Embryonic Development News and Research

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Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.

UCSD researchers describe surprising role of protein in embryonic development

Hematopoietic stem cells (HSCs) give rise to all blood and immune cells throughout the life of vertebrate organisms, from zebrafish to humans. But details of their genesis remain elusive, hindering efforts to develop induced pluripotent stem cell (iPSC) replacements that might address a host of blood disorders.

7 Nov 2014

Salk Institute researchers heal injured hearts of living mice

Researchers at the Salk Institute have healed injured hearts of living mice by reactivating long dormant molecular machinery found in the animals' cells, a finding that could help pave the way to new therapies for heart disorders in humans.

7 Nov 2014

UM researchers explain signaling systems that tissues use to communicate at the head-trunk region

Think about the way our bodies are assembled during early development and ask: How do neighboring cells know that they are supposed to become a nerve or a bone cell and how do these tissues find the correct place and alignment? Researchers at the University of Miami (UM) are answering these crucial questions.

5 Nov 2014

Rice-led research shows how migratory cancer cells acquire 'stem-like' properties

In the first study of its kind, Rice University researchers have mapped how information flows through the genetic circuits that cause cancer cells to become metastatic. The research reveals a common pattern in the decision-making that allows cancer cells to both migrate and form new tumors. Researchers say the commonality may open the door to new drugs that interfere with the genetic switches that cancer must flip to form both cancer stem cells and circulating tumor cells -- two of the main players in cancer metastasis.

31 Oct 2014

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

Ludwig Oxford researchers have discovered a key mechanism that governs how cells of the epithelia, the soft lining of inner body cavities, shift between a rigid, highly structured and immobile state and a flexible and motile form.

27 Oct 2014

Preeclampsia study provides pathways for new therapeutic treatments

A team of researchers led by a Wayne State University School of Medicine associate professor of obstetrics and gynecology has published findings that provide novel insight into the cause of preeclampsia, the leading cause of maternal and infant death worldwide, a discovery that could lead to the development of new therapeutic treatments.

27 Oct 2014

High risk for congenital heart defects in Down syndrome provides tool to identify changes in genes

Down syndrome is the most common chromosomal abnormality in humans, involving a third copy of all or part of chromosome 21. In addition to intellectual disability, individuals with Down syndrome have a high risk of congenital heart defects. However, not all people with Down syndrome have them – about half have structurally normal hearts.

25 Oct 2014

NIH presents 2014 New Innovator Award to Penn Medicine researcher

Roberto Bonasio, PhD, an assistant professor of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, and a core member of the Penn Epigenetics Program is one of the recipients of a 2014 New Innovator Award from the National Institutes of Health (NIH).

16 Oct 2014

Scientists discover new clues about drug used in treating blood cancer

Keck Medicine of USC scientists have discovered new clues about a drug instrumental in treating a certain blood cancer that may provide important targets for researchers searching for cures.

26 Sep 2014

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Researchers at Jacksonville's campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons - both significant contributors to this type of dementia.

21 Sep 2014

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.

15 Sep 2014

Clinical trial to assess safety and efficacy of novel monoclonal antibody for CLL patients

Researchers at the University of California, San Diego School of Medicine, in partnership with the California Institute for Regenerative Medicine (CIRM) and Celgene Corporation, a New Jersey-based biopharmaceutical company, have launched a phase 1 human clinical trial to assess the safety and efficacy of a novel monoclonal antibody for patients with chronic lymphocytic leukemia (CLL).

4 Sep 2014

Nasal septum cells can repair human articular cartilage defects

Human articular cartilage defects can be treated with nasal septum cells. Researchers at the University and the University Hospital of Basel report that cells taken from the nasal septum are able to adapt to the environment of the knee joint and can thus repair articular cartilage defects.

30 Aug 2014

Zebrafish and virus help scientists map the living brain

A virus and a zebrafish are helping scientists map the living brain. "You can kinda draw a diagram and see how cells within it are connected in a functioning brain," said Dr. Albert Pan, neuroscientist at the Medical College of Georgia at Georgia Regents University.

26 Aug 2014

Embryonic Development News and Research

Further Reading

UCSD researchers describe surprising role of protein in embryonic development

Salk Institute researchers heal injured hearts of living mice

UM researchers explain signaling systems that tissues use to communicate at the head-trunk region

Rice-led research shows how migratory cancer cells acquire 'stem-like' properties

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

Preeclampsia study provides pathways for new therapeutic treatments

High risk for congenital heart defects in Down syndrome provides tool to identify changes in genes

NIH presents 2014 New Innovator Award to Penn Medicine researcher

Scientists discover new clues about drug used in treating blood cancer

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Clinical trial to assess safety and efficacy of novel monoclonal antibody for CLL patients

Nasal septum cells can repair human articular cartilage defects

Zebrafish and virus help scientists map the living brain

Researchers find roving detection system for treating cancer, Parkinson's disease and ALS

Regulation of stem cells in zebrafish embryos results in surprising insights into Alzheimer's Disease

FGF proteins play broad roles in wound healing

MGH-developed microfluidic device may help study key steps involved in development of tumor metastasis

Anti-EphA3 antibody has anti-tumour effects against solid cancers

Molecule Notch involved in fear memory formation

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