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New deep learning algorithm predicts effects of rare genetic variants

Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome.

25 Sep 2024

Deadly high blood pressure during pregnancy is on the rise

Sara McGinnis was pregnant with her second child and something felt off. Her body was swollen. She was tired and dizzy.

25 Sep 2024

Increasing daily consumption of flavonoid-rich foods may lower dementia risk

Research shows that flavonoid-rich diets, including tea and red wine, are associated with a lower risk of dementia in genetically susceptible individuals.

25 Sep 2024

A faster, cheaper method to detect immune autoantibodies in whole blood

Researchers developed a quick and affordable whole-blood assay to detect autoantibodies against type I IFNs, enabling rapid diagnostics for immune disorders. This new method has potential clinical impact by addressing key limitations of current tests.

25 Sep 2024

Women remain underserved in cardiovascular disease treatment despite advances

Women in the UK, and elsewhere, are still missing out on vital treatment for their No 1 killer - cardiovascular disease - despite significant progress in the medical management of heart disease and stroke, concludes a consensus statement published online in the journal Heart.

24 Sep 2024

Study links youth prediabetes to increased pregnancy risks later in life

New research conducted at Columbia Mailman School of Public Health and Mount Sinai School of Medicine shows a link between prediabetes among young people and adverse pregnancy outcomes later in life.

24 Sep 2024

New FDA award fuels research into autosomal dominant tubulointerstitial kidney disease

Critical Path Institute (C-Path) is thrilled to announce its Polycystic Kidney Disease Outcomes Consortium (PKDOC) has been awarded an Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) focused Broad Agency Announcement (BAA) contract from the U.S. Food and Drug Administration (FDA).

24 Sep 2024

New approach to B-ALL treatment reduces side effects and enhances survival

Clinical trial results from St. Jude Children's Research Hospital demonstrate benefits to using genomics and early treatment response to guide risk classification of children with B-cell acute lymphoblastic leukemia (B-ALL).

24 Sep 2024

Music therapy improves sleep and comfort in preterm infants

Daily music interventions significantly improved comfort and sleep transitions in preterm infants without affecting physiological stability. This study highlights the potential of non-pharmacological music therapy in neonatal care.

24 Sep 2024

Targeted obesity programs reduce lipid-related heart disease risk in children

Researchers assess the lipid profiles of obese children and adolescents and their health implications.

24 Sep 2024

New guidelines for cardiovascular management in noncardiac surgery released

The 2024 guideline for cardiovascular management of adults undergoing noncardiac surgery reflects a decade of updates and new evidence since the guideline's last release in 2014.

24 Sep 2024

Innovative ALS study receives $22 million grant for experimental drug

Mayo Clinic in Florida has received a grant from the National Institute of Neurological Disorders and Stroke (NIDS) to begin an innovative study that will provide hundreds of patients with amyotrophic lateral sclerosis (ALS) access to the experimental drug ibudilast over six months.

24 Sep 2024

Incidence and risk factors of an invasive fungal lung infection among COVID-19 patients

Study reveals 0.4%-2.7% incidence of COVID-19-associated pulmonary aspergillosis in severe patients, highlighting significant mortality risks and risk factors.

24 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

New roadmap to advance UK’s bioelectronics for healthcare through materials innovation

The Henry Royce Institute has published the Materials for Bioelectronics in Healthcare Strategy and Action Plan a comprehensive report that aims to help future-proof the UK’s bioelectronics for healthcare sector through materials innovation.

24 Sep 2024

New AI approach enhances cardiovascular risk assessment

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial.

24 Sep 2024

New drug combo shows promise for deeper remission in chronic leukemia

Researchers leading the SWOG S1712 clinical trial have found that adding ruxolitinib to standard tyrosine kinase inhibitor (TKI) treatment for patients with chronic-phase chronic myeloid leukemia (CP-CML) significantly increased the percentage of patients who had a molecular response deep enough to warrant discontinuing treatment.

24 Sep 2024

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Study explores the potential to repurpose neuroactive drugs, originally approved for neurological disorders, for the treatment of glioblastoma. Vortioxetine, an antidepressant, showed promising anti-glioblastoma activity, significantly reducing tumor size in preclinical trials.

24 Sep 2024

Medicare coverage for obesity drug raises questions

Millions of older Americans with obesity could potentially get Medicare's help with the hefty price of a weight-loss medication in order to reduce their high risk of heart problems.

23 Sep 2024

Human challenge study reveals lasting cognitive decline after mild COVID-19

Researchers from the UK conducted the first human challenge study of SARS-CoV-2, revealing long-lasting cognitive deficits in unvaccinated participants infected with the virus, especially in memory and executive function.

23 Sep 2024