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Results of ibrutinib Phase 2 study in patients with mantle cell lymphoma published in NEJM

Pharmacyclics, Inc. today announced that The New England Journal of Medicine published results of a Phase 2 study evaluating the investigational oral Bruton's tyrosine kinase inhibitor ibrutinib in patients with relapsed/refractory mantle cell lymphoma online.

20 Jun 2013

Researchers develop method to identify aggressive prostate cancers

Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms. The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment.

20 Jun 2013

LDL cholesterol blood levels: an interview with Dr. Harvey Kaufman

What is LDL cholesterol? What blood level of LDL cholesterol is considered optimal and why are high levels of LDL cholesterol a key marker of death risk from heart disease? Dr. Harvey Kaufman, senior medical director of Quest Diagnostics gives us some answers.

From Quest Diagnostics 19 Jun 2013

Study describes molecular bases of resistance to new chemotherapeutic agent in familial breast and ovarian cancers

It is estimated that between 5% and 10% of breast and ovarian cancers are familial in origin, which is to say that these tumours are attributable to inherited mutations from the parents in genes such as BRCA1 or BRCA2.

19 Jun 2013

Insulin degludec has reduced risk of recurrent hypoglycemia than insulin glargine

Insulin degludec (Tresiba), a new ultra-long-acting insulin, has a similar or reduced risk of recurrent hypoglycemia—low blood sugar—compared with the commercially available insulin glargine, a new meta-analysis study finds.

19 Jun 2013

Thrombolytic treatment after stroke associated with reduced in-hospital mortality

In a study that included nearly 60,000 patients with acute ischemic stroke, thrombolytic treatment (to help dissolve a blood clot) that was started more rapidly after symptom onset was associated with reduced in-hospital mortality and intracranial hemorrhage and higher rates of independent walking ability at discharge and discharge to home, according to a study in the June 19 issue of JAMA.

19 Jun 2013

Scientists discover new drug that cripples TB bug by dissolving its protective fatty coating

Most humans would like to shed their fatty exteriors, but tuberculosis (TB)-causing bacteria rely on theirs for survival. Scientists at the University of Medicine and Dentistry of New Jersey (UMDNJ)-New Jersey Medical School have now discovered a drug that cripples the TB bug by dissolving its protective fatty coating, a finding that could eventually be used to improve TB treatment in humans. The study has been posted online by Nature Chemical Biology.

19 Jun 2013

Stress exposure may be associated with increased risk of aggressive breast cancer

Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of breast cancer, researchers from the University of Chicago report in the July 2013 issue of the journal Cancer Prevention Research.

19 Jun 2013

NO2 exposure in infancy is strongly linked with later development of childhood asthma

A research team led by UCSF scientists has found that exposure in infancy to nitrogen dioxide (NO2), a component of motor vehicle air pollution, is strongly linked with later development of childhood asthma among African Americans and Latinos.

19 Jun 2013

Scientists discover new mechanism to protect body from harmful bacteria

Scientists at the University of Calgary's Faculty of Medicine have discovered a mechanism that is used to protect the body from harmful bacteria. Platelets, a component of blood typically associated with clotting, were discovered to actively search for specific bacteria, and upon detection, seal it off from the rest of the body. The findings, which were published in Nature Immunology this week, provide the science community with a greater understanding of immunity.

19 Jun 2013

Storytelling may improve medical students' perceptions of people affected by dementia

Treating patients with dementia can be viewed as a difficult task for doctors, but Penn State College of Medicine researchers say that storytelling may be one way to improve medical students' perceptions of people affected by the condition. Participation in a creative storytelling program called TimeSlips creates a substantial improvement in student attitudes.

19 Jun 2013

Home environment and parenting can influence child's health by shaping dietary and physical behaviors

Kids whose moms encourage them to exercise and eat well, and model those healthy behaviors themselves, are more likely to be active and healthy eaters, according to researchers at Duke Medicine.

19 Jun 2013

Diet, lifestyle and environment attribute to the cause of majority of cancer cases

Diet, lifestyle and the environment are all factors attributed to the cause of the majority of cancer cases and it has been estimated that up to half of all cancers may be preventable according to research by a University of Leicester scientist.

19 Jun 2013

Ico Therapeutics completes Phase 2 iDEAL study for treatment of diabetic macular edema

iCo Therapeutics Inc. announced today that it has completed enrollment of its Phase 2 iDEAL study evaluating the efficacy and safety after repeated injections of iCo-007 in patients with Diabetic Macular Edema (DME). The study has shown a good safety profile with no drug-related serious adverse events to date.

19 Jun 2013

World-renowned leader in care and treatment of burn injury awarded highest honor from Loyola University

Richard L. Gamelli, MD, FACS, a world-renowned leader in the care and treatment of burn injury, is being awarded Loyola University Chicago Stritch School of Medicine's highest honor.

19 Jun 2013

New framework to improve safety and effectiveness of surgical procedures, implantable devices

An international team of investigators co-led by Weill Cornell Medical College is offering a new framework for evidence-based surgery and device research, similar to the kind of risk and benefit analysis used in evidence-based medicine.

19 Jun 2013

Montana scientist receives ICAAC Young Investigator Award for research on memory responses to infection

Joshua Obar, Ph.D., Department of Immunology and Infectious Diseases, Montana State University-Bozeman, has been honored with a 2013 ICAAC Young Investigator Award for his research on factors affecting the regulation of immunological memory responses to infection.

19 Jun 2013

Taxing less-healthy foods motivates people to make healthier choices, says study

Labeling foods and beverages as less-healthy and taxing them motivates people to make healthier choices, finds a recent study in the American Journal of Preventive Medicine.

19 Jun 2013

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

An analysis by the Evidence-based Practice Center at Oregon Health & Science University has found that previously published clinical trial studies about a controversial bone growth product used in spinal surgeries overstated the product's effectiveness.

19 Jun 2013

New breakthrough in chemical nanoengineering may help develop light-regulated therapeutic molecules

The scientific cooperation between chemists, biotechnologists and physicists from various Catalan institutes, headed by Pau Gorostiza, from the Institute for Bioengineering of Catalonia (IBEC), and Ernest Giralt, from the Institute for Research in Biomedicine (IRB Barcelona), has led to a breakthrough that will favor the development of light-regulated therapeutic molecules.

19 Jun 2013

Medicine News and Research

Results of ibrutinib Phase 2 study in patients with mantle cell lymphoma published in NEJM

Researchers develop method to identify aggressive prostate cancers

LDL cholesterol blood levels: an interview with Dr. Harvey Kaufman

Study describes molecular bases of resistance to new chemotherapeutic agent in familial breast and ovarian cancers

Insulin degludec has reduced risk of recurrent hypoglycemia than insulin glargine

Thrombolytic treatment after stroke associated with reduced in-hospital mortality

Scientists discover new drug that cripples TB bug by dissolving its protective fatty coating

Stress exposure may be associated with increased risk of aggressive breast cancer

NO2 exposure in infancy is strongly linked with later development of childhood asthma

Scientists discover new mechanism to protect body from harmful bacteria

Storytelling may improve medical students' perceptions of people affected by dementia

Home environment and parenting can influence child's health by shaping dietary and physical behaviors

Diet, lifestyle and environment attribute to the cause of majority of cancer cases

Ico Therapeutics completes Phase 2 iDEAL study for treatment of diabetic macular edema

World-renowned leader in care and treatment of burn injury awarded highest honor from Loyola University

New framework to improve safety and effectiveness of surgical procedures, implantable devices

Montana scientist receives ICAAC Young Investigator Award for research on memory responses to infection

Taxing less-healthy foods motivates people to make healthier choices, says study

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

New breakthrough in chemical nanoengineering may help develop light-regulated therapeutic molecules

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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