Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

GlaxoSmithKline believes there is no liver safety issue with Avandia (rosiglitazone maleate)

GlaxoSmithKline today issued the following response to a petition filed by Public Citizen to the U.S. Food and Drug Administration (FDA) on Avandia (rosiglitazone maleate), a highly effective therapy for treating type 2 diabetes when used in the appropriate patient population.

31 Oct 2008

Grapes may aid a bunch of heart risk factors

Could eating grapes help fight high blood pressure related to a salty diet? And could grapes calm other factors that are also related to heart diseases such as heart failure? A new University of Michigan Cardiovascular Center study suggests so.

29 Oct 2008

Eating whole grains lowers heart failure risk

About 5 million people in the United States suffer from heart failure (HF). While some reports indicate that changes to diet can reduce HF risk, few large, prospective studies have been conducted.

27 Oct 2008

Bisphosphonates for osteoporosis increase risk for heart problems

People who take bisphosphonates for osteoporosis may be at risk for serious atrial fibrillation (AF), or irregular heartbeats, according to a new study.

27 Oct 2008

Aires Pharmaceuticals signs license agreement with NIH

Aires Pharmaceuticals Inc. today announced the signing of an exclusive license agreement with the U.S. National Institutes of Health for the patented use of a nitric oxide prodrug to treat cardiopulmonary conditions.

22 Oct 2008

New therapy for heart failure

During heart failure the body reacts to the production of the hormone aldosterone. Too much aldosterone can stiffen and damage the muscles of the heart.

15 Oct 2008

Pennsylvania, New Jersey release hospital quality performance reports

Death rates from heart bypass and valve surgeries performed at Pennsylvania hospitals have declined significantly in recent years, according to a Pennsylvania Health Care Cost Containment Council report released on Thursday, the Philadelphia Inquirer reports.

22 Sep 2008

Cardiologists find old-fashioned physical exams just as good for assessing heart failure as new technology

Patient history and physical examination, traditionally the cornerstone diagnostic tool for medical care, may still be among the most accurate and cost-efficient methods to assess patients with congestive heart failure, UT Southwestern Medical Center researchers have found.

17 Sep 2008

Depressed dialysis patients more likely to be hospitalized or die, researcher finds

Dialysis patients diagnosed with depression are nearly twice as likely to be hospitalized or die within a year than those who are not depressed, a UT Southwestern Medical Center researcher has found.

14 Sep 2008

CMS adds children's health care information to Hospital Compare web site

CMS on Wednesday announced that it has updated its Hospital Compare Web site to include information on 30-day mortality rates for the pneumonia and inpatient asthma treatment for children, CQ HealthBeat reports.

5 Sep 2008

Further analysis from ATHENA study showed Multaq (Dronedarone) reduced risk of stroke in patients with atrial fibrillation

The results of a post-hoc analysis of the data from the ATHENA study were presented today at the clinical trial update session of the European Society of Cardiology congress 2008, in Munich, Germany.

3 Sep 2008

Results from the Simvastatin and Ezetimibe in aortic stenosis study

The SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) study has investigated the effects of intensive cholesterol lowering with the combination of simvastatin (40 mg daily) and ezetimibe (10 mg daily) in patients with aortic stenosis.

2 Sep 2008

European guidelines for acute pulmonary embolism

Acute pulmonary embolism (PE) is a relatively common cardiovascular emergency. Clots originating in the leg veins may become detached and obstruct the lung vessels. This obstruction may lead to a rise of pressure in the pulmonary circulation and possibly to life-threatening heart failure.

2 Sep 2008

New guidelines on heart failure

Heart failure is a leading cause of death and hospitalisation and represents a major burden on health services. It is estimated that over 15 million people in Europe suffer from heart failure and the syndrome accounts for over 2% of national expenditure on health. The new guidelines on heart failure from the European Society of Cardiology are eagerly awaited.

2 Sep 2008

New diagnostic tools and biomarkers

Patients presenting shortness of breath on arrival at the emergency department (ED) can gain from improved diagnosis allowing physicians to distinguish congestive heart failure patients from those presenting pneumonia.

1 Sep 2008

Faster heart rate linked to increased heart attack risk

A long-term study has revealed a link between a faster heart rate and the risk of a heart attack and the researchers say that heart disease patients with a pulse of more than 70 beats a minute are most at risk.

1 Sep 2008

DES in diabetic patients

The issue of using or not using DES in patients with diabetes will be debated between Professor Wijns, who discourages DES and Professor Silber, who feels that they should be used.

31 Aug 2008

TIME-CHF Trial: Elderly HF patients do not benefit from intensive medical therapy

Intensified, BNP-guided therapy was no more effective than a standard, symptom-guided approach in elderly heart failure patients in reducing the number of deaths and all-cause hospitalisations. However, the response to this intervention differed significantly between patients aged 60-74 years and those aged ¡Ý75 years. This indicates the need for specific data in this large subset of very old heart failure patients who have been largely excluded from large treatment trials.

31 Aug 2008

The BEAUTIFUL study: Ivabradine and the reduction of cardiovascular events

The results of the much awaited BEAUTIFUL (morBidity-mortality EvAlUaTion of the If inhibitor ivabradine in patients with CAD and left ventricULar dysfunction) trial have shown that coronary artery disease (CAD) patients with left ventricular dysfunction (LVD) and a heart rate more than 70 bpm have a significantly higher risk of cardiovascular death and other cardiovascular events and in these patients (heart rate above 70 bpm) treatment with ivabradine further reduces the risk of the most important coronary events such as fatal and non-fatal myocardial infarction and coronary revascularisation by one third, even when these patients are already receiving optimal therapy.

31 Aug 2008

The GISSI-HF trial: Effects of n-3 PUFA in 6,975 patients with symptomatic chronic heart failure

Researchers involved in the GISSI trial, concluded that simple, safe and cheap treatment with n-3 PUFA can provide a moderate beneficial advantage in terms of mortality and admission to hospital for cardiovascular reasons in patients with chronic heart failure, in a context of usual care.

31 Aug 2008