Blood Cancer News and Research

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New technology could hold key to predicting outcome of blood cancer patients

Technology that can detect the length of small DNA structures in cancer cells could hold the key to predicting the outcome of patients with two different types of blood cancer.

11 May 2017

Scientists launch new virtual platform to aid global search for treatment of leukemia

Finding a cure for a rare type of blood cancer could be accelerated by a new virtual platform that allows researchers easy access to data from patient samples generated by laboratories around the world.

29 Apr 2017

Scientists announce ‘outstanding’ results of new blood cancer study

Scientists have described new results of a blood cancer study as 'outstanding' in tackling previously untreatable forms of chronic lymphocytic leukemia.

27 Apr 2017

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.

26 Apr 2017

Research shows how TET2 protein loss can open door for mutations that drive blood cancers

Imagine this scenario on a highway: A driver starts to make a sudden lane change but realizes his mistake and quickly veers back, too late. Other motorists have already reacted and, in some cases, collide. Meanwhile, the original motorist - the one who caused the problem - drives on.

25 Apr 2017

Scientists develop new tool to analyse single-cell RNA data in pre-malignant blood cancers

Wellcome Trust Sanger Institute scientists and their collaborators have developed a new analysis tool that was able to show, for the first time, which genes were expressed by individual cells in different genetic versions of a benign blood cancer.

29 Mar 2017

Research uncovers vast inequalities in cancer care for older patients with leukaemia

New research conducted by Leukaemia CARE into the lives of older people living with blood cancers has uncovered vast inequalities in cancer care for the elderly compared with younger patients.

28 Mar 2017

Study identifies potential Achilles heel of kinase-driven cancers

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models.

22 Mar 2017

Mayo Clinic researchers find new experimental drug that shrinks tumors in multiple myeloma patients

Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma. The findings are published in Nature Medicine.

8 Mar 2017

Clinical study seeks to examine new combination therapy for treating AML patients

A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.

7 Mar 2017

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Scientists identify potential therapeutic target for aggressive lymphomas

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have identified a possible therapeutic target for 2 types of very aggressive lymphomas.

28 Feb 2017

Scientists reveal how gluten plays role in development of rare form of cancer for coeliac patients

Scientists in The Netherlands have revealed how gluten plays a role in the development of a rare form of cancer, for some people with coeliac disease.

27 Feb 2017

Treating multiple myeloma with rabbit virus eliminates majority of malignant cells, study shows

Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators at the Medical University of South Carolina and elsewhere in an article published online on December 7, 2016 by Molecular Therapy -- Oncolytics.

22 Feb 2017

Researchers examine risk factors for B Cell Non-Hodgkin Lymphoma in Israeli, Palestinian populations

Israeli and Palestinian researchers have conducted a large scale epidemiological study examining risk factors for a form of Non-Hodgkin Lymphoma in these two populations.

21 Feb 2017

Researchers create novel model that reveals cellular, molecular events driving leukemia progression

Mount Sinai researchers have created a novel model that shows the step-by-step progression from normal blood cells to leukemia and its precursor diseases, creating replicas of the stages of the disease to test the efficacy of therapeutic interventions at each stage, according to a study to be published in Cell Stem Cell.

16 Feb 2017

New ‘MAGIC algorithm’ can predict transplant patient’s risk of developing graft-versus-host disease

Researchers at Mount Sinai Health System have discovered a way to predict whether blood cancer patients who received a bone marrow transplant will develop graft-versus-host disease, a common and often lethal complication, according to a study published in JCI Insight.

9 Feb 2017

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.

2 Feb 2017

Researchers design antibody that recognizes and destroys blood cancer stem cells

A protein-sugar molecule, CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) and the related myelodysplastic syndromes.

25 Jan 2017