New study guides clinicians and policy makers on cost-effectiveness of anticoagulant drugs

FDA approves Iroko Pharmaceuticals’ ZORVOLEX capsules

Thomson Reuters adds Cortellis Clinical Trials Intelligence for drug discovery and development

Valley Presbyterian Hospital doc awarded 2013 Achievement Award in Diabetic Limb Salvage

Study shows significant link between low dietary fiber intake and cardiometabolic risks

Boston Medical Center receives 2 research awards from PCORI to study delivery of cancer care

CIRM President Steps Down After Six Years

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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