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Researchers develop new gene therapy to thwart potential influenza pandemic

Researchers at the Perelman School of Medicine, University of Pennsylvania have developed a new gene therapy to thwart a potential influenza pandemic. Specifically, investigators in the Gene Therapy Program, Department of Pathology and Laboratory Medicine, directed by James M. Wilson, MD, PhD, demonstrated that a single dose of an adeno-associated virus expressing a broadly neutralizing flu antibody into the nasal passages of mice and ferrets gives them complete protection and substantial reductions in flu replication when exposed to lethal strains of H5N1 and H1N1 flu virus.

30 May 2013

Research explores connections between the brain, immune system and psychological functions

It's true that the brain governs the body, but the body also governs the brain, for example when the immune defense system makes us rest when we're sick. This is shown in research that the world's leading researchers and Nobel laureates will be presenting at an international conference in the research field of psychoneuroimmunology in Stockholm in June.

30 May 2013

Standard strategies to prevent lethal blood clots more effective than temporary placement of filters

The temporary placement of umbrella-like, metal mesh filters in abdominal veins to stop potentially lethal blood clots from traveling to the lungs during and after weight loss surgery may actually increase the risk of death in morbidly obese patients, according to new Johns Hopkins research.

30 May 2013

Researchers analyze risk factors for fat necrosis in women undergoing breast reconstruction

For women undergoing breast reconstruction after mastectomy, the weight of the tissue flap used affects the risk of an important complication called fat necrosis, reports a study in Plastic and Reconstructive Surgery—Global Open, the official open-access medical journal of the American Society of Plastic Surgeons.

30 May 2013

Endovascular stroke therapy should be limited to use within clinical trials, say physicians

Devices snaked into the brain artery of a patient experiencing a stroke that either snatch and remove the offending clot or pump a dissolving drug into the blockage should primarily be used within a clinical trial setting, say a team of vascular neurologists at Mayo Clinic in Florida.

30 May 2013

Viewpoints: Medical professionals and near misses; Two tea partiers diverge on Medicaid expansion; Obamacare's 'death by a thousand cuts'

A near miss, like any error, is an opportunity to examine how mistakes are made and what changes might prevent them. Yet we have no idea how many near misses there are. Many experts feel that near-miss errors dwarf the number of known errors, a number that is already too high for comfort. (According to a 2006 report, medication errors alone injure an estimated 1.5 million patients a year.) But the instinct for most medical professionals is to keep these shameful mistakes to ourselves (Danielle Ofri, 5/28).

30 May 2013

Disabled Medicare patients with CRN more likely to have at least one ER visit, study finds

Disabled Medicare patients under the age of 65 who don't take their prescription medications because of cost concerns are more likely to have at least one emergency department visit during a one-year period.

30 May 2013

Researchers examine quality of information given by sales reps when promoting drugs to physicians

Dr. Genevi-ve Durrieu (from the Pharmaco-epidemiology team assessing the use of medication and the risks involved, Unit 1027 "Epidemiology and public health analyses: risks, chronic diseases and handicaps" - Inserm / Universit- Toulouse III - Paul Sabatier) led the French part of this study, the results of which are published in the Journal of General Internal Medicine. Within the framework of this international study, is France proving to be a model student?

30 May 2013

Study details Medicare spending variations

The analysis finds health differences explain as much as 85 percent of cost variations around the country.

30 May 2013

PTSD following heart attack is associated with poor sleep, study finds

Clinicians have long speculated that poor sleep may be a mechanism involved in the higher risk of further cardiac events or death among those with post-traumatic stress disorder following a heart attack, but the association between PTSD and sleep after a heart event has been unknown.

30 May 2013

Landmark study reveals new way to treat strokes

University of Leicester researchers have contributed to a landmark study which has revealed a new way to treat strokes caused by bleeding inside the brain.

30 May 2013

Elective hernia surgery offers value-for-money, improves quality of life for patients

New research suggesting that elective hernia surgery offers value-for-money and improved quality of life for patients has been published by the Journal of the Royal Society of Medicine.

30 May 2013

In rural Alaska, new rules reshape care often hampered by isolation

Two news outlets examine some of the difficulties in providing care in Alaska.

30 May 2013

Scientists find that 'junk DNA' could promote cancer progression

Scientists at The University of Nottingham have found that a genetic rogue element produced by sequences until recently considered 'junk DNA' could promote cancer progression.

30 May 2013

Restoring blood vessels may help cure type 1 diabetes, finds University of Missouri scientist

Millions of people with type 1 diabetes depend on daily insulin injections to survive. They would die without the shots because their immune system attacks the very insulin-producing cells it was designed to protect. Now, a University of Missouri scientist has discovered that this attack causes more damage than scientists realized.

30 May 2013

Researchers codify age-specific probabilities of live birth after IVF with frozen eggs

Researchers from New York Medical College and the University of California Davis have for the first time codified age-specific probabilities of live birth after in vitro fertilization (IVF) with frozen eggs.

30 May 2013

Adult stem cells combined with new drug could hold key to curing type 1 diabetes

29 May 2013

Strengthening miniaturized titanium-based medical devices: an interview with Dr Masaru Rao, University of California, Riverside

While titanium is used widely for more conventional macro-scale medical devices (e.g. hip implants, dental implants, and cardiac pacemakers), its use for micro- and nano-scale devices has been limited thus far.

29 May 2013

Targacept initiates TC-5214 Phase 2b clinical study in patients with OAB

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced the initiation of a Phase 2b clinical study of TC-5214 as a treatment for overactive bladder.

29 May 2013

Atopix awarded grant to pursue development of OC459 for atopic dermatitis

Atopix Therapeutics Ltd, a biopharmaceutical company developing a novel class of anti-allergic medicines, has been awarded a £1.7 million grant from the UK Biomedical Catalyst fund to pursue development of OC459 in the treatment of moderate-to-severe atopic dermatitis (a form of eczema).

29 May 2013

Medicine News and Research

Researchers develop new gene therapy to thwart potential influenza pandemic

Research explores connections between the brain, immune system and psychological functions

Standard strategies to prevent lethal blood clots more effective than temporary placement of filters

Researchers analyze risk factors for fat necrosis in women undergoing breast reconstruction

Endovascular stroke therapy should be limited to use within clinical trials, say physicians

Viewpoints: Medical professionals and near misses; Two tea partiers diverge on Medicaid expansion; Obamacare's 'death by a thousand cuts'

Disabled Medicare patients with CRN more likely to have at least one ER visit, study finds

Researchers examine quality of information given by sales reps when promoting drugs to physicians

Study details Medicare spending variations

PTSD following heart attack is associated with poor sleep, study finds

Landmark study reveals new way to treat strokes

Elective hernia surgery offers value-for-money, improves quality of life for patients

In rural Alaska, new rules reshape care often hampered by isolation

Scientists find that 'junk DNA' could promote cancer progression

Restoring blood vessels may help cure type 1 diabetes, finds University of Missouri scientist

Researchers codify age-specific probabilities of live birth after IVF with frozen eggs

Adult stem cells combined with new drug could hold key to curing type 1 diabetes

Strengthening miniaturized titanium-based medical devices: an interview with Dr Masaru Rao, University of California, Riverside

Targacept initiates TC-5214 Phase 2b clinical study in patients with OAB

Atopix awarded grant to pursue development of OC459 for atopic dermatitis

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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