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In vitro HDRA improves survival, prognosis of patients with NSCLC: Study

Chemotherapy is the best broad defense against cancer recurrence after surgical resection. However, it is difficult to predict which patients will benefit from which regimen of anticancer drugs, if at all. Building on existing knowledge, a study published in the September edition of the Journal of Thoracic Oncology, analyzed the usefulness of adjuvant chemotherapy for non-small cell lung cancer based on the histoculture drug response assay.

2 Sep 2010

Evotec AG announces Closing conditions to acquire DeveloGen

Evotec AG today announced the Closing of the agreement to acquire DeveloGen as announced in detail on 14 July 2010.

2 Sep 2010

CDC launches new online video to provide information on Assisted Reproductive Technology

Reproductive health experts at the Centers for Disease Control and Prevention (CDC) have launched three new online videos to provide science-based information for anyone considering Assisted Reproductive Technology (ART).

2 Sep 2010

Second-hand smoke triggers complex inflammatory response

Second-hand smoke is associated with a number of diseases and conditions, including cancer, heart disease, and emphysema. It is an irritant to lung tissue and blood vessels, but the processes through which the body reacts to second-hand smoke comprise a mystery scientists are only beginning to unravel. Researchers at the University of Colorado-Denver are currently studying how second-hand smoke affects the lungs of rats, and so far it appears that second-hand smoke triggers a complex inflammatory response.

27 Aug 2010

Luminex launches FDA-cleared xTAG Cystic Fibrosis 60 Kit v2 diagnostic test

Luminex Corporation, the worldwide leader in multiplexed solutions, today announced the full commercial launch of its xTAG Cystic Fibrosis 60 Kit v2, a new diagnostic test that can simultaneously screen a single blood sample for up to 60 cystic fibrosis-causing genetic mutations in a matter of hours.

From Thermo Fisher Scientific Inc. 27 Aug 2010

Researchers identify molecule to slow down dysfunctional immune response in hemorrhagic shock

Researchers have isolated a molecule, small enough to be used as a drug, that can shut down a dysfunctional immune response that causes deadly hemorrhagic shock, results in delayed death of heart attack patients, promotes rejection of transplanted organs and destroys joints in patients with rheumatoid arthritis, according to a paper published in Molecular Immunology.

27 Aug 2010

Biomoda's CyPath assay for lung cancer detection receives Canadian patent

Cancer diagnostics company Biomoda, Inc. has received a notice of allowance for a Canadian patent application for a method of using its proprietary porphyrin-based compound that binds to cancer cells and causes them to fluoresce under specific frequencies of light when viewed under a fluorescent microscope.

26 Aug 2010

The AFA, Fertility SOURCE partner to provide information on donor egg cycles for patients

Infertility is an unexpected obstacle for many people, and the journey can be unpredictable. Patients may find themselves at a crossroads after multiple failed attempts with fertility treatments, and begin to look for other options.

25 Aug 2010

Human umbilical cord blood cells appear to protect astrocytes from cell death: Research

Human umbilical cord blood cells (HUCB) used to treat cultured rat brain cells (astrocytes) deprived of oxygen appear to protect astrocytes from cell death after stroke-like damage, reports a team of researchers from the University of South Florida (USF) Department of Neurosurgery and Brain Repair.

25 Aug 2010

Warner Chilcott receives FDA response to citizen petition for ASACOL and ASACOL HD products

Warner Chilcott plc today announced that it has received the Food and Drug Administration's response to a citizen petition it had filed regarding its ASACOL and ASACOL HD products.

25 Aug 2010

Judge blocks federal funding of human embryonic stem cell research

The Washington Post: "A federal judge on Monday blocked the Obama administration from funding human embryonic stem cell research, ruling that the support violates a federal law barring the use of taxpayer money for experiments that destroy human embryos.

25 Aug 2010

Alnylam Pharmaceuticals to present results on RNAi therapeutics at ACS National Meeting

Alnylam Pharmaceuticals, Inc.,a leading RNAi therapeutics company, announced today that it will make a total of 16 oral presentations at the American Chemical Society (ACS) Fall 2010 240th National Meeting & Exposition being held in Boston, Mass. from August 22-26, 2010.

24 Aug 2010

Pharmasset commences dosing in PSI-7977 Phase 2b study for chronic hepatitis C

Pharmasset, Inc. announced today that dosing has begun in a Phase 2b study of PSI-7977, a nucleotide analog polymerase inhibitor for the treatment of chronic hepatitis C (HCV). The trial will evaluate PSI-7977 200mg QD and 400mg QD in combination with pegylated interferon alfa 2a and ribavirin, the current standard of care (SOC) in patients with HCV genotype 1 who have not been treated previously.

24 Aug 2010

IVD Technology to launch first annual Virtual Conference and Tradeshow

IVD Technology, the only trade media brand designed exclusively for manufacturers of in vitro diagnostic products, today announced the launch of its first annual Virtual Conference and Tradeshow to be held on September 28, 2010.

24 Aug 2010

Arrayit selects PMA pathway for OvaDx Pre-Symptomatic Ovarian Cancer Screening Test

Arrayit Corporation, a leader in life sciences and healthcare technology, announces today that the company has chosen the Premarket Approval pathway for its OvaDx Pre-Symptomatic Ovarian Cancer Screening Test. While the standard for a PMA is higher than for a 510(k), the company believes that a PMA OvaDx submission can achieve a Class III PMA approval, the most stringent approval level granted by the FDA for in vitro diagnostic devices.

23 Aug 2010

Cyprotex launches new in vitro toxicology service

Cyprotex PLC, the preclinical ADME Tox services company, today announces the launch of its new in vitro toxicology service, branded as Cyprotox(R). Supporting the new service is an additional 90 square metres of laboratory space at Cyprotex's Macclesfield, UK facility housing the latest technology in multi-parametric automated fluorescent imaging and cellular analysis. This gives Cyprotex's Macclesfield site the same in vitro toxicology capabilities as those of Apredica (Watertown, MA, USA), which Cyprotex acquired on 6 August 2010.

From Thermo Fisher Scientific Inc. 20 Aug 2010

Bacterial pathogens require vitamin B6 biosynthesis enzymes for virulence: Study

Scientists have determined that Helicobacter pylori, the bacterium that causes peptic ulcers and some forms of stomach cancer, requires the vitamin B6 to establish and maintain chronic infection, according to research published this week in the online journal mBio-. This finding, along with the identification of the enzyme the microbe requires to utilize the vitamin, could lead to the development of an entirely new class of antibiotics.

20 Aug 2010

Cetero Research expands Clinical Dermatology and Transdermal Delivery System services

Cetero Research, the leading early stage contract research organization (CRO), today announced the expansion of multiple Clinical Dermatology and Transdermal Delivery System (TDDS) services to four Cetero clinical facilities.

20 Aug 2010

Cognition Therapeutics receives grant to develop small-molecule drug candidate for Alzheimer's disease

The Alzheimer's Drug Discovery Foundation (ADDF) announced today that it has awarded a grant of $228,668 to Cognition Therapeutics (CogRx) to develop small molecule drugs that block the action of the toxic "oligomers" thought responsible for Alzheimer's disease (AD).

19 Aug 2010

IRIS International announces approval of share repurchase program

IRIS International, Inc., a leading manufacturer of automated in-vitro diagnostics systems and consumables for use in hospitals and commercial laboratories worldwide, today announced that, effective immediately, its Board of Directors has approved a repurchase program for up to $10 million in shares of the Company's common stock over a twelve month period.

18 Aug 2010

in vitro News and Research

In vitro HDRA improves survival, prognosis of patients with NSCLC: Study

Evotec AG announces Closing conditions to acquire DeveloGen

CDC launches new online video to provide information on Assisted Reproductive Technology

Second-hand smoke triggers complex inflammatory response

Luminex launches FDA-cleared xTAG Cystic Fibrosis 60 Kit v2 diagnostic test

Researchers identify molecule to slow down dysfunctional immune response in hemorrhagic shock

Biomoda's CyPath assay for lung cancer detection receives Canadian patent

The AFA, Fertility SOURCE partner to provide information on donor egg cycles for patients

Human umbilical cord blood cells appear to protect astrocytes from cell death: Research

Warner Chilcott receives FDA response to citizen petition for ASACOL and ASACOL HD products

Judge blocks federal funding of human embryonic stem cell research

Alnylam Pharmaceuticals to present results on RNAi therapeutics at ACS National Meeting

Pharmasset commences dosing in PSI-7977 Phase 2b study for chronic hepatitis C

IVD Technology to launch first annual Virtual Conference and Tradeshow

Arrayit selects PMA pathway for OvaDx Pre-Symptomatic Ovarian Cancer Screening Test

Cyprotex launches new in vitro toxicology service

Bacterial pathogens require vitamin B6 biosynthesis enzymes for virulence: Study

Cetero Research expands Clinical Dermatology and Transdermal Delivery System services

Cognition Therapeutics receives grant to develop small-molecule drug candidate for Alzheimer's disease

IRIS International announces approval of share repurchase program

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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