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Researchers discover differences between mice and humans in function of insulin-producing beta cells

Research from King's College in London, UK, and Lund University in Sweden could explain why diabetes drugs which have worked in animal experiments are not equally successful in humans.

4 Jul 2017

New portable device can quickly find markers of sepsis from single drop of blood

A new portable device can quickly find markers of deadly, unpredictable sepsis infection from a single drop of blood.

3 Jul 2017

Finnish mothers carry rare gene variants that protect them from pre-eclampsia, study finds

Researchers at the University of Helsinki, in cooperation with two research groups in the United States, have discovered that some Finnish mothers carry rare gene variants that protect them from pre-eclampsia, also known as toxaemia of pregnancy.

3 Jul 2017

NEI-funded research aims to prevent or reverse progression of cataracts

Research funded by the National Eye Institute aims to reverse progression of cataracts- the most common cause of blindness worldwide- or to prevent them from forming altogether.

30 Jun 2017

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.

30 Jun 2017

Study highlights rate of misdiagnosis in Alzheimer's disease patients with psychosis

People with Alzheimer's disease who experience psychosis--including delusions and hallucinations--are five times more likely to be misdiagnosed with dementia with Lewy bodies compared to patients who do not, new research suggests.

30 Jun 2017

Scientists find new clues to how RSV causes disease

By age 2, most children have been infected with respiratory syncytial virus (RSV), which usually causes only mild cold symptoms. But people with weakened immune systems, such as infants and the elderly, can face serious complications, including pneumonia and -- in some cases -- death.

30 Jun 2017

Study indicates new element involved in genome instability

Genome instability is the main risk factor in the development of tumours in humans. Understanding how, where, when and why these mutations are produced in DNA is one of the great objectives of the global scientific community.

30 Jun 2017

Timing of mutations can have effect on health and disease

A single genetic mutation can lead to completely different diseases, depending on the time and location at which the mutation occurs.

30 Jun 2017

Differential RNA splicing may play role in prostate cancer disparities in African-American men

A form of genetic variation, called differential RNA splicing, may have a role in tumor aggressiveness and drug resistance in African American men with prostate cancer.

30 Jun 2017

Dysfunctional microglia cells contribute to loss of synapses in Alzheimer's disease

Similar to other neurodegenerative disorders, Alzheimer's is a disease in which the cognitive abilities of afflicted persons continuously worsen.

30 Jun 2017

New, improved microcontact printing technology offers big hope for disease detection

OIST researchers develop a simple printing method to create effective disease detection tools.The field of medicine is always on the lookout for better disease diagnostic tools—simpler, faster, and cheaper technologies to enhance patient treatment and outcomes.

30 Jun 2017

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

A multi-disciplinary team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, the Institute of Bioengineering and Nanotechnology of A*STAR, and BioSyM, Singapore-MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

30 Jun 2017

Novel procedure to seal off lymphatic fluid leaks improves symptoms in patients with single-ventricle disease

Focusing on a rare but devastating complication in patients with single-ventricle heart disease, a research team has revealed the role of leakage from the liver's lymphatic system, and used a novel procedure to seal off those leaks and improve symptoms in patients.

29 Jun 2017

New therapeutic approach offers hope for individuals with debilitating bone cancer

An Australian-led research team has demonstrated a new therapeutic approach that can re-build and strengthen bone, offering hope for individuals with the debilitating bone cancer, multiple myeloma.

29 Jun 2017

Study sheds light on how key protein allows hearing to work

Although the basic outlines of human hearing have been known for years – sensory cells in the inner ear turn sound waves into the electrical signals that the brain understands as sound – the molecular details have remained elusive.

29 Jun 2017

New lab-on-a chip predicts preterm birth risk

Preterm birth is the leading cause of neonatal morbidity and mortality. Among the many underlying causes of pregnancy-associated complications, it is known that infection and inflammation are highly significant risk factors.

29 Jun 2017

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Many potent anti-cancer drugs have major drawbacks -- they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells.

29 Jun 2017

Scientists discover, count and determine new mitochondrial proteome in baker's yeast

Mitochondria, best known for their role as powerhouses of eukaryotic cells, fulfill numerous vital functions. Knowledge about the precise protein composition as well as the functions of individual proteins is essential to understand fundamental processes of cell biology and diseases that are caused by cellular defects.

29 Jun 2017

Adding new antibody to chemotherapy could bolster effects of cancer treatment

Adding an investigational antibody to the chemotherapy rituximab appears to restore its cancer-killing properties in certain leukemia patients with a natural resistance to the drug, according to a small, proof-of-concept study by Duke Cancer Institute researchers.

29 Jun 2017

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G Protein News and Research

Researchers discover differences between mice and humans in function of insulin-producing beta cells

New portable device can quickly find markers of sepsis from single drop of blood

Finnish mothers carry rare gene variants that protect them from pre-eclampsia, study finds

NEI-funded research aims to prevent or reverse progression of cataracts

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

Study highlights rate of misdiagnosis in Alzheimer's disease patients with psychosis

Scientists find new clues to how RSV causes disease

Study indicates new element involved in genome instability

Timing of mutations can have effect on health and disease

Differential RNA splicing may play role in prostate cancer disparities in African-American men

Dysfunctional microglia cells contribute to loss of synapses in Alzheimer's disease

New, improved microcontact printing technology offers big hope for disease detection

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

Novel procedure to seal off lymphatic fluid leaks improves symptoms in patients with single-ventricle disease

New therapeutic approach offers hope for individuals with debilitating bone cancer

Study sheds light on how key protein allows hearing to work

New lab-on-a chip predicts preterm birth risk

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Scientists discover, count and determine new mitochondrial proteome in baker's yeast

Adding new antibody to chemotherapy could bolster effects of cancer treatment

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