Mastectomy News and Research

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Mastectomy is surgery to remove the breast (or as much of the breast tissue as possible).

First patient enrolled in phase III study of Bevacizumab and Trastuzumab in early breast cancer

A new international study for women with HER2-positive breast cancer is open for enrollment. The pivotal BETH (BEvacizumab and Trastuzumab Adjuvant Therapy in HER2-positive Breast Cancer) study is a Phase III clinical research trial that is investigating the benefits of combining two monoclonal antibodies, the anti-angiogenic, bevacizumab (Avastin) and the targeted therapy trastuzumab (Herceptin), together with chemotherapy for the treatment of patients with early stage HER2-positive breast cancer.

27 May 2008

Reconstruction innovations for breast cancer patients

Lumpectomy or breast conservation surgery is the most common type of breast cancer surgery currently performed. A benefit of the surgery is that only part of the breast is removed, but a drawback can be the resulting physical appearance of the breast, which may be disfigured, dented or uneven.

23 Apr 2008

Screening mammography in elderly patients beneficial

Although guidelines keep changing regarding screening mammography in elderly patients, those older than 70 years old continue to benefit from this exam, showing that with frequent mammograms breast cancers can be found sooner, according to a recent study conducted by researchers at Jacobi Medical Center and Albert Einstein College of Medicine, in Bronx, NY.

11 Apr 2008

Disparities in postmastectomy breast reconstruction

In a new study examining disparities in postmastectomy breast reconstruction, researchers at Brigham and Women's Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) in Boston, Mass., concluded that lack of patient-provider discussion may contribute to socioeconomic, age and race-related inconsistencies in the use of breast reconstruction after mastectomy.

3 Apr 2008

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for Cancer Research.

2 Apr 2008

MRI's high false positive rate has little impact on women's choice of preventive mastectomy

Magnetic resonance imaging (MRI) falsely detects breast cancer in five out of every six positive scans according to new research into the use of MRI for women with a high, inherited risk of developing the disease.

26 Mar 2008

Cytori Therapeutics receives positive news on breast reconstruction study

Cytori Therapeutics was informed that positive longer-term follow-up data were presented from an independent, investigator-sponsored breast reconstruction study in Japan.

26 Feb 2008

Benefit of removal of the ovaries differs between women with BRCA1 and BRCA2 mutations

The surgical removal of the ovaries has been widely adopted as a cancer-risk-reducing strategy for women with either BRCA1 or BRCA2 mutations.

12 Feb 2008

Infections at incision site more common than expected following breast procedures

Infections at the incision site occurred in more than 5 percent of patients following breast surgery and cost them more than $4,000 each in hospital-related expenses, according to a report in the January issue of Archives of Surgery, one of the JAMA/Archives journals.

22 Jan 2008

American women prefer overly aggressive treatments for breast cancer

Despite a 1990 consensus recommendation from the National Institutes of Health (NIH) that lumpectomy plus radiation was the treatment of choice for early stage breast cancer, the United States continues to have the highest rate of mastectomy surgery among industrialized countries.

9 Jan 2008

Reconstruction surgery rarely discussed with breast cancer patients

A new study finds that most general surgeons do not discuss reconstruction with patients before surgical breast cancer treatment.

28 Dec 2007

Cone-beam breast CT compared to conventional mammography

Cone-beam breast CT provides exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose to conventional 2D mammography, according to a new study by a team of researchers from the University of Texas M. D. Anderson Cancer Center in Houston.

28 Dec 2007

Early results show promise in reducing side effects from anastrozole

A common osteoporosis drug can shield women against the loss of bone mineral density - a side effect of the drug anastrozole which is taken to prevent breast cancer in the IBIS-2 study - according to new data presented at the San Antonio Breast Cancer Symposium.

14 Dec 2007

Breast MRI spots other cancers, may alter treatment plan

In about 20 percent of women with breast cancer who plan to undergo a lumpectomy, breast magnetic resonance imaging reveals important diagnostic information that alters their treatment plan, University of Florida surgeons reported today (Dec. 5).

5 Dec 2007

MIT radar technology fights breast cancer

Treating breast cancer with a type of heat therapy derived from MIT radar research can significantly increase the effectiveness of chemotherapy, according to results from the fourth clinical trial of the technique reported online Nov. 25 in the journal Cancer Therapy.

27 Nov 2007

More women opting to have both breasts removed when cancer has been found in only one breast

Researchers are reporting a 150 percent increase between 1998 and 2003 in American women opting to have both breasts removed when cancer has been found in only one breast—a procedure called contralateral prophylactic mastectomy (CPM).

16 Nov 2007

Cell response to stress signals predicts tumors in women with common pre-breast cancer

A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS.

13 Nov 2007

Cancer conflict with adjuvant chemotherapy

Women under the age of forty with breast cancer who are given drugs in addition to lumpectomies or radiotherapy, known as adjuvant chemotherapy, may not be benefiting from these drugs.

10 Oct 2007

African-American women less likely to have adjuvant cancer therapy than white women

A new study finds that white women more frequently take more of the life-prolonging supplemental therapies used to treat breast cancer than African-American women.

9 Oct 2007

Treatment for breast cancer differs between African-American women and white women

The study found that, among patients with breast cancer that had spread to the lymph nodes, African-Americans were less likely to have adjuvant cancer therapy than white women. In this clinical group, white women were almost five times more likely to take Tamoxifen, a widely-used cancer therapy medication, and over three times more likely to have chemotherapy.