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UGA researcher works to advance effective treatment for infectious mononucleosis

The University of Georgia's Mark Ebell wasn't impressed with research on infectious mononucleosis when he wrote his first published review on it back in the 1990s. He still isn't—a subject he discusses in the April issue of the Journal of the American Medical Association.

3 May 2016

First-ever vaccine to combat Leishmaniasis under development

As scientists scramble to get a Zika virus vaccine into human trials by the end of the summer, a team of researchers is working on the first-ever vaccine to prevent another insect-borne disease - Leishmaniasis - from gaining a similar foothold in the Americas.

27 Apr 2016

SI-2 molecule can inhibit tumor growth in breast cancer mouse model

Cancer cells communicate with their environment through cell molecules that pass on signals to the inside of the cell. The signals help cancer cells multiply and migrate, spreading the disease.

21 Apr 2016

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Researchers at the University of Wisconsin-Madison School of Veterinary Medicine have developed one of the first mouse models for the study of Zika virus. The model will allow researchers to better understand how the virus causes disease and aid in the development of antiviral compounds and vaccines.

20 Apr 2016

Scientists find new way to defend against deadly malarial parasite

The most dangerous malaria parasite, Plasmodium falciparum, is responsible for nearly half a million deaths annually across Africa and Southeast Asia. Of increasing concern, this parasite is now developing resistance to common antimalarial drugs.

15 Apr 2016

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Sepsis represents a serious complication of infection and is one of the leading causes of death and critical illness worldwide due in part to the lack of effective therapies. A report in the American Journal of Pathology provides evidence from both mouse and human studies that SHARPIN, a protein involved in regulating inflammation, has anti-septic effects. These findings may spur development of novel sepsis treatments.

11 Apr 2016

Immune cell with 'Superman' power could lead to novel therapies for type 1 diabetes

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a previously unknown type of immune cell. The discovery opens new avenues in the effort to develop novel therapies for autoimmune diseases such as type 1 diabetes.

6 Apr 2016

Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

For an innovative treatment, which allows to selectively direct nanoparticles of iron oxide into cell targets in the blood to fight chronic inflammatory disorders or cancer that was successfully tested in a cell culture and animal models, Dr. Andrea de Vizcaya Ruiz, was awarded with the Innovation Award in Bionanotechnology Cinvestav-Neolpharma 2015.

6 Apr 2016

Pediatric surgeons who perform very few procedures after graduation may have hard time in the long run

Some pediatric surgeons perform so few rare and complex procedures once they finish their surgical training that they may have a hard time maintaining operative skills in the long run, according to a new study led by researchers at Ann & Robert H. Lurie Children’s Hospital of Chicago.

31 Mar 2016

Research describes first new mouse model for Zika infection in decades

Efforts to combat the rapid spread of Zika virus got a boost this week as researchers at the University of Texas Medical Branch, Galveston (UTMB) announced the first peer-reviewed publication of a mouse model for Zika infection reported in decades.

30 Mar 2016

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

Wellcome Trust Sanger Institute scientists show how the parasite responsible for the neglected tropical disease Black Fever (visceral leishmaniasis) can become resistant to drug treatment. Studying the whole genomes of more than 200 samples of Leishmania donovani revealed that the addition of just two bases of DNA to a gene known as LdAQP1 stops the parasite from absorbing antimonial drugs.

23 Mar 2016

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Understanding the origins of emerging diseases - as well as more established disease agents -- is critical to gauge future human infection risks and find new treatment and prevention approaches. This holds true for malaria, which kills more than 500,000 people a year. Symptoms, including severe anemia, pregnancy-associated malaria, and cerebral malaria, have been linked to the parasite's ability to cause infected red blood cells to bind to the inner lining of blood vessels.

22 Mar 2016

New method to harvest stem cells reduces side effects for donors

Australian scientists have developed a new method for harvesting stem cells, which is less invasive and reduces side effects for donors.

16 Mar 2016

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

microRNAs (miRs) are small endogenous noncoding RNA molecules (20–23 nucleotides) derived from imperfectly paired hairpin RNA structures naturally encoded in the genome that act specifically as triggering molecules to control translational repression or mRNA degradation.

11 Mar 2016

Advances in the field of MPI: an interview with Professor Kannan Krishnan

In around 2004, there was a Phillips paper that discussed a new imaging technique called MPI. At that time, I had an eager, promising graduate student named Matt Ferguson who wanted a project, so I asked him to take a look.

From Bruker BioSpin Group 1 Mar 2016

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Rigel Pharmaceuticals Inc. today announced that it has initiated a Phase 2 clinical trial to evaluate fostamatinib, its oral SYK inhibitor, as a potential treatment for autoimmune hemolytic anemia (AIHA).

25 Feb 2016

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

Cancer immunology is based upon boosting the body's own immune system to vanquish malignancies. It is among the fastest growing areas of oncology research. Researchers at UC San Diego Moores Cancer Center have launched three clinical trials to test the safety and efficacy of a novel cellular-immunotherapy that uses modified T cells - one of the immune system's primary weapons - to treat three different types of blood cancer that often defy existing therapies.

24 Feb 2016

Spleen News and Research

UGA researcher works to advance effective treatment for infectious mononucleosis

First-ever vaccine to combat Leishmaniasis under development

SI-2 molecule can inhibit tumor growth in breast cancer mouse model

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Scientists find new way to defend against deadly malarial parasite

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Immune cell with 'Superman' power could lead to novel therapies for type 1 diabetes

Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

Pediatric surgeons who perform very few procedures after graduation may have hard time in the long run

Research describes first new mouse model for Zika infection in decades

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

New method to harvest stem cells reduces side effects for donors

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

Advances in the field of MPI: an interview with Professor Kannan Krishnan

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

New method could help scientists better predict disease-causing mutations in people's genes

Mtss1 'tumour suppressor' for CML

CTI BioPharma announces Q4 and FY 2015 earnings

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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